“…When the headache occurs as the only manifestation of an acute coronary event, the clues for suspicion are a) older age at onset, b) no past medical history of headache, c) presence of risk factors for vascular disorders and d) onset of headache under stress. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Unraveling the molecular clues of liver proliferation has become conceivable thanks to the model of two-third hepatectomy. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This article will discuss the relevant clues of post-translational modifications, phosphorylated proteins, and useful proteomics approaches to identify molecular cancer signatures. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, the analysis reveals further clues regarding potential radiation events that occurred immediately preceding the Black Death, and the legacy it may have left in modern Y. pestis populations. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Among the various sites of disease manifestations, skin and mucosae represent a neglected organ where the dermatologist can easily spot diagnostic clues, which consistently integrate joint hypermobility and other orthopedic/neurologic manifestations at physical examination. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The striking facial phenotype in addition to other features such as severely impaired speech, hypotonia, microcephaly, short stature, seizures, corpus callosum agenesis, congenital heart defects, hypospadias, and Hirschsprung disease are particularly important clues for the initial clinical diagnosis. All molecularly confirmed cases with typical MWS have a heterozygous loss-of-function mutation in the zinc finger E-box protein 2 (ZEB2) gene, also called SIP1 (Smad-interacting protein 1) and ZFHX1B, suggesting that haploinsufficiency is the main pathological mechanism. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These data demonstrate that differentially methylated genes are significantly overrepresented in NYGGF4-overexpression adipocytes, providing valuable clues for further exploration of the role of NYGGF4 in insulin sensitivity regulation.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The atypical clinical features in our case can reconsider the diagnostic clues of renal epidermoid cysts that have been reported before, and the unique immunohistochemical results may understand the histogenetic implications of the lesion.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The information from this study might provide some important clues to uncover the key proteins involved in the formation of cholesterol gallstone.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our computational results rationalize the oncogenic nature of the Y220C mutation, explain the binding of a drug-like molecule already designed to restore the function of p53 and provide clues to help improve this function-rescue strategy and to apply in other drug design or re-engineering techniques.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Keeping in mind how important spectators are for team sports, understanding factors that affect game attendance will offer essential clues in terms of increasing spectator attendance. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Due to the rare occurrence of these lesions, we will focus on the main clues in the diagnosis and management of such lesions, which are challenging. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Although structural studies offer some clues as to what unlocking might entail, the molecular basis of this conformational change remains an open question. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Third, the rules are specified graphically in an interface that provides visual clues for potential modifications. Together, the presented methods offer a high degree of freedom in the specification and exploration of rule-based mappings and avoid the limitations of a linguistic rule formulation.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The diagnostic processes include close analyses of a child’s body in order to identify ‘clues’ to possible genetic variation. When the genetic variation identified is new and complex there is significant uncertainty about what relationship that variation has to childhood development and what it will mean for a child’s future. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This image-rich review discusses the imaging evaluation of patients with suspected intracranial involvement and malignancy, describes typical imaging findings of parenchymal brain metastasis on CT and MRI, and provides clues to specific histological diagnoses such as the presence of hemorrhage. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results provide novel clues for the understanding of the genetic mechanisms regulating FA brain expression and improve the current knowledge of the FADS moderation effect on cognition.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As a uniquely vertebrate cell population, it also offers important clues regarding vertebrate origins. In the past 30 yr, introduction of recombinant DNA technology has facilitated the dissection of the genetic program controlling neural crest development and has provided important insights into gene regulatory mechanisms underlying cell migration and differentiation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In addition, genome/cDNA sequences make it possible to predict proteins for which there is no experimental evidence. Clues for function of hypothetical proteins are provided by sequence similarity with proteins of known function in model organisms. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…WM presents fascinating clues on neoplastic B-cell development, including the recent discovery of a specific gain-of-function mutation in the MYD88 adapter protein. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso