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181“…Clostridium botulinum neurotoxins (BoNTs) cause flaccid paralysis through inhibition of acetylcholine release from motor neurons; however, at tiny doses, this property is exploited for use as a therapeutic. …”
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182“…Botulinum toxin (BoNT) is a neurotoxin produced by the Clostridium botulinum bacteria. Among seven different isoforms, only BoNT-A and BoNT-B are commercially used. …”
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183por Montville, Thomas J.Tabla de Contenidos: “…Trajectory of food microbiology -- Factors that influence microbes in foods -- Spores and their significance -- Detection and enumeration of microbes in food -- Rapid and automated microbial methods -- Indicator microorganisms and microbiological criteria -- Salmonella species -- Campylobacter jejuni -- Enterohemorrhagic Escherichia coli -- Yersinia enterocolitica -- Shigella species -- Vibrio species -- Listeria monocytogenes -- Staphylococcus aureus -- Clostridium botulinum -- Clostridium perfringens -- Bacillus cereus -- Lactic acid bacteria and food fermentations -- Yeast-based and other fermentations -- Spoilage organisms -- Molds -- Viruses and prions -- Antimicrobial preservatives -- Biologically based preservation and probiotic bacteria -- Physical methods of food preservation -- Industrial strategies for ensuring safe food.…”
Publicado 2008
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184por Delgado, Josué, Álvarez, Micaela, Cebrián, Eva, Martín, Irene, Roncero, Elia, Rodríguez, Mar“…Together with this beneficial microbiota, both pathogenic and toxigenic microorganisms such as Listeria monocytogenes, Salmonella enterica, Staphylococcus aureus, Clostridium botulinum, Escherichia coli, Candida spp., Penicillium spp. and Aspergillus spp., can contaminate these products and pose a risk for the consumers. …”
Publicado 2023
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185“…Pathogens such as Listeria monocytogenes, Clostridium botulinum, and Bacillus cereus are naturally present in some soil, and their presence on fresh produce is not rare. …”
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186por Hutchison, Janine R., Dukovcic, Stephanie R., Dierksen, Karen P., Carlyle, Calvin A., Caldwell, Bruce A., Trempy, Janine E.“…Erythrophore cells were exposed to Salmonella enteritidis, Clostridium perfringens and Clostridium botulinum. Each bacterial pathogen elicited a response from erythrophore cells that was distinguished from the corresponding bacterial growth medium, and this observed response was unique for each bacterial pathogen. …”
Publicado 2008
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187por Stiles, Bradley G., Pradhan, Kisha, Fleming, Jodie M., Samy, Ramar Perumal, Barth, Holger, Popoff, Michel R.“…These Gram-positive bacteria and their toxins include Clostridium botulinum (C2 toxin), Clostridium difficile (C. difficile toxin or CDT), Clostridium perfringens (ι-toxin and binary enterotoxin, or BEC), Clostridium spiroforme (C. spiroforme toxin or CST), as well as Bacillus cereus (vegetative insecticidal protein or VIP). …”
Publicado 2014
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188“…Botulinum neurotoxin A (BoNT-A), derived from Clostridium botulinum, has been used clinically for several diseases or syndrome including chronic migraine, spasticity, focal dystonia and other neuropathic pain. …”
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189“…Botulinum toxin (BTX) is a neurotoxic protein produced by Clostridium botulinum, an anaerobic bacterium. BTX therapy is a safe and effective treatment when used for functional silencing of the salivary glands in disorders such as sialoceles and salivary fistulae that may have a post-traumatic or post-operative origin. …”
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190“…Special emphasis is given to toxins falling into a group of selected agents, according to the Centers for Disease Control and Prevention, such as Staphylococcal enterotoxins, Bacillus anthracis toxins, Clostridium botulinum toxins, Clostridium perfringens epsilon toxin, ricin from Ricinus communis, Abrin from Abrus precatorius or control of trade in dual-use items in the European Union, including lesser known protein toxins such as Viscumin from Viscum album. …”
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191“…Starting in the 1950s, a single-species taxonomy where any bacterium producing BoNT would be designated Clostridium botulinum was introduced. As the extreme diversity of these strains was recognized, a secondary system of taxonomic “groups” evolved. …”
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192Atomic force microscopic image data of botulinum neurotoxin complexes with different molecular sizespor Miyashita, Shin-Ichiro, Sagane, Yoshimasa, Uchino, Takamasa, Karatsu, Shura, Hosoya, Keita, Huang, Ihsun, Niwa, Koichi, Watanabe, Toshihiro, Niimura, Yoichi, Suzuki, Tomonori“…This data article provides atomic force microscopy (AFM) amplitude images of botulinum toxin complex (TC) molecules produced by Clostridium botulinum serotype D strain. C. botulinum produces different-sized TC molecules, such as a complex of botulinum neurotoxin and nontoxic nonhemagglutinin proteins (M-TC) and complex of M-TC and hemagglutinin subcomplex (L-TC). …”
Publicado 2019
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193por da Fonseca, Lucas José Sá, de Carvalho, Diogo Couto, de Moraes, Helena Providelli, Feitosa, Izabela Dayany França, Pereira, Gil, Vilela, Rodrigo Vasconcellos, Fernandes, Breno Franco Silveira, Gomez, Rodrigo Santiago, Nobre, Vandack“…Representing the rarest form of botulism presentation in clinical practice, this infectious disease may have developed due to a cluster of predisposing factors that favored Clostridium botulinum colonization and the endogenous production of neurotoxins, among which are previous use of broad-spectrum antibiotics and colon changes related to the development of the neoplasia. …”
Publicado 2019
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194por Zaragoza, Nicolas E., Orellana, Camila A., Moonen, Glenn A., Moutafis, George, Marcellin, Esteban“…This review discusses the toxins, diseases, and toxoid production processes of the most common pathogenic Clostridium species, including Clostridium botulinum, Clostridium tetani, Clostridium perfringens, Clostridium chauvoei, Clostridium septicum, Clostridium novyi and Clostridium hemolyticum.…”
Publicado 2019
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195“…Botulinum toxins are neurotoxic modular proteins composed of a heavy chain and a light chain connected by a disulfide bond and are produced by Clostridium botulinum. Although lethally toxic, botulinum toxin in low doses is clinically effective in numerous medical conditions, including muscle spasticity, strabismus, hyperactive urinary bladder, excessive sweating, and migraine. …”
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196“…Nitrites impart a better flavor, taste and aroma; preserve the red-pinkish color of the meat; and prevent the risk of bacterial contamination of the cured meat, especially from Clostridium botulinum. Unfortunately, recent research has demonstrated some negative effects of this technique. …”
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197por Martina, Emanuela, Diotallevi, Federico, Radi, Giulia, Campanati, Anna, Offidani, Annamaria“…Botulinum toxin is a superfamily of neurotoxins produced by the bacterium Clostridium Botulinum with well-established efficacy and safety profile in focal idiopathic hyperhidrosis. …”
Publicado 2021
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198por Ghantarchyan, Henrik, Phan, Alexander T, Hu, Janie, Thaker, Kunal, Dombrovsky, Inessa, Roloff, Kristina, Arabian, Sarkis“…Botulism is a rare neuroparalytic illness caused by Clostridium botulinum that can manifest as a descending flaccid paralysis, progressing from cranial neuropathies to respiratory failure. …”
Publicado 2022
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199por Rocha, João Miguel, Kovacevik, Biljana, Veličkovska, Sanja Kostadinović, Tamame, Mercedes, Teixeira, José António“…Pathogenic and spoilage bacteria are usually Gram-negative, although there are some Gram-positive ones, such as Listeria monocytogenes, Clostridium botulinum, and C. perfringens. Some may merely cause spoilage, while others may be related to foodborne illnesses.…”
Publicado 2023
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200por Pinna, Luigia, Coccollone, Annamaria, Maxia, Marcella, Bano, Luca, Scalfaro, Concetta, Mandas, Daniela, Liciardi, Manuele“…We emphasize the importance of the early sampling of food and biological matrixes in cases of suspected botulism to arrive at a quick diagnosis. ABSTRACT: Clostridium botulinum is the main causative agent of botulism in humans and animals. …”
Publicado 2023
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