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Mostrando 381 - 400 Resultados de 426 Para Buscar '"Clostridium botulinum"', tiempo de consulta: 0.18s Limitar resultados
  1. 381
    “…The C3 exoenzyme from Clostridium botulinum could be a potential new candidate for the protection and regeneration of SGN. …”
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    Potentiation of Brain-Derived Neurotrophic Factor-Induced Protection of Spiral Ganglion Neurons by C3 Exoenzyme/Rho Inhibitor
  2. 382
    “…The most important biological hazards in feed are Salmonella, Enterobacteriaceae, pathogenic Escherichia coli, Staphylococcus aureus, Listeria monocytogenes, Clostridium perfringens, Clostridium botulinum, Aeromonas, and Campylobacter. Other biological hazards of feed are the mycotoxin-producing molds. …”
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    Microbiological Hazards in Dry Dog Chews and Feeds
  3. 383
    “…Botulism is a rare, life-threatening paralytic disease caused by Clostridium botulinum neurotoxin (BoNT). Available treatments, including an equine antitoxin and human immune globulin, are given postexposure and challenging to produce and administer. …”
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    Safety, Tolerability, and Pharmacokinetics of NTM-1632, a Novel Mixture of Three Monoclonal Antibodies against Botulinum Toxin B
  4. 384
    “…Botulinum neurotoxin (BoNT), produced by Clostridium botulinum, is generally known to be the most poisonous of all biological toxins. …”
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    Intratracheal inoculation of AHc vaccine induces protection against aerosolized botulinum neurotoxin A challenge in mice
  5. 385
    por Learoyd, T
    Publicado 2022
    “…BACKGROUND: Botulism is a rare illness caused by Clostridium botulinum toxin with a naïve case fatality ratio of 40-50%. …”
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    Linear pathway analysis of European botulism poisoning response guidelines
  6. 386
    “…RESULTS: The strains were identified as group I proteolytic Clostridium botulinum, with BoNTB responsible for the outbreak. …”
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    From genome inspection to clinical significance: source attribution of a foodborne botulism outbreak
  7. 387
    “…The presence of ERα was then detected by immunocytochemistry in either the nuclei or the cytoplasms of MCF-7 cells. Finally, Clostridium botulinum C3 exoenzyme treatment was used to determine the involvement of Rho proteins in ERE-dependent luciferase activity. …”
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    Prenylation inhibitors stimulate both estrogen receptor α transcriptional activity through AF-1 and AF-2 and estrogen receptor β transcriptional activity
  8. 388
    “…The seven antigenically distinct serotypes of Clostridium botulinum neurotoxins, the causative agents of botulism, block the neurotransmitter release by specifically cleaving one of the three SNARE proteins and induce flaccid paralysis. …”
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    Substrate Binding Mode and Its Implication on Drug Design for Botulinum Neurotoxin A
  9. 389
    “…BACKGROUND: Clostridium botulinum, an obligate anaerobic spore-forming bacterium, produces seven antigenic variants of botulinum toxin that are distinguished serologically and termed "serotypes". …”
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    Universal and specific quantitative detection of botulinum neurotoxin genes
  10. 390
    por Weininger, Arthur, Weininger, Susan
    Publicado 2015
    “…In N11 protein, we identified hepatitis E E2S-like domains, SARS spike protein-like domains, and toxin components shared by alpha-bungarotoxin, staphylococcal enterotoxin I, anthrax lethal factor, clostridium botulinum neurotoxin, and clostridium tetanus toxin. …”
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    Using Common Spatial Distributions of Atoms to Relate Functionally Divergent Influenza Virus N10 and N11 Protein Structures to Functionally Characterized Neuraminidase Structures, Toxin Cell Entry Domains, and Non-Influenza Virus Cell Entry Domains
  11. 391
    “…Botulism is a rare but severe neurological disease in man and animals that is caused by botulinum neurotoxins (BoNTs) produced by Clostridium botulinum and atypical strains from other Clostridium and non-Clostridium species. …”
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    Public Health Risk Associated with Botulism as Foodborne Zoonoses
  12. 392
    “…We have carried out a comparative screening of two antibody libraries, a semi-synthetic scFv library and a human-derived Fab library against the protective antigen toxin component of Bacillus anthracis and the epsilon toxin of Clostridium botulinum. We have shown that while the synthetic library produced a diverse collection of specific scFv-phage, these contained a high frequency of unnatural amber stops and glycosylation sites which limited their conversion to IgG, and also a high number which lost specificity when expressed as IgG. …”
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    Comparison of the efficiency of antibody selection from semi-synthetic scFv and non-immune Fab phage display libraries against protein targets for rapid development of diagnostic immunoassays
  13. 393
    “…Listeria monocytogenes, Aeromonas spp. and non‐proteolytic Clostridium botulinum), is expected to be < 0.2 log(10) units higher in tubs than in boxes after 3 days when the initial temperature of the fish is 0°C (‘keeping’ process). …”
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    The use of the so‐called ‘tubs’ for transporting and storing fresh fishery products
  14. 394
    “…Clostridia are a class of Gram-positive, anaerobic and spore-forming bacteria and include the important human pathogens Clostridium perfringens, Clostridium botulinum and Clostridioides difficile, among numerous others. …”
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    Identification of the Clostridial cellulose synthase and characterization of the cognate glycosyl hydrolase, CcsZ
  15. 395
    “…Binary enterotoxins Clostridioides difficile CDT toxin, Clostridium botulinum C2 toxin, and Clostridium perfringens iota toxin consist of two separate protein components. …”
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    Intoxication of mammalian cells with binary clostridial enterotoxins is inhibited by the combination of pharmacological chaperone inhibitors
  16. 396
    “…These samples were analyzed using real-time PCR after an enrichment step to detect Clostridium botulinum type D/C. The results showed contamination in the manure from the broilers raised just before the onset of the cattle outbreak (5 + /5), as well as in some of the components of the cattle ration (3 + /17). …”
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    Asymptomatic Carriage of C. botulinum Type D/C in Broiler Flocks as the Source of Contamination of a Massive Botulism Outbreak on a Dairy Cattle Farm
  17. 397
    “…BACKGROUND: Clostridium botulinum remains a major threat to a select population of subcutaneous and intramuscular drug users. …”
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    Early diagnosis and critical management of wound botulism in the emergency department: a single center experience and literature review
  18. 398
    “…Classified as the genospecies Clostridium novyi sensu lato and distributed into four lineages (I–IV), Clostridium botulinum (group III), Clostridium novyi, and Clostridium haemolyticum are clostridial pathogens that cause animal diseases. …”
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    Exploration of the Diversity of Clustered Regularly Interspaced Short Palindromic Repeats-Cas Systems in Clostridium novyi sensu lato
  19. 399
    “…BACKGROUND: PrabotulinumtoxinA is a 900-kDa botulinum toxin type A produced by Clostridium botulinum. OBJECTIVES: The authors sought to investigate the safety of prabotulinumtoxinA for treatment of glabellar lines. …”
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    The First of Two One-Year, Multicenter, Open-Label, Repeat-Dose, Phase II Safety Studies of PrabotulinumtoxinA for the Treatment of Moderate to Severe Glabellar Lines in Adult Patients
  20. 400
    “…According to the CDC classification, Bacillus anthracis and Clostridium botulinum, the bacterial pathogens that cause anthrax and botulism, respectively, are considered to be the most dangerous potential biological agents. …”
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    A multipathogen DNA vaccine elicits protective immune responses against two class A bioterrorism agents, anthrax and botulism
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