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  1. 2721
    “…Mechanisms underlying sex determination and differentiation in animals are known to encompass a diverse array of molecular clues. Recent innovations in high-throughput sequencing and mass spectrometry technologies have been widely applied in non-model organisms without reference genomes. …”
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    Sex Determination and Differentiation in Decapod and Cladoceran Crustaceans: An Overview of Endocrine Regulation
  2. 2722
    “…The morphologic and immunohistochemical clues leading to the correct diagnosis of PRA of the small bowel and the differential diagnostic problems are discussed; a comprehensive review of the literature has also been performed with a focus on survival.…”
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    Primary post-radiation angiosarcoma of the small bowel. Report of a case and review of the literature
  3. 2723
    por Tsuchiya, Hiroyuki, Shiota, Goshi
    Publicado 2021
    “…These profound mechanisms provide important clues for the development of novel tumor immunotherapies.…”
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    Immune evasion by cancer stem cells
  4. 2724
    “…This review infers the insight into the interaction of PTX3 in RA and aims to provide novel clues for potential therapeutic target of RA in clinic.…”
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    Perspectives on long pentraxin 3 and rheumatoid arthritis: several potential breakthrough points relying on study foundation of the past
  5. 2725
    “…To this end, the study of HIV highly exposed seronegative (HESN) female commercial sex workers (CSWs), who constitute a model of natural immunity to HIV, provides an exceptional opportunity to determine important clues for the development of preventive strategies. …”
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    The Importance of Regulation in Natural Immunity to HIV
  6. 2726
    “…Therefore, systematically identifying dysregulation events is an effective path for understanding carcinogenesis and provides insightful clues to build predictive signatures with mechanistic interpretability for cancer precision medicine. …”
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    DysRegSig: an R package for identifying gene dysregulations and building mechanistic signatures in cancer
  7. 2727
    por Liu, Hai, Xue, Shaowu
    Publicado 2021
    “…Based on evidence and clues from existing research, we propose some issues that need to be addressed in the future.…”
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    Interplay between hydrogen sulfide and other signaling molecules in the regulation of guard cell signaling and abiotic/biotic stress response
  8. 2728
    “…We herein present a rare case of DFSP of the breast parenchyma in a 41-year-old female with emphasis on the diagnostic clues and the differential diagnosis with other benign and malignant spindle cell lesions of the breast.…”
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    Dermatofibrosarcoma protuberans: a tumor in the wide spectrum of the bland-looking spindle cell lesions of the breast
  9. 2729
    por Neale, Holly, Hawryluk, Elena B.
    Publicado 2021
    “…Whereas some dermatologic signs in children overlap with those in adults, other skin findings are reported with higher frequency in children and may be clues to multisystemic sequelae. This article describes presentation, pathophysiologic theories, and management strategies for cutaneous manifestations of COVID-19 in children.…”
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    COVID-19 Pediatric Dermatology
  10. 2730
    “…The results indicate that dexamethasone can reduce mortality in vvIBDV-infected chickens and may provide therapeutic clues for saving individual birds infected by the virus.…”
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    Dexamethasone reduces infectious bursal disease mortality in chickens
  11. 2731
    “…We intend this article to be an instrument, not only to identify what was done in 2020, but to point out clues for the future.…”
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    EU27 Higher Education Institutions and COVID-19, Year 2020
  12. 2732
    por Han, Yihan, Wang, Tao
    Publicado 2021
    “…In order to improve the performance, we first convert the input labeled clues to the global prior probability, and propagate the’soft’ prior probability to learn the posterior probability instead of directly propagating the’hard’ labeled data. …”
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    Semi-Supervised Clustering for Financial Risk Analysis
  13. 2733
    “…Since the chained fragments provide reliable clues to find the global path, false matches on featureless structures or partial failures during the alignment could be recovered and perform accurate robot localization in changing environments. …”
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    Condition-Invariant Robot Localization Using Global Sequence Alignment of Deep Features
  14. 2734
    “…Totally, the prognostic assessment model indicated a promising predictive value, also providing clues for the interaction between ferroptosis and BCa immunity.…”
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    Development of a Ferroptosis-Related lncRNA Signature to Predict the Prognosis and Immune Landscape of Bladder Cancer
  15. 2735
    “…Evolution and extrathoracic imaging findings are important clues toward the diagnosis.…”
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    Tumor and tumorlike conditions of the pleura and juxtapleural region: review of imaging findings
  16. 2736
    “…Many recent studies suggest that neuroimaging and few clinical features can provide clues to the underlying etiology. However, serological tests can provide a confirmatory evidence. …”
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    Working up a child with demyelinating optic neuritis: Striking a balance!
  17. 2737
    “…Additionally, the isolation and analyses of mutants with defects in phototactic-sign regulation may provide clues for their application to the efficient cultivation of algae.…”
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    Characterization of Chlamydomonas reinhardtii Mutants That Exhibit Strong Positive Phototaxis
  18. 2738
    “…In this review, we summarize all epidemiological and clinical clues that suggest the existence of breastfeeding as a neglected route for MTCT of arboviruses and we decipher some of the mechanisms that chronologically occur during MTCT via breastfeeding by focusing on ZIKV transmission process.…”
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    Mother-to-Child Transmission of Arboviruses during Breastfeeding: From Epidemiology to Cellular Mechanisms
  19. 2739
    “…This study opens important clues to the development of more in-depth and comparative approaches, necessary for the continuous improvement of the healthcare provided in the context of surgical practice.…”
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    Motivations Influencing the Surgeon’s Healthcare Unit Choice to Perform Surgery: A Confirmatory Study in Portugal
  20. 2740
    por Li, Xiao, Qian, Keqing, Han, Weiwei
    Publicado 2021
    “…We reveal a new inhibitor for SI and provide reasonable theoretical clues for inhibitor binding to SI.…”
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    Prediction of hyaluronic acid target on sucrase-isomaltase (SI) with reverse docking and molecular dynamics simulations for inhibitors binding to SI
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