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2281“…There was symmetrical bilateral macular involvement and changes on macular electroretinography, which provided clues to the diagnosis of toxic maculopathy. After cessation of sertraline therapy, the retinal pathology reversed with improvement in visual acuity. …”
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2282por Zhou, Huiwei, Liu, Zhuang, Ning, Shixian, Yang, Yunlong, Lang, Chengkun, Lin, Yingyu, Ma, Kun“…The proposed MNM captures important context clues related to knowledge representations learned from knowledge bases. …”
Publicado 2018
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2283por Gordon, Harold W.“…Neurobiological differences between the hemispheres and among various brain structures could provide clues to the specific effect of drugs. Increased attention to this gap in research will give additional insights into the etiology of drug abuse and provide direction for treatment.…”
Publicado 2018
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2284“…These findings, beside the canonical and widely known nuclear activity of SAGA complex in chromatin regulation, provide novel clues on promising aspects linking evolutionary conserved epigenetic factors to the re-programmed metabolism of cancer cells.…”
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2285“…The presence of imaging findings such as T2 hypointensity, irregular frond-like margins, and absence of choline peak may be the clues, which suggest a fungal etiology.…”
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2286por Chebihi, Z. Takki, Belkhayat, A., Chadli, E., Hessissen, L., El Khorassani, M., El Kababri, M., Kili, A., Khattab, M., Bakri, Y., Dakka, N.“…The presence of recurring chromosomal abnormalities (either numeral or structural rearrangements) provides immediate clues to the genetic events leading to leukemia and many abnormalities have important prognostic significance. …”
Publicado 2018
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2287por Li, Zhiyong, Wang, Yifeng, Bello, Babatunde Kazeem, Ajadi, Abolore Adijat, Tong, Xiaohong, Chang, Yuxiao, Zhang, Jian“…The current study provides an overall view of the acetylation events in rice tissues, as well as clues to reveal the function of PKA proteins in physiologically-relevant tissues.…”
Publicado 2018
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2288por Uminski, Kelsey, Kadkhoda, Kamran, Houston, Brett L., Lopez, Alison, MacKenzie, Lauren J., Lindsay, Robbin, Walkty, Andrew, Embil, John, Zarychanski, Ryan“…The presence of leukopenia, thrombocytopenia, and mild hepatic injury are frequently noted on laboratory investigations, which can be important diagnostic clues in attaining an appropriate diagnosis. Herein we present three cases of HGA, highlighting the spectrum of disease by which HGA can manifest. …”
Publicado 2018
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2289por Yamaguchi, Nanaka, Mano, Tatsuo, Ohtomo, Ryo, Ishiura, Hiroyuki, Almansour, M. Asem, Mori, Harushi, Kanda, Junko, Shirota, Yuichiro, Taira, Kenichiro, Morikawa, Teppei, Ikemura, Masako, Yanagi, Yasuo, Murayama, Shigeo, Shimizu, Jun, Sakurai, Yasuhisa, Tsuji, Shoji, Iwata, Atsushi“…While characteristic neuroimaging and skin biopsy findings are important clues to the diagnosis, autopsy studies are still important for confirming the exact disease features. …”
Publicado 2018
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2290por Denis, Antonia, Martínez-Núñez, Mario Alberto, Tenorio-Salgado, Silvia, Perez-Rueda, Ernesto“…These analyses increase our knowledge about gene regulation in P. furiosus DSM 3638 and provide additional clues for comprehensive modeling of transcriptional regulatory networks in the Archaea cellular domain.…”
Publicado 2018
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2291“…The ultimate causal diagnosis may not be initially obvious, but valuable clues can usually be found in the conventional chest radiograph to assist with appropriate early management. …”
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2292Review of Current Strategies for Delivering Alzheimer’s Disease Drugs across the Blood-Brain Barrierpor Wong, Ka Hong, Riaz, Muhammad Kashif, Xie, Yuning, Zhang, Xue, Liu, Qiang, Chen, Huoji, Bian, Zhaoxiang, Chen, Xiaoyu, Lu, Aiping, Yang, Zhijun“…Overall, we aim to provide ideas and clues to design effective drug delivery systems for penetrating the blood-brain barrier to treat Alzheimer’s disease.…”
Publicado 2019
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2293“…Although it is still not clear precisely when and where the outbreak began and symptom-based reports are unlikely to reveal the answer, indirect methods including phylogenetics provide important clues, and we consider whether intense influenza activity as far back as 1915 in the USA may have been caused by viral strains closely related to the 1918 one.…”
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2294“…Knowledge of the location of SVs within a neuron can thus provide valuable clues about the location of neurotransmitter release within a neuron and the downstream neurons to which a given neuron is connected, important information for understanding how neural circuits generate behavior. …”
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2295“…In this review, we aim to display more evidences and possible mechanisms accounting for the antagonism between these 2 pathways, which might provide some clues for further study in cancer.…”
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2296“…Despite this, we discuss the intriguing possibility that organisms on the path from the first eukaryotic common ancestor to the last common ancestor of all eukaryotes did not possess a nucleus at all—at least not in a form we would recognize today—and that the nucleus in fact arrived relatively late in the evolution of eukaryotes. The clues to this alternative evolutionary path lie, most of all, in recent discoveries concerning the structure of the nuclear pore complex. …”
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2297por Jiang, Mingzuo, Wu, Nan, Chen, Xi, Wang, Weijie, Chu, Yi, Liu, Hao, Li, Wenjiao, Chen, Di, Li, Xiaowei, Xu, Bing“…Diverse animal models have been proposed to replicate particular characteristics of NAFLD and NASH and have provided significant clues to the critical molecular targets of NASH treatment. …”
Publicado 2019
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2298“…The network pharmacology approach presented here provided important clues for understanding the mechanisms of PTFC treatment in the development of NAFLD.…”
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2299por Jibri, Zaid, Jamieson, Paul, Rakhra, Kawan S., Sampaio, Marcos L., Dervin, Geoffrey“…The clinical evaluation can provide useful clues for the presence of such entity; however, the diagnosis can often be challenging especially in the absence of a documented history of patellar dislocation. …”
Publicado 2019
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2300“…These results could provide clues for the development of highly specific G-quadruplex probes.…”
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