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  1. 3461
    por Kaouther, Mnasria, Ridha, Oueslati
    Publicado 2011
    “…This study therefore provide new molecular clues regarding the split between these two phenomena and unravel new mechanisms of action of anti-CD25 monoclonal antibodies that may contribute to their action in several human immunological disorders such as autoimmune diseases and acute allograft rejection.…”
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    Dendritic Cell-Based Graft Tolerance
  2. 3462
    “…Module formation, scoring by evolutionary criteria and visual clues reduce the amount of predictions to a manageable scale. …”
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    Visualization and Exploration of Conserved Regulatory Modules Using ReXSpecies 2
  3. 3463
    por Paramasivam, Nagarajan, Linke, Dirk
    Publicado 2011
    “…The subcellular localization (SCL) of proteins provides important clues to their function in a cell. In our efforts to predict useful vaccine targets against Gram-negative bacteria, we noticed that misannotated start codons frequently lead to wrongly assigned SCLs. …”
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    ClubSub-P: Cluster-Based Subcellular Localization Prediction for Gram-Negative Bacteria and Archaea
  4. 3464
    “…The quantity and location of secretions in breast cancer offer clues to differentiating these.…”
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    A cytomorphological study of secretions in breast cancer
  5. 3465
    “…Hence, metabolism may hold the clues to the survival of organisms subjected to nitrosative stress and may provide therapeutic cues against RNS-resistant microbes.…”
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    The Metabolic Reprogramming Evoked by Nitrosative Stress Triggers the Anaerobic Utilization of Citrate in Pseudomonas fluorescens
  6. 3466
    “…The detailed feature analysis in this paper might provide important clues for understanding the mechanism of the PCA formation and guide relevant experimental validations.…”
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    Prediction of Protein Modification Sites of Pyrrolidone Carboxylic Acid Using mRMR Feature Selection and Analysis
  7. 3467
    por Spritz, Richard A.
    Publicado 2011
    “…These genes and pathways provide insights into underlying pathogenetic mechanisms and potential triggers of GV, establish relationships to other autoimmune diseases, and may provide clues to potential new approaches to GV treatment and perhaps even prevention. …”
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    Six decades of vitiligo genetics: Genomewide studies provide insights into autoimmune pathogenesis
  8. 3468
    “…The aim of the present study was to explore the relationship between SDH and depression, and to provide new evidences and clues for depression control and prevention. METHODOLOGY/PRINCIPAL FINDINGS: This research was a cross-sectional survey executed door to door from October 2006 to April 2008, with a sample of 3,738 individuals aged 18 and older in rural China. …”
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    Social Determinants of Health and Depression: A Preliminary Investigation from Rural China
  9. 3469
    “…This work extends fullerene research into numerous topologically possible, heptagon-incorporating isomers and provides clues to an understanding of the heptagon-involved growth mechanism and heptagon-dependent properties of fullerenes.…”
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    Carbon arc production of heptagon-containing fullerene[68]
  10. 3470
    “…Our study therefore provides important clues about the chicken-or-egg dilemma associated with the central dogma of molecular biology by showing that ribosomal history is driven by the gradual structural accretion of protein and RNA structures. …”
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    Ribosomal History Reveals Origins of Modern Protein Synthesis
  11. 3471
    “…Further analysis of the ss-motif information contents revealed strongly significant deviations from those of the respective training sets, revealing important potential clues as to how the sequence and structural information of RNA hairpins are utilized by the miRNA processing apparatus. …”
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    Integrated Sequence-Structure Motifs Suffice to Identify microRNA Precursors
  12. 3472
    “…The results from the study may provide vital clues in establishing affect of polymorphism on phenotype and in elucidating drug response.…”
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    Cataloguing functionally relevant polymorphisms in gene DNA ligase I: a computational approach
  13. 3473
    por Qingliang, X, Jianxin, W
    Publicado 2010
    “…OBJECTIVE: The aim of this study is to try to find out some useful clues for the diagnosis of EBTB, especially the early diagnosis. …”
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    Investigation of endobronchial tuberculosis diagnoses in 22 cases
  14. 3474
    por Miranda, Rajesh C.
    Publicado 2012
    “…An assessment of the regulation and function of these miRNAs provides important clues about the mechanisms that underlie fetal vulnerability to alterations in the maternal-fetal environment and yields insights into the genesis of FASD.…”
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    MicroRNAs and Fetal Brain Development: Implications for Ethanol Teratology during the Second Trimester Period of Neurogenesis
  15. 3475
    “…Therefore, computational methods are needed to present clues to the biomedical community to explore genes that are more likely to be related to a specific disease as biomarker. …”
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    Biomarker Identification for Prostate Cancer and Lymph Node Metastasis from Microarray Data and Protein Interaction Network Using Gene Prioritization Method
  16. 3476
    por Tegeder, Mechthild, Ward, John M.
    Publicado 2012
    “…To date, AAPs and LHTs have mainly been characterized in Arabidopsis (eudicots) and these studies provide clues to the functions of the newly identified homologs.…”
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    Molecular Evolution of Plant AAP and LHT Amino Acid Transporters
  17. 3477
    “…These observations demonstrate that there are distinct differences in the radiation responses of normal endothelial cells obtained from diverse organs, which may provide important clues for protection of normal tissue from radiation exposure.…”
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    Radio-sensitivities and angiogenic signaling pathways of irradiated normal endothelial cells derived from diverse human organs
  18. 3478
    “…CONCLUSIONS: The drug cocktail network constructed in this work provides useful insights into the underlying rules of effective drug combinations and offer important clues to accelerate the future discovery of new drug combinations.…”
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    The drug cocktail network
  19. 3479
    “…Studying the seasonality of conceptions of children later diagnosed with autism may yield clues to potential etiological drivers. OBJECTIVE: To assess if the conceptions of children later diagnosed with autism cluster temporally in a systematic manner and whether any pattern of temporal clustering persists over time. …”
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    The Disappearing Seasonality of Autism Conceptions in California
  20. 3480
    “…In insects, the first extraction of motion and direction clues from local brightness modulations is thought to take place in the medulla. …”
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    Neuronal representation of visual motion and orientation in the fly medulla
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