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  1. 3121
    “…The discovery of the novel peptide may provide useful clues for new drug discoveries.…”
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    PSN-PC: A Novel Antimicrobial and Anti-Biofilm Peptide from the Skin Secretion of Phyllomedusa-camba with Cytotoxicity on Human Lung Cancer Cell
  2. 3122
    “…Thus, the accurate identification of conotoxin types will provide key clues for the biological research and clinical medicine. …”
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    Recent Advances in Conotoxin Classification by Using Machine Learning Methods
  3. 3123
    por Xu, Jie-Hua, Tang, Feng-Ru
    Publicado 2018
    “…We hope this review can provide some clues for better understanding the mechanism of epileptogenesis, and for the development of new anti-epileptic drugs targeting on VDCCs and CBPs.…”
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    Voltage-Dependent Calcium Channels, Calcium Binding Proteins, and Their Interaction in the Pathological Process of Epilepsy
  4. 3124
    “…We discuss the genetic convergence and disruptions in biochemical mechanisms which may point to clues surrounding pathogenesis-targeted treatment and other promising therapeutic strategies in the future.…”
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    Parkinsonism in Inherited Metabolic Disorders: Key Considerations and Major Features
  5. 3125
    “…This review introduces the structural characteristics and molecular mechanisms of action of these two anti-VEGF drugs, and summarizes the clinical trials evaluating their efficacy and safety, with the hope to provide clues for designing optimal and personalized therapeutic regimens for DME patients.…”
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    The efficacy and safety of aflibercept and conbercept in diabetic macular edema
  6. 3126
    “…Conversely, non-diabetic mouse models that represent the hallmark vascular disorders in DR, such as pericyte deficiency and retinal ischemia, have provided clues toward an understanding of the sequential events that are responsible for vision-impairing conditions. …”
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    Pathophysiology of Diabetic Retinopathy: The Old and the New
  7. 3127
    “…We expect that the nanoscale like-charge attraction mechanism provides new clues for viral entry and general rules for rational design of anionic carriers for therapeutics.…”
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    DNA Nanostructure-Programmed Like-Charge Attraction at the Cell-Membrane Interface
  8. 3128
    “…Most promisingly, individual genomic loci offer entirely novel clues about PTSD etiology, providing the raw material for transformative discoveries, and the future of PTSD research is bright.…”
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    Robust Findings From 25 Years of PTSD Genetics Research
  9. 3129
    “…Structural studies with PrP variants promise new clues regarding the proposed conversion mechanism and may help identify “hot spots” in PrP(C) involved in the pathogenic conversion. …”
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    Probing Early Misfolding Events in Prion Protein Mutants by NMR Spectroscopy
  10. 3130
    “…A preliminary structure-activity relationship (SAR) study was also performed, which offered valuable clues for the design of further new EβF analogues.…”
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    Novel (E)-β-Farnesene Analogues Containing 2-Nitroiminohexahydro-1,3,5-triazine: Synthesis and Biological Activity Evaluation
  11. 3131
    “…This study provides new clues for the development of attenuated trichothecene toxins in future treatment of liver cancer.…”
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    Two Trichothecene Mycotoxins from Myrothecium roridum Induce Apoptosis of HepG-2 Cells via Caspase Activation and Disruption of Mitochondrial Membrane Potential
  12. 3132
    por Duann, Pu, Lin, Pei-Hui, Lianos, Elias A.
    Publicado 2018
    “…The data identify MPs most and least capable of inducing DAF and reducing Nephrin expression and provide clues into expected outcomes of animal studies assessing MP efficacy in upregulating the cytoprotective proteins HO-1 and DAF.…”
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    Data on characterization of metalloporphyrin-mediated HO-1 and DAF induction in rat glomeruli and podocytes
  13. 3133
    “…These findings provide valuable clues for investigating the effects of aging on fracture healing but should be validated through further experiments.…”
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    Bioinformatics Analysis of the Molecular Mechanism of Aging on Fracture Healing
  14. 3134
    “…This study reveals the inner 3D structure of the secondary particles while opening up questions on the unexpected crystalline structural distributions, which could offer clues for future studies on this promising cathode material for lithium-ion batteries.…”
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    Correlated X-Ray 3D Ptychography and Diffraction Microscopy Visualize Links between Morphology and Crystal Structure of Lithium-Rich Cathode Materials
  15. 3135
    “…Preclinical animal models have been developed for a variety of human ophthalmological diseases to mirror disease mechanisms, location of the affected region in the eye and severity. These models offer clues to aid in our fundamental understanding of disease pathogenesis and enable progression of new therapies to clinical development by providing an opportunity to gain proof of concept (POC). …”
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    Translational Preclinical Pharmacologic Disease Models for Ophthalmic Drug Development
  16. 3136
    “…INTRODUCTION: Digital radiography lacks visual clues of exposure techniques used to obtain radiographs, therefore manufacturers have included exposure indicators (EIs). …”
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    Retrospective evaluation of exposure indicators: a pilot study of exposure technique in digital radiography
  17. 3137
    “…While the origin of molecular homochirality still remains mysterious, the fabrication of homochiral assemblies from achiral molecules has attracted considerable interest since it provides many clues to understand the origin of molecular chirality. …”
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    Towards homochiral supramolecular entities from achiral molecules by vortex mixing-accompanied self-assembly
  18. 3138
    por Colom, Roberto, Román, Francisco J.
    Publicado 2018
    “…The integration of these multimodal brain results provides clues about those observed in behavior. Our findings, along with previous research and current technological advances, are considered from the perspective that we now live in ideal times for (a) moving from the group to the individual and (b) developing personalized training programs.…”
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    Enhancing Intelligence: From the Group to the Individual
  19. 3139
    “…He presented with a firm asymptomatic nodule in his left upper lip of 2-year duration. The initial clue to the diagnosis was made on fine needle aspiration cytology (FNAC), and a final diagnosis was based on histopathological examination. …”
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    Fine needle aspiration cytology as a preliminary diagnostic tool in chondroid syringoma: a case report and review
  20. 3140
    “…These results help us to understand the regulation of cereulide production and provide clues for developing control measurements.…”
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    CesH Represses Cereulide Synthesis as an Alpha/Beta Fold Hydrolase in Bacillus cereus
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