What are the most important unanswered research questions on rapid review methodology? A James Lind Alliance research methodology Priority Setting Partnership: the Priority III stu...

por Beecher, Claire, Toomey, Elaine, Maeso, Beccy, Whiting, Caroline, Stewart, Derek C., Worrall, Andrew, Elliott, Jim, Smith, Maureen, Tierney, Theresa, Blackwood, Bronagh, Maguire, Teresa, Kampman, Melissa, Ling, Benny, Gravel, Christopher, Gill, Catherine, Healy, Patricia, Houghton, Catherine, Booth, Andrew, Garritty, Chantelle, Thomas, James, Tricco, Andrea C., Burke, Nikita N., Keenan, Ciara, Westmore, Matthew, Devane, Declan
Publicado 2021

Long-term Follow-up and Patterns of Response, Progression, and Hyperprogression in Patients after PD-1 Blockade in Advanced Sarcoma

por Klemen, Nicholas D., Hwang, Sinchun, Bradic, Martina, Rosenbaum, Evan, Dickson, Mark A., Gounder, Mrinal M., Kelly, Ciara M., Keohan, Mary L., Movva, Sujana, Thornton, Katherine A., Chi, Ping, Nacev, Benjamin A., Chan, Jason E., Bartlett, Edmund K., Richards, Allison L., Singer, Samuel, Donoghue, Mark T.A., Tap, William D., D'Angelo, Sandra P.
Publicado 2022

Clinical, genomic, and transcriptomic correlates of response to immune checkpoint blockade-based therapy in a cohort of patients with angiosarcoma treated at a single center

por Rosenbaum, Evan, Antonescu, Cristina R, Smith, Shaleigh, Bradic, Martina, Kashani, Daniel, Richards, Allison L, Donoghue, Mark, Kelly, Ciara M, Nacev, Benjamin, Chan, Jason E, Chi, Ping, Dickson, Mark A, Keohan, Mary L, Gounder, Mrinal M, Movva, Sujana, Avutu, Viswatej, Thornton, Katherine, Zehir, Ahmet, Bowman, Anita S, Singer, Samuel, Tap, William, D’Angelo, Sandra
Publicado 2022

Using genetic variation to disentangle the complex relationship between food intake and health outcomes

por Pirastu, Nicola, McDonnell, Ciara, Grzeszkowiak, Eryk J., Mounier, Ninon, Imamura, Fumiaki, Merino, Jordi, Day, Felix R., Zheng, Jie, Taba, Nele, Concas, Maria Pina, Repetto, Linda, Kentistou, Katherine A., Robino, Antonietta, Esko, Tõnu, Joshi, Peter K., Fischer, Krista, Ong, Ken K., Gaunt, Tom R., Kutalik, Zoltán, Perry, John R. B., Wilson, James F.
Publicado 2022

Pulmonary osteoclast-like cells in silica induced pulmonary fibrosis

por Hasegawa, Yoshihiro, Franks, Jennifer M., Tanaka, Yusuke, Uehara, Yasuaki, Read, David F., Williams, Claire, Srivatsan, Sanjay, Pitstick, Lori B., Nikolaidis, Nikolaos M., Shaver, Ciara M., Wu, Huixing, Gardner, Jason C., Osterburg, Andrew R., Yu, Jane J., Kopras, Elizabeth J., Teitelbaum, Steven L., Wikenheiser-Brokamp, Kathryn A., Trapnell, Cole, McCormack, Francis X.
Publicado 2023

Anti-GM-CSF otilimab versus tofacitinib or placebo in patients with active rheumatoid arthritis and an inadequate response to conventional or biologic DMARDs: two phase 3 randomise...

por Fleischmann, Roy M, van der Heijde, Désirée, Strand, Vibeke, Atsumi, Tatsuya, McInnes, Iain B, Takeuchi, Tsutomu, Taylor, Peter C, Bracher, Marguerite, Brooks, David, Davies, John, Goode, Christopher, Gupta, Anubha, Mukherjee, Sumanta, O’Shea, Ciara, Saurigny, Didier, Schifano, Lorrie A, Shelton, Celia, Smith, Julia E, Wang, Millie, Wang, Reena, Watts, Sarah, Weinblatt, Michael E
Publicado 2023

Dissociation of solid tumor tissues with cold active protease for single-cell RNA-seq minimizes conserved collagenase-associated stress responses

por O’Flanagan, Ciara H., Campbell, Kieran R., Zhang, Allen W., Kabeer, Farhia, Lim, Jamie L. P., Biele, Justina, Eirew, Peter, Lai, Daniel, McPherson, Andrew, Kong, Esther, Bates, Cherie, Borkowski, Kelly, Wiens, Matt, Hewitson, Brittany, Hopkins, James, Pham, Jenifer, Ceglia, Nicholas, Moore, Richard, Mungall, Andrew J., McAlpine, Jessica N., Shah, Sohrab P., Aparicio, Samuel
Publicado 2019

An integrated multidisciplinary model of COVID-19 recovery care

por O’Brien, Helen, Tracey, Michael J., Ottewill, Ciara, O’Brien, Michael E., Morgan, Ross K., Costello, Richard W., Gunaratnam, Cedric, Ryan, Daniel, McElvaney, Noel G., McConkey, Samuel J., McNally, Cora, Curley, Gerard F., MacHale, Siobhan, Gillan, Diane, Pender, Niall, Barry, Helen, de Barra, Eoghan, Kiernan, Fiona M., Sulaiman, Imran, Hurley, Killian
Publicado 2020

Evidence to Underpin Vitamin A Requirements and Upper Limits in Children Aged 0 to 48 Months: A Scoping Review

por Hooper, Lee, Esio-Bassey, Chizoba, Brainard, Julii, Fynn, Judith, Jennings, Amy, Jones, Natalia, Tailor, Bhavesh V., Abdelhamid, Asmaa, Coe, Calvin, Esgunoglu, Latife, Fallon, Ciara, Gyamfi, Ernestina, Hill, Claire, Howard Wilsher, Stephanie, Narayanan, Nithin, Oladosu, Titilopemi, Parkinson, Ellice, Prentice, Emma, Qurashi, Meysoon, Read, Luke, Getley, Harriet, Song, Fujian, Welch, Ailsa A., Aggett, Peter, Lietz, Georg
Publicado 2022

The effect of needle length and skin to deltoid muscle distance in adults receiving an mRNA COVID-19 vaccine

por Hills, Thomas, Paterson, Aimee, Woodward, Rebecca, Middleton, Francis, Carlton, Lauren H., McGregor, Reuben, Barfoot, Sebastien, Ramiah, Ciara, Whitcombe, Alana L., Zimbron, Victor M., Mahuika, David, Brown, Joshua, Palmer-Neels, Kate, Manning, Brittany, Jani, Devanshi, Reeves, Brooke, Whitta, Georgia T., Morpeth, Susan, Beasley, Richard, Weatherall, Mark, Jordan, Anthony, McIntyre, Peter, Moreland, Nicole J., Mirjalili, S. Ali
Publicado 2022

Comprehensive Phenotypic Characterization of Late Gadolinium Enhancement Predicts Sudden Cardiac Death in Coronary Artery Disease

por Jones, Richard E., Zaidi, Hassan A., Hammersley, Daniel J., Hatipoglu, Suzan, Owen, Ruth, Balaban, Gabriel, de Marvao, Antonio, Simard, François, Lota, Amrit S., Mahon, Ciara, Almogheer, Batool, Mach, Lukas, Musella, Francesca, Chen, Xiuyu, Gregson, John, Lazzari, Laura, Ravendren, Andrew, Leyva, Francisco, Zhao, Shihua, Vazir, Ali, Lamata, Pablo, Halliday, Brian P., Pennell, Dudley J., Bishop, Martin J., Prasad, Sanjay K.
Publicado 2023

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection

por Ghorbani, Peyman, Kim, Sang Yong, Smith, Tyler K. T., Minarrieta, Lucía, Robert-Gostlin, Victoria, Kilgour, Marisa K., Ilijevska, Maja, Alecu, Irina, Snider, Shayne A., Margison, Kaitlyn D., Nunes, Julia R. C., Woo, Daniel, Pember, Ciara, O’Dwyer, Conor, Ouellette, Julie, Kotchetkov, Pavel, St-Pierre, Julie, Bennett, Steffany A. L., Lacoste, Baptiste, Blais, Alexandre, Nair, Meera G., Fullerton, Morgan D.
Publicado 2023

THU156 Significantly Improved Annual Height Velocity With Once-Weekly TransCon CNP In Children With Achondroplasia: The ACcomplisH Phase 2, Randomized, Double-Blind, Placebo-Contro...

por Savarirayan, Ravi, McDonnell, Ciara, Hoernschemeyer, Daniel G, Hove, Hanne B, Zarate, Yuri A, Bober, Michael B, Bacino, Carlos A, Legare, Janet M, Högler, Wolfgang, Quattrin, Teresa, Abuzzahab, M Jennifer, Hofman, Paul L, White, Klane K, Ma, Nina, Schnabel, Dirk, Sousa, Sérgio B, Fan, Xiaolin, Chakraborty, Mukta, Giwa, Adebola, Smith, Sharon E, Volck, Birgitte, Shu, Aimee D
Publicado 2023

Once-weekly TransCon CNP (navepegritide) in children with achondroplasia (ACcomplisH): a phase 2, multicentre, randomised, double-blind, placebo-controlled, dose-escalation trial

por Savarirayan, Ravi, Hoernschemeyer, Daniel G., Ljungberg, Merete, Zarate, Yuri A., Bacino, Carlos A., Bober, Michael B., Legare, Janet M., Högler, Wolfgang, Quattrin, Teresa, Abuzzahab, M. Jennifer, Hofman, Paul L., White, Klane K., Ma, Nina S., Schnabel, Dirk, Sousa, Sérgio B., Mao, Meng, Smith, Alden, Chakraborty, Mukta, Giwa, Adebola, Winding, Bent, Volck, Birgitte, Shu, Aimee D., McDonnell, Ciara
Publicado 2023

Patient-Reported Outcomes among Multiple Myeloma Patients Treated with Standard of Care Idecabtagene Vicleucel

por Oswald, Laura B., Gudenkauf, Lisa M., Li, Xiaoyin, De Avila, Gabriel, Peres, Lauren C., Kirtane, Kedar, Gonzalez, Brian D., Hoogland, Aasha I., Nguyen, Oanh, Rodriguez, Yvelise, Baz, Rachid C., Shain, Kenneth H., Alsina, Melissa, Locke, Frederick L., Freeman, Ciara, Castaneda Puglianini, Omar, Nishihori, Taiga, Liu, Hien, Blue, Brandon, Grajales-Cruz, Ariel, Jim, Heather S. L., Hansen, Doris K.
Publicado 2023

Deep-Learning for Epicardial Adipose Tissue Assessment With Computed Tomography: Implications for Cardiovascular Risk Prediction

por West, Henry W., Siddique, Muhammad, Williams, Michelle C., Volpe, Lucrezia, Desai, Ria, Lyasheva, Maria, Thomas, Sheena, Dangas, Katerina, Kotanidis, Christos P., Tomlins, Pete, Mahon, Ciara, Kardos, Attila, Adlam, David, Graby, John, Rodrigues, Jonathan C.L., Shirodaria, Cheerag, Deanfield, John, Mehta, Nehal N., Neubauer, Stefan, Channon, Keith M., Desai, Milind Y., Nicol, Edward D., Newby, David E., Antoniades, Charalambos
Publicado 2023

A Role for TLR4 in Clostridium difficile Infection and the Recognition of Surface Layer Proteins

por Ryan, Anthony, Lynch, Mark, Smith, Sinead M., Amu, Sylvie, Nel, Hendrik J., McCoy, Claire E., Dowling, Jennifer K., Draper, Eve, O'Reilly, Vincent, McCarthy, Ciara, O'Brien, Julie, Ní Eidhin, Déirdre, O'Connell, Mary J., Keogh, Brian, Morton, Charles O., Rogers, Thomas R., Fallon, Padraic G., O'Neill, Luke A., Kelleher, Dermot, Loscher, Christine E.
Publicado 2011

Anti-estrogen Resistance in Human Breast Tumors Is Driven by JAG1-NOTCH4-Dependent Cancer Stem Cell Activity

por Simões, Bruno M., O’Brien, Ciara S., Eyre, Rachel, Silva, Andreia, Yu, Ling, Sarmiento-Castro, Aida, Alférez, Denis G., Spence, Kath, Santiago-Gómez, Angélica, Chemi, Francesca, Acar, Ahmet, Gandhi, Ashu, Howell, Anthony, Brennan, Keith, Rydén, Lisa, Catalano, Stefania, Andó, Sebastiano, Gee, Julia, Ucar, Ahmet, Sims, Andrew H., Marangoni, Elisabetta, Farnie, Gillian, Landberg, Göran, Howell, Sacha J., Clarke, Robert B.
Publicado 2015

Functional Antagonism of Junctional Adhesion Molecule-A (JAM-A), Overexpressed in Breast Ductal Carcinoma In Situ (DCIS), Reduces HER2-Positive Tumor Progression

por Smith, Yvonne E., Wang, Guannan, Flynn, Ciara L., Madden, Stephen F., MacEneaney, Owen, Cruz, Rodrigo G. B., Richards, Cathy E., Jahns, Hanne, Brennan, Marian, Cremona, Mattia, Hennessy, Bryan T., Sheehan, Katherine, Casucci, Alexander, Sani, Faizah A., Hudson, Lance, Fay, Joanna, Vellanki, Sri H., O’Flaherty, Siobhan, Devocelle, Marc, Hill, Arnold D. K., Brennan, Kieran, Sukumar, Saraswati, Hopkins, Ann M.
Publicado 2022

DNAJC30 defect: a frequent cause of recessive Leber hereditary optic neuropathy and Leigh syndrome

por Stenton, Sarah L., Tesarova, Marketa, Sheremet, Natalia L., Catarino, Claudia B., Carelli, Valerio, Ciara, Elżbieta, Curry, Kathryn, Engvall, Martin, Fleming, Leah R., Freisinger, Peter, Iwanicka-Pronicka, Katarzyna, Jurkiewicz, Elżbieta, Klopstock, Thomas, Koenig, Mary K., Kolářová, Hana, Kousal, Bohdan, Krylova, Tatiana, La Morgia, Chiara, Nosková, Lenka, Piekutowska-Abramczuk, Dorota, Russo, Sam N., Stránecký, Viktor, Tóthová, Iveta, Träisk, Frank, Prokisch, Holger
Publicado 2022