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  1. 3541
    “…The findings in this study are new clues specific to this study and give us a direction for targeted cancer therapy, and it should be validated in vivo or in vitro in the future.…”
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    Evolution of Network Biomarkers from Early to Late Stage Bladder Cancer Samples
  2. 3542
    “…The lesion was considered metastatic from lung cancer on the basis of clinical and histological clues. The exact mechanism of lung cancer metastasis to the nasopharynx in this case remains unclear because either implantation or hematogenous and lymphatic spread is possible. …”
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    Lung squamous cell carcinoma metastasizing to the nasopharynx following bronchoscopy intervention therapies: a case report
  3. 3543
    “…These observations provide clues for confirmatory and cause-effect prospective investigations. …”
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    Blastopathies and microcephaly in a Chornobyl impacted region of Ukraine
  4. 3544
    “…The implications drawn from the 21 studies put some clues for future practice in this area including the need to conduct more rigorously designed randomized controlled trials.…”
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    Current Evidence on Auricular Therapy for Chemotherapy-Induced Nausea and Vomiting in Cancer Patients: A Systematic Review of Randomized Controlled Trials
  5. 3545
    “…The findings from this study could facilitate further characterization and utilization of these two novel antibiotics, and also provide useful clues for understanding the regulatory mechanisms that govern D. zeae virulence.…”
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    Production of Novel Antibiotics Zeamines through Optimizing Dickeya zeae Fermentation Conditions
  6. 3546
    “…Our results provide new systems-biology clues for the study of retinal ischemia.…”
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    Identification of Protein Network Alterations upon Retinal Ischemia-Reperfusion Injury by Quantitative Proteomics Using a Rattus norvegicus Model
  7. 3547
    “…Such knowledge provides us with clues for the identification of tick-associated pathogens and suggests ideas for the control of tick-borne diseases in China. …”
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    Tick-borne pathogens and the vector potential of ticks in China
  8. 3548
    por Berwick, Daniel C., Harvey, Kirsten
    Publicado 2014
    “…These observations provide clues to the normal function of these proteins in healthy neurones and suggest that deregulated Wnt signaling might be a frequent pathomechanism leading to PD. …”
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    The regulation and deregulation of Wnt signaling by PARK genes in health and disease
  9. 3549
    “…Results from the present study suggested that members of the ONAC genes with overlapping expression pattern may have pleiotropic biological functions in regulation of defense response against different abiotic and biotic stresses, which provide clues for further functional analysis of the ONAC genes in stress tolerance and pathogen resistance.…”
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    Comprehensive Analysis Suggests Overlapping Expression of Rice ONAC Transcription Factors in Abiotic and Biotic Stress Responses
  10. 3550
    “…Nature provides amazing clues to develop unconventional components that are capable of compliant interactions with the environment and living beings, avoiding mechanical and algorithmic complexity of robotic design. …”
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    Revealing bending and force in a soft body through a plant root inspired approach
  11. 3551
    “…We discuss not only RNase L-dependent (canonical) and -independent (noncanonical) pathways but also the possibility of the OAS family members as biomarkers for various diseases and clues to non-immunological functions based on recent studies. …”
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    Oligoadenylate synthase-like (OASL) proteins: dual functions and associations with diseases
  12. 3552
    por Gillberg, Linn, Ling, Charlotte
    Publicado 2015
    “…Accordingly, the novel clues to DNA methylation fingerprints in blood and tissues with deteriorated metabolic capacity indicate that blood-borne epigenetic biomarkers of T2D progression might become a reality. …”
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    The Potential Use of DNA Methylation Biomarkers to Identify Risk and Progression of Type 2 Diabetes
  13. 3553
    “…This study provides us with very important clues for revealing the importance of the UL49 locus alternative splicing.…”
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    Identification of the Alternative Splicing of the UL49 Locus of Human Cytomegalovirus
  14. 3554
    “…In addition, analysis of the asymmetric transcripts yielded clues regarding the post-transcriptional mechanisms that control cellular mRNA abundance during asymmetric cell divisions, which are common in developing organisms.…”
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    Asymmetric Transcript Discovery by RNA-seq in C. elegans Blastomeres Identifies neg-1, a Gene Important for Anterior Morphogenesis
  15. 3555
    “…In this review we discuss thrombosis in vasculitides, especially in Behçet’s syndrome, ANCA-associated vasculitis and large-vessel vasculitis, and provide pathogenetic and clinical clues for the different specialists involved in the care of these patients.…”
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    Thrombosis in vasculitis: from pathogenesis to treatment
  16. 3556
    “…Here, we discuss the interface between PID and AID, focusing on autoimmune manifestations early in life, which can be diagnostic clues for underlying PIDs. Inflammatory bowel disease in infants and children has been associated with IL-10 and IL-10R deficiencies, chronic granulomatous disease, immunedysregulation-polyendocrinopathy-enteropathy-X-linked syndrome (IPEX), autoinflammatory disorders, and others. …”
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    Early-Onset Autoimmune Disease as a Manifestation of Primary Immunodeficiency
  17. 3557
    “…These results not only showed us a comprehensive understanding on the function of ALFs from F. chinensis, but also provided clues for the development of ALFs as potential therapeutic drugs to WSSV.…”
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    Functional Diversity of Anti-Lipopolysaccharide Factor Isoforms in Shrimp and Their Characters Related to Antiviral Activity
  18. 3558
    “…In the present study, we aimed to identify specific biomarkers to assist in the early detection of GDM and give some clues to the possible causes of GDM by comparing serum peptide profile differences between GDM patients and healthy controls. …”
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    Magnetic Bead-Based Serum Peptidome Profiling in Patients with Gestational Diabetes Mellitus
  19. 3559
    “…We reviewed the clinical challenges of PG in order to find helpful clues to improve diagnostic accuracy and the treatment options, namely topical care, systemic drugs, and the new emerging therapies that may reduce morbidity.…”
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    Pyoderma gangrenosum: challenges and solutions
  20. 3560
    “…We suggest that variation in skin chroma and luminance might be used by female helpers and dominant females to identify the timing of birth, while achromatic variations may be used as clues by potential fathers to identify pregnancy stage in females and prepare for paternal burdens as well as to detect oestrus in the early post-partum period.…”
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    Parturition Signaling by Visual Cues in Female Marmosets (Callithrix jacchus)
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