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  1. 2901
    “…Tumor specificity was chosen as the core of tumor antigen evaluation, together with other relevant clues. Various platforms of gene expression, including microarray, expressed sequence tag and SAGE data, were processed and integrated by several penalty algorithms. …”
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    HPtaa database-potential target genes for clinical diagnosis and immunotherapy of human carcinoma
  2. 2902
    por Soukup, Garrett A.
    Publicado 2006
    “…However, the high degree of nucleotide conservation offers few clues regarding the higher-order structural organization of the catalytic core. …”
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    Core requirements for glmS ribozyme self-cleavage reveal a putative pseudoknot structure
  3. 2903
    “…The importance of medicinal plants in traditional healthcare practices, providing clues to new areas of research and in biodiversity conservation is now well recognized. …”
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    Traditional use of medicinal plants among the tribal communities of Chhota Bhangal, Western Himalaya
  4. 2904
    por Harris, C C
    Publicado 1996
    “…Genetic analysis of human cancer is providing clues to the etiology of these diverse tumors and to the functions of the p53 gene. …”
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    p53 tumor suppressor gene: at the crossroads of molecular carcinogenesis, molecular epidemiology, and cancer risk assessment.
  5. 2905
    “…A determination of the targets of these autoimmune reactions may provide valuable clues to help understand the immunopathogenesis of this disease.…”
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    Clonal expansion is a characteristic feature of the B-cell repertoire of patients with rheumatoid arthritis
  6. 2906
    “…CONCLUSIONS: Given these results, different methods of multivariate data reduction may provide unique clues on the clustering of this complex syndrome.…”
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    Phenotypic, genetic, and genome-wide structure in the metabolic syndrome
  7. 2907
    “…The analysis revealed hundreds of missed gene calls, new split genes and indels, several of which are species specific and hence provide valuable clues to the understanding of the genome basis of Brucella pathogenicity and host specificity.…”
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    A versatile computational pipeline for bacterial genome annotation improvement and comparative analysis, with Brucella as a use case
  8. 2908
    “…How Rho–ROCK–MLC2 activation occurs at these distinct cellular locations is not known, but the emerging concept that endocytic dynamics can coordinate key intracellular signaling events provides vital clues. We report that endosomes containing the promigratory receptor Endo180 (CD280) can generate Rho–ROCK–MLC2–based contractile signals. …”
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    Endosomes generate localized Rho–ROCK–MLC2–based contractile signals via Endo180 to promote adhesion disassembly
  9. 2909
    “…Skeletal and cardiac muscles have different isoforms of the two proteins and present two structurally and functionally distinct modes of interaction. We use structural clues to trace the evolution of the dichotomy from a single, generic type of e–c coupling to a diversified system involving a novel mechanism for skeletal muscle activation. …”
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    Evolution of skeletal type e–c coupling: a novel means of controlling calcium delivery
  10. 2910
    “…These observations indicate that Lnk plays critical roles in the expansion and function of early hematopoietic progenitors, and provide useful clues for the amplification of hematopoietic progenitor cells.…”
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    Enhanced Hematopoiesis by Hematopoietic Progenitor Cells Lacking Intracellular Adaptor Protein, Lnk
  11. 2911
    “…This may provide useful clues into the etiology, prevention and management of childhood autism as well as oculocutaneous albinism.…”
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    Childhood autism in a 13 year old boy with oculocutaneous albinism: a case report
  12. 2912
    “…Proteins which have multiple localizations will provide more clues. This kind of proteins may take a high proportion, even more than 35%. …”
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    DBMLoc: a Database of proteins with multiple subcellular localizations
  13. 2913
    “…The study of clusters of PBC may provide clues as to possible triggers in the induction of immunopathology. …”
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    Geographic Clusters of Primary Biliary Cirrhosis
  14. 2914
    “…CONCLUSIONS/SIGNIFICANCE: We predict that studies providing clues to the evolutionary and ecological processes underlying microbial distributions will reconcile the ongoing debate between the Baas Becking vs. …”
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    Contrasting Microbial Community Assembly Hypotheses: A Reconciling Tale from the Río Tinto
  15. 2915
    por Ng, Kim-Choy, Lai, Shih-Wei
    Publicado 2002
    “…BACKGROUND: In order to determine reliable clues for early diagnosis of acute appendicitis, this study was conducted to examine the related factors in patients with clinically suspected acute appendicitis. …”
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    Clinical analysis of the related factors in acute appendicitis.
  16. 2916
    “…Identifying interaction sites in proteins provides important clues to the function of a protein and is becoming increasingly relevant in topics such as systems biology and drug discovery. …”
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    Prediction of Protein–Protein Interaction Sites in Sequences and 3D Structures by Random Forests
  17. 2917
    “…Written text is one of the fundamental manifestations of human language, and the study of its universal regularities can give clues about how our brains process information and how we, as a society, organize and share it. …”
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    Modeling Statistical Properties of Written Text
  18. 2918
    “…Limited studies on IRS expression in human tumors and studies on IRS function in human tumor cell lines and in mouse models have provided clues to the potential function of these adaptor proteins in human cancer. …”
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    Expression and function of the insulin receptor substrate proteins in cancer
  19. 2919
    “…With the new insight into biology offered by genome sequences, the elucidation of the gene content encoding proteins provides clues toward understanding the microbial lifestyle related to habitat and niche. …”
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    Genome dynamics in major bacterial pathogens
  20. 2920
    “…INTRODUCTION: Important clues in the recognition of individuals with dystrophin gene mutations are illuminated in this case report. …”
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    Dystrophinopathy presenting with arrhythmia in an asymptomatic 34-year-old man: a case report
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