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47721“…She was then referred after a year with skin tightening (indurated plaque) over loin and chest. CK was elevated without clinical evidence of muscle weakness and ANA 1:1600 positive with negative ENA and normal DsDNA/Compliments. …”
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47722“…HIV and Hepatitis screens were negative. CT chest, abdomen and pelvis and subsequent PET-CT scan were unremarkable. …”
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47723por Zuccon, William, Comassi, Paolo, Adriani, Luca, Bergamaschini, Giulio, Bertin, Elena, Borromeo, Raffaella, Corti, Serena, De Petri, Federica, Dolci, Francesco, Galmozzi, Attilio, Gigliotti, Alberto, Gualdoni, Livio, Guerra, Claudia, Khosthiova, Anna, Leati, Giovanni, Lupi, Giuseppe, Moscato, Paolo, Perotti, Vittorio, Piantelli, Miriam, Ruini, Alain, Sportelli, Silvia, Susca, Micaela, Troiano, Carmine, Benelli, Giampaolo, Buscarini, Elisabetta, Canetta, Ciro, Merli, Guido, Scartabellati, Alessandro, Melilli, B.S.C., Giovanni, Sfogliarini, Roberto, Pellegatta, Germano, Viganò, Giovanni“…In a simplified classification of the tomographic examination of the chest, mostly 3D and 2C lesions were found in the deceased patients with a prevalence of severe and moderate forms, whilst in the survivors the distribution appears with a prevalence of medium and moderate forms. …”
Publicado 2021
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47724“…Otherwise, her full blood count, electrolytes, renal and liver function tests, chest X-ray, urine dipstick, hepatitis serology, ANCA profile, B12, folate and ferritin were unremarkable. …”
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47725por Urwyler, Pascal, Charitos, Panteleimon, Moser, Stephan, Heijnen, Ingmar A. F. M., Trendelenburg, Marten, Thoma, Reto, Sumer, Johannes, Camacho-Ortiz, Adrián, Bacci, Marcelo R., Huber, Lars C., Stüssi-Helbling, Melina, Albrich, Werner C., Sendi, Parham, Osthoff, Michael“…Inclusion criteria: - Signed informed consent - Age 18-85 years - Evidence of pulmonary involvement on CT scan or X-ray of the chest - Duration of symptoms associated with COVID-19 ≤ 10 days - At least one of the following risk factors for progression to mechanical ventilation on the day of enrolment: 1) Arterial hypertension 2) ≥ 50 years 3) Obesity (BMI ≥ 30 kg/m2) 4) History of cardiovascular disease 5) Chronic pulmonary disease 6) Chronic renal disease 7) C-reactive protein > 35mg/L 8) Oxygen saturation at rest of ≤ 94% when breathing ambient air Exclusion criteria: - Incapacity or inability to provide informed consent - Contraindications to the class of drugs under investigation (C1 esterase inhibitor) - Treatment with tocilizumab or another IL-6R or IL-6 inhibitor before enrolment - History or suspicion of allergy to rabbits - Pregnancy or breast feeding - Active or anticipated treatment with any other complement inhibitor - Liver cirrhosis (any Child-Pugh score) - Admission to an ICU on the day or anticipated within the next 24 hours of enrolment - Invasive or non-invasive ventilation - Participation in another study with any investigational drug within the 30 days prior to enrolment - Enrolment of the study investigators, their family members, employees and other closely related or dependent persons INTERVENTION AND COMPARATOR: Patients randomized to the experimental arm will receive conestat alfa in addition to standard of care (SOC). …”
Publicado 2021
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47726por Mussetti, Alberto, Maluquer, Clara, Tebe Cordomi, Cristian, Condom, Maria, Molina-Mata, Kevin, Marin Jimenez, Juan Antonio, Tapia Tapia, Jose Carlos, Gavira Diaz, Javier, Majem Tarruella, Margarita, Falgas, Felip, Llobera Rius, Laia, Fort Culillas, Roser, Llavata Martí, Lucia, Moreno, Miriam, Vives, Susana, Coll, Rosa, Martin Batista, Silvia, Talarn, Carme, Sagüés, Miguel, Bazarbachi, Ali, Salazar, Ramon, Sureda Balari, Anna“…All the other symptoms (myalgia, diarrhea, anosmia, ageusia, fatigue, headache) had an incidence < 10%. Chest X-ray was abnormal in 60% of cases. Regarding in-hospital treatments, 85% received antibiotics, 76% hydroxychloroquine, 12% tocilizumab, 30% corticoids, 70% prophylactic anticoagulation and 55% oxygen support. …”
Publicado 2020
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47727“…Urine dip was negative for protein/blood/leuc/nitrites. Chest X-ray showed mild bronchial wall thickening in the right lower zone with a few ill-defined small opacites of indeterminate significance. …”
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47728por Chatwani, Bhoomija, Flaherty, Shelby, Liu, Sharon, Theberge, Marc, Zeller, Mark, Anderson, Kristian, Boisen, Matt, Branco, Luis, Garry, Robert, Drouin, Arnaud, Fusco, Dahlene“…Demographic and Clinical Characteristics [Image: see text] The bivariate analysis results showed that the gender (female, P=0.0354), history of stroke or transient ischemic attack (P=0.0382), chest pain from narrow heart vessels (P=0.0479), deep venous thrombosis (P=0.0241) and abnormal kidney function (P=0.0142) were associated with Post-COVID syndrome. …”
Publicado 2021
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47729por Devarashetty, Sindhu, Le Blanc, Kimberly, Grewal, Udhayvir Singh, Walton, Jacqueline, Jones, Tabitha, Shi, Runhua, Master, Samip R, Mansour, Richard Preston, Ramadas, Poornima“…Comorbidities and previous history included acute chest syndrome in 65.96%, avascular necrosis in 36.96%, leg ulcers in 8.7%, hypertension in 8.7%, sickle cell retinopathy in 14.57%, cerebrovascular disease in 26.19%, chronic kidney disease in 7.69%, venous thromboembolism (VTE) in 20.41%, 10.41% were on anticoagulation, history of HIV and hepatitis C infection in 6.38%. 28.21% of patients were maintained on partial exchange transfusions as an outpatient for various indications. 72.73% were on hydroxyurea, 7.5% were on crizanlizumab, 5.26% were on voxelotor and 26.83% were on iron chelation. …”
Publicado 2021
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47730“…Gadolinium-enhanced MRI revealed a 38mm x 20mm x 8mm soft tissue mass within the extraconal compartment of the left orbit, raising the possibility of lymphoma. CT chest, abdomen and pelvis showed no distant metastases. …”
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47731por Dahiya, Sandeep, Saulite, Vera, Kleemann, Frieder, Nagumantry, Sateesh, Bulley, Simon“…She was readmitted two weeks later with recurrence of symptoms, renal impairment, pancytopenia, ferritin >8000mmol/l, raised lactate dehydrogenase and triglycerides. A CT chest, abdomen and pelvis was largely unremarkable. …”
Publicado 2022
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47732“…Rubella IgG was detected, Varicella IgG negative as were Cytomegalovirus, Syphilis and TB testing. He had a normal chest x-ray. The dermatology team diagnosed him with subcutaneous granulomatous annulare, a benign self limiting condition with no indication for biopsy and no treatment required. …”
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47733“…His respiratory status worsened, with increased oxygen demand. A chest X-Ray done showed features of pneumonia and a right sided pleural effusion. …”
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47734“…Six reviews reported on prophylactic interventions for the prevention of PDA and included pharmacological prophylaxis with prostaglandin inhibitor drugs, prophylactic surgical PDA ligation, and non‐pharmacologic interventions (chest shielding during phototherapy and restriction of fluid intake); one review reported on the use of indomethacin for the management of asymptomatic PDA; nine reviews reported on interventions for the management of symptomatic PDA, and included pharmacotherapy with prostaglandin inhibitor drugs in various routes and dosages, surgical PDA ligation, and adjunct therapies (use of furosemide and dopamine in conjunction with indomethacin). …”
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47735por Zadik, Zvi, Zelinska, Nataliya, Iotova, Violeta, Skorodok, Yulia, Malievskiy, Oleg A, Mauras, Nelly, Valluri, Srinivas R, Pastrak, Aleksandra, Rosenfeld, Ron G, Taylor, Carrie T, Nijher, Monica, Roland, Carl, Wang, Ronnie, Wajnrajch, Michael P, Cara, Jose F“…Study drug–related TEAEs occurred in 2 subjects: keeled chest acquired and scoliosis in 1 and arthralgia in 1. …”
Publicado 2023
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47736“…These processes take place more rapidly at room temperature than in the ice chest, and in the incubator than in the room. In the fluid holding the living bacilli we have, therefore, after the first few hours of toxin formation, a double process going on, one of deterioration in the toxin already accumulated, which tends to increase the neutralizing value of the fatal dose, the other of new toxin formation, which probably tends to diminish the neutralizing value. …”
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47737“…ANA, dsDNA and RF were negative; anti-cardiolipin IgM was initially positive, but negative on repeat. CT scan of the chest, abdomen and pelvis (CTCAP) showed diffuse lymphadenopathy, hepatomegaly and mild pericardial effusion. …”
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47738por Eckhardt, Christina M., Cummings, Matthew J., Rajagopalan, Kartik N., Borden, Sarah, Bitan, Zachary C., Wolf, Allison, Kantor, Alex, Briese, Thomas, Meyer, Benjamin J., Jacobson, Samuel D., Scotto, Dawn, Mishra, Nischay, Philip, Neena M., Stotler, Brie A., Schwartz, Joseph, Shaz, Beth, Spitalnik, Steven L., Eisenberg, Andrew, Hod, Eldad A., Justman, Jessica, Cheung, Ken, Lipkin, W. Ian, O’Donnell, Max R.“…PARTICIPANTS: Eligible participants include adults (≥ 18 years) with evidence of SARS-CoV-2 infection by PCR test of nasopharyngeal or oropharyngeal swab within 14 days of randomization, evidence of infiltrates on chest radiography, peripheral capillary oxygen saturation (SpO2) ≤ 94% on room air, and/or need for supplemental oxygen, non-invasive mechanical ventilation, or invasive mechanical ventilation, who are willing and able to provide written informed consent prior to performing study procedures or who have a legally authorized representative available to do so. …”
Publicado 2020
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47739por El-Ghazali, Shawki, Sivalokanathan, Sanjay, Foley, Michael, Ganesaratnam, Inithan, Pearse, Simon, Varnava, Amanda, Malhotra, Aneil, Cole, Graham, Youngstein, Taryn“…ECG showed sinus-rhythm and CT-chest demonstrated lower-lobe consolidation with pleural-effusions. …”
Publicado 2020
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47740por Vonasek, Bryan, Ness, Tara, Takwoingi, Yemisi, Kay, Alexander W, Wyk, Susanna S, Ouellette, Lara, Marais, Ben J, Steingart, Karen R, Mandalakas, Anna M“…OBJECTIVES: To estimate the sensitivity and specificity of the presence of one or more tuberculosis symptoms, or symptom combinations; chest radiography (CXR); Xpert MTB/RIF; Xpert Ultra; and combinations of these as screening tests for detecting active pulmonary childhood tuberculosis in the following groups. – Tuberculosis contacts, including household contacts, school contacts, and other close contacts of a person with infectious tuberculosis. – Children living with HIV. – Children with pneumonia. – Other risk groups (e.g. children with a history of previous tuberculosis, malnourished children). – Children in the general population in high tuberculosis burden settings. …”
Publicado 2021
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