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  1. 3701
    “…We suggest that studying the HGPS also from the electrophysiological point of view might reveal new clues about the normal process of aging.…”
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    BK channel overexpression on plasma membrane of fibroblasts from Hutchinson-Gilford progeria syndrome
  2. 3702
    “…Overall, our study provides several new clues to teixobactin's modes of action.…”
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    Structural studies suggest aggregation as one of the modes of action for teixobactin
  3. 3703
    “…The successful incorporation of informative liquid biopsies, where the liquid biome is interrogated for tumor-associated molecular clues, has the potential to greatly complement the precision-based approach to treatment, and ultimately, to improve clinical outcomes for children with CNS tumors. …”
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    Liquid biopsy for pediatric central nervous system tumors
  4. 3704
    “…Our findings provided novel clues for the treatment of osteoporosis in clinic.…”
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    Gossypol Promotes Bone Formation in Ovariectomy-Induced Osteoporosis through Regulating Cell Apoptosis
  5. 3705
    “…These findings provide important clues to the potential neural basis for cognitive and mental health development in offspring of obese mothers and may lead to the derivation of imaging-based biomarkers for the early identification of risks for timely intervention.…”
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    Maternal Adiposity Influences Neonatal Brain Functional Connectivity
  6. 3706
    “…From a complex systems perspective, both EWS measured in single symptom dynamics and network symptom dynamics at large are hypothesized to provide clues regarding the direction of the transition. …”
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    Can we predict the direction of sudden shifts in symptoms? Transdiagnostic implications from a complex systems perspective on psychopathology
  7. 3707
    “…This study provides useful clues for the further design and discovery of anti-diabetic agents.…”
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    Synthesis and Biological Activity of Isoflavone Derivatives from Chickpea as Potent Anti-Diabetic Agents
  8. 3708
    “…These outcomes provide new insights into horseback riding assets and methodological clues to assess the impact of sport practice.…”
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    Balance control during stance - A comparison between horseback riding athletes and non-athletes
  9. 3709
    “…We begin by highlighting music as an interesting sound stimulus that may provide clues to how temporal patterning in sound drives perception. …”
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    Temporal Processing in Audition: Insights from Music
  10. 3710
    por Wynn, Emily L., Christensen, Alan C.
    Publicado 2018
    “…We systematically identified and compared these repeats, which are important clues to mechanisms of DNA maintenance in mitochondria. …”
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    Repeats of Unusual Size in Plant Mitochondrial Genomes: Identification, Incidence and Evolution
  11. 3711
    “…Understanding the distribution and drivers of microbial life in the sediment may give critical clues on how to search for biosignatures on Mars. …”
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    Subsurface Microbial Habitats in an Extreme Desert Mars-Analog Environment
  12. 3712
    por DiMichele, Donna M.
    Publicado 2018
    “…It further posits that these speed bumps may provide important clues to the mechanistic understanding of both symptom manifestation and resilience within the hemophilia phenotype, as well as opportunities to reconsider and reconfigure the current paradigms for symptom prediction and individualized therapeutic decision making.…”
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    Navigating Speed Bumps on the Innovation Highway in Hemophilia Therapeutics
  13. 3713
    “…Two year after the transplantation, he suffered from severe headache, and head contrast enhanced CT scans did not show clues for brain or skull metastasis. Then he developed hoarseness and dysphagia. …”
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    Solitary nasopharynx metastasis from hepatocellular carcinoma after liver transplantation: A case report
  14. 3714
    “…Aposematic signals combined with intraspecific competition may provide clues to new venomous taxa among mammals.…”
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    Venom in Furs: Facial Masks as Aposematic Signals in a Venomous Mammal
  15. 3715
    “…We have recently elucidated the biosynthesis of fusidane-type antibiotic helvolic acid, which provides us with clues to identify a possible gene cluster for fusidic acid (fus cluster). …”
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    Biosynthesis of clinically used antibiotic fusidic acid and identification of two short-chain dehydrogenase/reductases with converse stereoselectivity
  16. 3716
    “…These findings indicate that enhanced response to emotional stimuli might explain the migraine trigger effect of psychosocial stressors that gradually leads to increased somatosensory response to emotional clues and thus contributes to the progression or chronification of migraine.…”
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    Association between migraine frequency and neural response to emotional faces: An fMRI study
  17. 3717
    “…These results showed that miR-451a may protect from MC-LR-induced DNA damage by down-regulating the expression of p-AKT1, which provides new clues for the diagnosis and therapy policies for liver damage induced by MC-LR.…”
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    Regulation of Microcystin-LR-Induced DNA Damage by miR-451a in HL7702 Cells
  18. 3718
    “…However, the adaptive traits that are involved in the responses to a high soil salinity during reproductive growth are still poorly studied. To identify new clues, we studied the halophyte, Thellungiella salsuginea, and three Arabidopsis accessions, known as tolerant or salt-sensitive. …”
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    Arabidopsis Natural Accessions Display Adaptations in Inflorescence Growth and Vascular Anatomy to Withstand High Salinity during Reproductive Growth
  19. 3719
    “…The peculiar binding mode of the cofactor analogue suggests new clues exploitable for the design of new hTS inhibitors.…”
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    Structural and Functional Characterization of the Human Thymidylate Synthase (hTS) Interface Variant R175C, New Perspectives for the Development of hTS Inhibitors
  20. 3720
    “…The results provide new clues about the half-site reactivity of Enterococcus faecalis TS and the mechanisms underlying the conformational changes occurring in the two enzymes. …”
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    Structural Comparison of Enterococcus faecalis and Human Thymidylate Synthase Complexes with the Substrate dUMP and Its Analogue FdUMP Provides Hints about Enzyme Conformational Variabilities
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