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62“…Clostridium botulinum causes severe foodborne intoxications by producing a potent neurotoxin. …”
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63por Kruemmel, Ana Rafaela, Halpin, Jessica L., Foltz, Victoria, Dykes, Janet, Lúquez, Carolina“…Here, we report the draft genome sequence of Clostridium botulinum strain CDC76130, which harbors a rare botulinum toxin gene (bont) complex arrangement of bont/A5 and truncated bont/B2 within the same ha toxin gene cluster.…”
Publicado 2022
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64por Chen, Bao-Chung, Huang, Yao-Ching, Huang, Shi-Hao, Yu, Pi-Ching, Wang, Bing-Long, Lin, Fu-Huang, Chou, Yu-Ching, Hsieh, Chi-Jeng, Yu, Chia-Peng“…Botulinum toxin is produced by Clostridium botulinum, a gram-positive anaerobic bacterium. …”
Publicado 2022
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65por Fellermann, Maximilian, Stemmer, Mia, Noschka, Reiner, Wondany, Fanny, Fischer, Stephan, Michaelis, Jens, Stenger, Steffen, Barth, Holger“…The protein toxin C3bot from Clostridium botulinum is a mono-ADP-ribosyltransferase that selectively intoxicates monocyte-derived cells such as macrophages, osteoclasts, and dendritic cells (DCs) by cytosolic modification of Rho-A, -B, and -C. …”
Publicado 2022
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66por Pellett, Sabine, Tepp, William H., Bradshaw, Marite, Kalb, Suzanne R., Dykes, Janet K., Lin, Guangyun, Nawrocki, Erin M., Pier, Christina L., Barr, John R., Maslanka, Susan E., Johnson, Eric A.“…This novel BoNT was produced together with BoNT/B2 in a dual-toxin-producing Clostridium botulinum strain. The data used to designate this novel toxin as a new serotype were derived from culture supernatant containing both BoNT/B2 and novel toxin and from sequence information, although data from two independent laboratories indicated neutralization by antibodies raised against BoNT/A1, and classification as BoNT/FA was proposed. …”
Publicado 2016
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67por Woudstra, Cédric, Le Maréchal, Caroline, Souillard, Rozenn, Bayon-Auboyer, Marie-Hélène, Mermoud, Isabelle, Desoutter, Denise, Fach, Patrick“…Animal botulism is caused by group III Clostridium botulinum strains producing type C and D toxins, or their chimeric forms C/D and D/C. …”
Publicado 2016
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68“…The activity of the esterase (Cbotu_EstA) from Clostridium botulinum on the polyester poly(ethylene terephthalate) (PET) was improved by concomitant engineering of two different domains. …”
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69por Sudha, Rati, Katiyar, Amit, Katiyar, Poonam, Singh, Harpreet, Prasad, Purushottam“…A subtractive genomic approach has been utilized for the identification of potential drug targets and vaccine candidates in Clostridium botulinum, the causative agent of flaccid paralysis in humans. …”
Publicado 2019
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70por Le Gratiet, Thibault, Poezevara, Typhaine, Rouxel, Sandra, Houard, Emmanuelle, Mazuet, Christelle, Chemaly, Marianne, Le Maréchal, Caroline“…Avian botulism is a serious neuroparalytic disease mainly caused by a type C/D botulinum neurotoxin produced by Clostridium botulinum group III, one of the entwined bacterial species from the Clostridium novyi sensu lato genospecies. …”
Publicado 2020
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71“…Clostridium botulinum is a Gram-positive, spore-forming anaerobic bacterium that produces botulinum neurotoxin (BoNT). …”
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72por Mertaoja, Anna, Nowakowska, Maria B., Mascher, Gerald, Heljanko, Viivi, Groothuis, Daphne, Minton, Nigel P., Lindström, Miia“…The spores of Clostridium botulinum Group II strains pose a significant threat to the safety of modern packaged foods due to the risk of their survival in pasteurization and their ability to germinate into neurotoxigenic cultures at refrigeration temperatures. …”
Publicado 2021
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73
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74“…Clostridium botulinum C2 toxin is a clostridial binary toxin consisting of actin ADP-ribosyltransferase (C2I) and C2II binding components. …”
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75“…BACKGROUND: Clostridium botulinum strains can be divided into four physiological groups that are sufficiently diverged to be considered as separate species. …”
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77por Gil, Luciana A. F., da Cunha, Carlos Eduardo P., Moreira, Gustavo M. S. G., Salvarani, Felipe M., Assis, Ronnie A., Lobato, Francisco Carlos F., Mendonça, Marcelo, Dellagostin, Odir A., Conceição, Fabricio R.“…Bovine botulism is a fatal disease that is caused by botulinum neurotoxins (BoNTs) produced by Clostridium botulinum serotypes C and D and that causes great economic losses, with nearly 100% lethality during outbreaks. …”
Publicado 2013
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79por Masuyer, Geoffrey, Davies, Jonathan R., Moore, Kevin, Chaddock, John A., Ravi Acharya, K.“…The botulinum neurotoxin type D is one of seven highly potent toxins produced by Clostridium botulinum which inhibit neurotransmission at cholinergic nerve terminals. …”
Publicado 2015
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80por Janganan, Thamarai K., Mullin, Nic, Tzokov, Svetomir B., Stringer, Sandra, Fagan, Robert P., Hobbs, Jamie K., Moir, Anne, Bullough, Per A.“…Clostridium sporogenes is a non-pathogenic close relative and surrogate for Group I (proteolytic) neurotoxin-producing Clostridium botulinum strains. The exosporium, the sac-like outermost layer of spores of these species, is likely to contribute to adhesion, dissemination, and virulence. …”
Publicado 2016
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