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  1. 2501
    por Welsh, James S.
    Publicado 2011
    “…These observations might hold invaluable clues to the immunobiology and possible immunotherapy of cancer.…”
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  2. 2502
    por Norscia, Ivan, Palagi, Elisabetta
    Publicado 2011
    “…Clinical, psychological, and neurobiological clues suggest a link between yawn contagion and empathy in humans (Homo sapiens). …”
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  3. 2503
    “…There is often a paucity of clues as to the underlying pathology, and while the diagnosis will usually prove to be either Alzheimer's disease or vascular dementia, there may be clinical features suggesting rarer alternatives. …”
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  4. 2504
    “…It is found that the solid model can determine ventricular dynamics which can well reflect the deformation distribution in the heart and imply early clues of cardiac diseases.…”
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  5. 2505
    “…To better understand and explain the findings from both types of studies and to provide clues to improve the power of an association study with only common SNPs genotyped, we study the correlation between common SNPs and the presence of rare alleles within a region in the genome and look at the capability of common SNPs in strong linkage disequilibrium with each other to capture single rare alleles. …”
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  6. 2506
    “…A balanced approach to screening that allows early recognition of SARS without unnecessary isolation of patients with other respiratory illnesses will require clinicians not only to look for suggestive clinical features but also to routinely seek epidemiologic clues suggestive of SARS coronavirus exposure. Key epidemiologic risk factors include 1) exposure to settings where SARS activity is suspected or documented, or 2) in the absence of such exposure, epidemiologic linkage to other persons with pneumonia (i.e., pneumonia clusters), or 3) exposure to healthcare settings. …”
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  7. 2507
    por Zatorre, Robert J., Baum, Shari R.
    Publicado 2012
    “…More broadly, this dissociation offers clues about the interface between sensory and motor systems, and highlights the idea that multiple processing streams are a ubiquitous feature of neuro-cognitive architectures.…”
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  8. 2508
    “…Although cutaneous manifestations in patients with cardiac myxoma are frequent, in rare cases, cutaneous signs have been clues to the correct diagnosis. We report a 42-year-old male who presented with recurrent multiple purpuric patches on both palms and soles for 4 months. …”
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  9. 2509
    “…Studying intercellular genome and epigenome variations has provided new clues to the delineation of molecular mechanisms that regulate development, function and plasticity of the human central nervous system (CNS). …”
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  10. 2510
    “…Although the etiology of PD is not completely understood and is believed to be multifactorial, oxidative stress and mitochondrial dysfunction are widely considered major consequences, which provide important clues to the disease mechanisms. Studies have explored the role of free radicals and oxidative stress that contributes to the cascade of events leading to dopamine cell degeneration in PD. …”
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  11. 2511
    “…Although an association between chemokines and vascular diseases has also been reported, the relationship between type I IFN and chemokines in vascular endothelial cells (VEC) remains unclear. To provide clues to pathogenesis of the diseases, we analysed the effects of type I IFN on chemokine production in human VEC. …”
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  12. 2512
    “…Processing of these large data sets is inherently multidimensional as length, abundance, sequence composition, and genomic location all hold clues to sRNA function. Analysis can be challenging because the formulation and testing of complex hypotheses requires combined use of visualization, annotation and abundance profiling. …”
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  13. 2513
    “…These all provided rich clues for revealing the transcriptional regulation mechanism of silkworm organ differentiation, growth and development, sexual dimorphism, and response to pathogen infection.…”
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  14. 2514
    “…This review will focus on some of the potential venoms and toxins along with nanoparticle conjugated venom-toxins of snakes, amphibians, scorpions and bees, etc., for possible therapeutic clues against emerging diseases.…”
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  15. 2515
    por Chinen, Katsuya, Fujioka, Yasunori
    Publicado 2012
    “…This case showed a unique pulmonary vascular pathology featuring plasma cell proliferation and it provides clues towards understanding the pathogenesis with this background.…”
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  16. 2516
    por Zong, Meijuan, Jia, Lei, Li, Liang
    Publicado 2013
    “…Intrahepatic cholangiocarcinomas (IHCCs) are morphologically and biologically similar to pancreatic ductal adenocarcinomas (PDACs), so newly identified PDAC-associated genes or proteins could provide clues for screening novel biomarkers for IHCC. In this study, the expression of three novel PDAC tumor markers (T-box transcription factor-4 [TBX4], heat shock protein-60 [HSP60], and Parkinson protein-7 [DJ-1]) identified in previous proteomic studies in IHCC tumors were immunohistochemically detected. …”
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  17. 2517
    “…In addition to providing an analog for RSL formation, CaCl(2) brines and chloride deposits in basins may provide clues to the origin of ancient chloride deposits on Mars dating from the transition period from “warm/wet” to “cold/dry” climates.…”
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  18. 2518
    “…Metabolic biomarkers reflecting these processes may not only provide clues for etiological understanding of colorectal carcinogenesis but also might be an alternative way to define an “obesity phenotype” that is relevant for colorectal cancer development.…”
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  19. 2519
    “…Compounds belonging to the green leaf volatiles class appeared to be important clues in host-plant selection by this oligophagous species.…”
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  20. 2520
    “…Here, we consider recent insights into how the redox response becomes deregulated under diabetic conditions, as well as the therapeutic benefits of antioxidants, which may provide clues for developing strategies aimed at the treatment or prevention of diabetes associated with β-cell failure.…”
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