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  1. 2221
    por Luengo, Olga, Cardona, Victòria
    Publicado 2014
    “…This review does not intend to comprehensively analyze all the available allergen molecules, but to provide some practical clues on use and interpretation of molecular allergy diagnosis. …”
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    Component resolved diagnosis: when should it be used?
  2. 2222
    “…This work illustrates the importance of charge to the thermodynamics of binding of agonists and antagonists to AMPA receptors and provides clues for further drug discovery.…”
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    Thermodynamics and Mechanism of the Interaction of Willardiine Partial Agonists with a Glutamate Receptor: Implications for Drug Development
  3. 2223
    “…We report a rare case of EMP of the carotid space, describing the imaging features and the differential diagnoses with clues pointing to this rare entity.…”
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    Extramedullary plasmacytoma in the carotid space: Expanding the differential diagnosis
  4. 2224
    “…The understanding of such microbiota at molecular level provides vital clues for the biological control of this devastating pest. …”
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    Seasonally variable intestinal metagenomes of the red palm weevil (Rhynchophorus ferrugineus)
  5. 2225
    por Shimizu, Toru
    Publicado 2013
    “…X-ray crystal structures and spectroscopic and catalytic characterization of the wild-type and mutant proteins have provided important structural and functional clues to understanding the molecular mechanism of intramolecular catalytic regulation by O(2) binding. …”
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    The Heme-Based Oxygen-Sensor Phosphodiesterase Ec DOS (DosP): Structure-Function Relationships
  6. 2226
    “…These findings may be a set of clues to the full understanding of the metastatic process as well as the metastatic acceleration by anti-angiogenic reagents observed in preclinical studies.…”
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    Endothelial cell-initiated extravasation of cancer cells visualized in zebrafish
  7. 2227
    “…The readily crystallizable nature of these proteins was invaluable to provide clues for the observed spectroscopic behavior that results from single mutation of key residues.…”
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    “Turn-On” Protein Fluorescence: In Situ Formation of Cyanine Dyes
  8. 2228
    “…Nonresolving thigh and groin abscesses should lead to the evaluation of the gastrointestinal tract as origin. Diagnostic clues may also be provided by culture reports what as happened in this case.…”
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    Retroperitoneal Perforation of the Appendix Presenting as a Right Thigh Abscess
  9. 2229
    por Giberson, Mariah, Hayes, Robert
    Publicado 2015
    “…The use of beta-blockers as treatment offers clues into the pathogenesis of infantile hemangioma, which is not yet completely understood…”
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    Infantile Hemangioma in a V2 Distribution: Treatment with Nadolol
  10. 2230
    “…The histopathological evaluation also gave no definite clues to the aetiology of the inflammation. Treatment with acyclovir was ineffective, but gancyclovir therapy caused spectacular clinical improvement and healing of erosions. …”
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    Severe viral oesophagitis, pharyngitis, and stomatitis as antecedents of ileocecal Crohn's disease
  11. 2231
    “…We combine this set of clues using a Bayesian classifier that reports the likelihood of an interaction and obtain significantly improved prediction performance when compared to individual sources of evidence and to previously reported algorithms. …”
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    Predicting Peptide-Mediated Interactions on a Genome-Wide Scale
  12. 2232
    por Gyon, Yun Hee, Han, Heon-Seok
    Publicado 2015
    “…In addition to relative bradycardia despite impending cardiac tamponade, short stature, overweight, and hypercholesterolemia were clues for suspected hypothyroidism. During thyroxine supplementation, catch-up growth was incomplete by rapid skeletal maturation. …”
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    Massive pericardial effusion and short stature caused by autoimmune hypothyroidism in a 9-year-old girl
  13. 2233
    “…We hence sequenced the genome of RKS2983 for clues of genomic events that might have led to the divergence and speciation of Salmonella into distinct lineages with diverse host ranges and pathogenic features. …”
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    Complete genome sequence of Salmonella enterica subspecies arizonae str. RKS2983
  14. 2234
    “…We experienced a case of a 70-year-old woman with acute abdomen, which was found to be peritonitis caused by spontaneous gallbladder perforation that was devoid of clues suggesting this condition. Although rare and unusual, this case shows that this disorder should be considered in elderly patients presenting with peritonitis with an unknown etiology.…”
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    A Case of Spontaneous Gallbladder Perforation
  15. 2235
    “…Recent advancement in omics technologies combined with the integrative experimental and clinical validations has provided an insight into the underlying mechanism of CCA initiation and progression as well as clues towards novel biomarkers. This work highlights the discovery and validation of molecular markers in CCA identified through omics approaches. …”
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    An Omics Perspective on Molecular Biomarkers for Diagnosis, Prognosis, and Therapeutics of Cholangiocarcinoma
  16. 2236
    “…In addition, we discussed current immunotherapeutic approaches targeting Aβ to give some clues for exploring the more potentially efficient drugs for treatment of AD.…”
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    β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease
  17. 2237
    “…The skeletal remains of EP-III-4-No.107 from the Eunpyeong site, although incomplete and fragmented, provide important clues to the paleopathological diagnosis of skeletal dysplasias.…”
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    Paleopathological Study of Dwarfism-Related Skeletal Dysplasia in a Late Joseon Dynasty (South Korean) Population
  18. 2238
    por Luo, Fen, Sun, Jiangfeng, Hou, Shouming
    Publicado 2015
    “…Nowadays medical imaging has played an important role in clinical use, which provide important clues for medical diagnosis. In medical image fusion, the extraction of some fine details and description is critical. …”
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    Medical Images Fusion with Patch Based Structure Tensor
  19. 2239
    “…Postmortem exam revealed acute hemorrhagic necrosis of a segment of jejunum secondary to volvulus. Clinical clues suggesting presentations of small bowel volvulus are usually nonspecific; the diagnosis is typically confirmed at surgery. …”
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    A Fatal Twist: Volvulus of the Small Intestine in a 46-Year-Old Woman
  20. 2240
    por Niu, Li
    Publicado 2015
    “…Among a few available tools to address this specific question for making better 2,3-BDZs, perhaps the best one is to use mechanistic clues from studies of the existing antagonists to design and discover more selective and more potent antagonists. …”
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    Mechanism-based design of 2,3-benzodiazepine inhibitors for AMPA receptors
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