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  1. 2701
    “…This review aims to summarize the currently validated insect AVPs, explore potential new insect AVPs and to discuss their possible mechanism of synthesis and action, with a view to providing clues to unravel the mechanisms of insect antiviral immunity and to develop insect AVP-derived antiviral drugs.…”
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    Antimicrobial Peptides as Potential Antiviral Factors in Insect Antiviral Immune Response
  2. 2702
    por Icenogle, Timothy
    Publicado 2020
    “…Review of the basic science of other viral induced autoimmune disorders may give clues as to why immunosuppressive and immunomodulating regimens now appear to have some efficacy in COVID-19. …”
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    COVID-19: Infection or Autoimmunity
  3. 2703
    “…Thus, the imaging approach to establish the differential diagnosis includes excluding an ovarian, uterine, or tubal origin by recognizing these separately and by rebutting imaging clues pointing to these origins. This pictorial essay reviews some of the imaging findings that may suggest such location and presents some of the possible differential diagnoses by means of illustrative confirmed cases.…”
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    Tumors of the broad ligament: what and when to suspect such rare location
  4. 2704
    “…Comparing and contrasting the PR-DUB in mammals and Drosophila reiterates the importance of H2AK119Ub through evolution, provides clues as to how the PR-DUB is dysregulated in disease, and may enable new treatment approaches in cancers where the PR-DUB is disrupted.…”
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    Molecular Regulation of the Polycomb Repressive-Deubiquitinase
  5. 2705
    “…Quantum mechanical (QM) and hybrid quantum mechanical/molecular mechanical (QM/MM) molecular dynamics simulations of a recently reported dinuclear mercury(II)-mediated base pair were performed aiming to analyse its intramolecular bonding pattern, its stability, and to obtain clues on the mechanism of the incorporation of mercury(II) into the DNA. …”
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    Dynamic Structure and Stability of DNA Duplexes Bearing a Dinuclear Hg(II)-Mediated Base Pair
  6. 2706
    “…Previous work focused on inorganic proxies in this core revealed important clues of climatic conditions during the Heinrich Stadial 1 (HS1). …”
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    Molecular distribution and isotopic composition (δD and δ(13)C) of lipids dataset for a sediment core (GeoB16202-2) from the north-eastern Brazilian margin
  7. 2707
    “…It is believed that the populations in Korea hold important clues to how the species has been distributed south along the Eurasian continent to the Korean Peninsula. …”
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    The complete mitochondrial genome information of Phoxinus phoxinus (Cypriniformes: Cyprinidae) on the Korean Peninsula and the phylogenetic implication
  8. 2708
    por Lin, Lan, Xu, Jianping
    Publicado 2020
    “…In addition, the mechanistic elucidation of the interaction of fungal pigments with the host immune system provides valuable clues for fighting fungal infections. The great potential of fungal pigments have opened the avenues for academia and industries ranging from fundamental biology to pharmaceutical development, shedding light on our endeavors for disease prevention and treatment.…”
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    Fungal Pigments and Their Roles Associated with Human Health
  9. 2709
    “…Other currently available anticoagulants (ie, vitamin K antagonists and heparins) provide important clues for this. If such a target spot exists, tailored DOAC therapy may further benefit patients. …”
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    The relationship between DOAC levels and clinical outcomes: The measures tell the tale
  10. 2710
    “…Firstly, we design a Pose-based Triple Stream Network (PTSN) based on Long Short-Term Memory (LSTM) networks, capable of modeling long-term temporal pose dynamics of athletes, including pose-based appearance, motion and athletes’ interaction clues. Secondly, we propose a multi-state online matching algorithm based on bipartite graph matching and similarity scores produced by PTSN. …”
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    Online Multiple Athlete Tracking with Pose-Based Long-Term Temporal Dependencies
  11. 2711
    por Tan, Shiyi, Chen, Shi
    Publicado 2021
    “…In conclusion, the deeper molecular mechanism of these autophagy targets should be explored in order to provide feasible clues for silicosis therapy in the clinical setting.…”
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    Macrophage Autophagy and Silicosis: Current Perspective and Latest Insights
  12. 2712
    “…Due to the variability of presentation of intrauterine HSV infection, pathological examination of the placenta in the first 2–5 days of life in premature infants can provide clues to the diagnosis of neonatal HSV which may significantly impact the outcome.…”
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    Diagnosis of Neonatal Herpes Simplex Infection from the Placenta
  13. 2713
    “…The chronic neglected pruritus and elevated tryptase levels along with histological findings were the main clues that have led us to the final diagnosis of indolent systemic mastocytosis. …”
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    A rare manifestation of indolent systemic mastocytosis and its management during the coronavirus disease 2019 pandemic; educational lessons from Syria
  14. 2714
    “…Our study suggests an oncogenic potential of NR_026689 in ovarian cancer and might provide novel clues for the diagnosis and treatment of ovarian cancer in the clinic.…”
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    Knockdown of Long Noncoding RNA NR_026689 Inhibits Proliferation and Invasion and Increases Apoptosis in Ovarian Carcinoma HO-8910PM Cells
  15. 2715
    por Holt, Jonathon N
    Publicado 2021
    “…Prognosis is heavily reliant on disease stage, thus diagnostic clues suggesting the possibility of underlying malignancy in the presentation of stroke should prompt a thorough investigation to exclude malignancy.…”
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    A case of multifocal stroke—the first presentation of underlying ovarian malignancy
  16. 2716
    “…Recent findings suggest that TBI might facilitate Alzheimer’s pathogenesis by altering metabolism, which provides clues to metabolic link between TBI and AD. In this review, we will explore how TBI-induced metabolic changes contribute to the development of AD.…”
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    Glucose metabolism: A link between traumatic brain injury and Alzheimer’s disease
  17. 2717
    “…In recent years, multiple epigenetic barriers are reported, which gives us clues to improve reprogramming efficiency. Here, we reviewed the reprogramming process and reprogramming defects of several important epigenetic marks and highlighted epigenetic barriers that may lead to the aberrant reprogramming. …”
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    Advance in the Role of Epigenetic Reprogramming in Somatic Cell Nuclear Transfer-Mediated Embryonic Development
  18. 2718
    por Shimonishi, Kei, Kawashima, Hiroaki
    Publicado 2020
    “…While eye gaze data contain promising clues for inferring the interests of viewers of digital catalog content, viewers often dynamically switch their focus of attention. …”
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    A Two-step Approach for Interest Estimation from Gaze Behavior in Digital Catalog Browsing
  19. 2719
    “…Neurological symptoms can provide clues to potential tumors, and early antitumor treatment may have contributed to the positive prognosis of PCD secondary to NEC in the present case.…”
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    Acute-onset paraneoplastic cerebellar degeneration secondary to neuroendocrine carcinoma with atypical prognosis: a case report
  20. 2720
    “…Pangenome analyses reveal major clues on evolutionary instances and critical genome core conservation. …”
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    Pangenomics of the Symbiotic Rhizobiales. Core and Accessory Functions Across a Group Endowed with High Levels of Genomic Plasticity
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