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  1. 4021
    “…We discuss current knowledge regarding the strength of neural activity required to drive endogenous opioid peptide release, clues about how far peptides diffuse from release sites, and their extracellular lifetime after release. …”
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    The life and times of endogenous opioid peptides: Updated understanding of synthesis, spatiotemporal dynamics, and the clinical impact in alcohol use disorder
  2. 4022
    “…The authors demonstrate subtle preoperative MRI findings that might be potential clues to a more infiltrative nature of one PA versus another and present pathological findings supporting this argument. …”
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    Subtle magnetic resonance imaging differences in tegmental pilocytic astrocytomas as a caution against attempting gross-total resection: illustrative cases
  3. 4023
    “…Advances in electron microscopy techniques have provided clues to better understand the structure and composition of identical vascular endothelial glycocalyx. …”
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    The endothelial glycocalyx—All the same? No, it is not
  4. 4024
    “…Since there are no morphological clues capable of making a pathologist suspect a possible mammary origin of a metastatic lesion without adequate clinical information, the histologic diagnosis of brain metastasis from BC is still based on the immunohistochemical expression of mammary gland markers such as GATA-3, ERs, PgRs and HER-2. …”
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    Brain Metastases from Breast Cancer Histologically Exhibit Solid Growth Pattern with at Least Focal Comedonecrosis: A Histopathologic Study on a Monocentric Series of 30 Cases
  5. 4025
    “…Understanding the conditions and mechanisms whereby selective mutations aggravate the pathogenic activities of tau can provide pivotal clues on novel strategies for drug development for frontotemporal dementia and other related neurodegenerative tauopathies, including Alzheimer’s disease.…”
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    Frontotemporal Dementia P301L Mutation Potentiates but Is Not Sufficient to Cause the Formation of Cytotoxic Fibrils of Tau
  6. 4026
    por Hehar, Gurbir, Rahmon, Dalia, Banka, Ajaz
    Publicado 2023
    “…Hypertension and other signs of catecholamine excess, especially in relation to micturition, are important clues. Despite evidence of catecholamine excess in most patients with bladder paraganglioma, the majority are diagnosed after biopsy, indicating a need for improved diagnostic strategies in this patient population. …”
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    Bladder Paraganglioma Associated With Succinate Dehydrogenase A Mutation Presenting as Pelvic Pain
  7. 4027
    “…During recent years, a number of studies with citation bursts and burst keywords (e.g., diabetes, gait, pain, and sensor) have provided clues on the hotspots of prosthetic feet and prosthetic foot trends. …”
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    A Scientometric Analysis and Visualization of Prosthetic Foot Research Work: 2000 to 2022
  8. 4028
    “…This report extends the currently recognized spectrum of KIT-related disorders and provides clues as to the potential etiology of a syndromic form of congenital mastocytosis. …”
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    A Review of the Clinical Features and Management of Systemic Congenital Mastocytosis through the Presentation of An Unusual Prenatal-Onset Case
  9. 4029
    “…Our study provides new clues for alleviating weaning stress in lambs by describing the influence of yeast peptides on the intestinal microflora during weaning.…”
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    Yeast Peptides Improve the Intestinal Barrier Function and Alleviate Weaning Stress by Changing the Intestinal Microflora Structure of Weaned Lambs
  10. 4030
    “…The structures of partially activated IR in complex with aptamers provide clues for understanding the initial activation mechanism. …”
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    A stepwise activation model for the insulin receptor
  11. 4031
    “…These discoveries provide new clues for HSC characterization and functional study.…”
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    Lin(−) PU.1(dim)GATA‐1(−) defines haematopoietic stem cells with long‐term multilineage reconstitution activity
  12. 4032
    “…The mechanical cues of the external microenvironment have been recognized as essential clues driving cell behavior. Although intracellular signals modulating cell fate during sensory epithelium development is well understood, the driving force of sensory epithelium formation remains elusive. …”
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    Varying mechanical forces drive sensory epithelium formation
  13. 4033
    “…These findings provide clues for distinctive cognitive processes (e.g., mentalizing, conflict processing, memory encoding) following the receipt of rejection in girls with high levels of rumination.…”
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    Hooked on a thought: Associations between rumination and neural responses to social rejection in adolescent girls
  14. 4034
    “…It detects subtle changes in the pigment pattern, evaluates vitiligo activity, attempts of re-pigmentation, leucotrichia, and differentiates it from other hypo pigmentary disorders. Most dermatoscopic clues used to assess vitiligo activity are found at the perifollicular level in the center and edge of the lesion. …”
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    Dermatoscopic Patterns in Vitiligo
  15. 4035
    “…This study found that 0.1% CsA administration can relieve symptoms in patients with DED and MGD although there were no definite keratitis clues, such as epithelial erosion. In addition, the conjunctival temperature showed a correlation with symptom improvement.…”
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    Relationship between ocular surface temperature and 0.1% cyclosporine a in dry eye syndrome with meibomian gland dysfunction
  16. 4036
    “…The resistance and resilience of Caribbean octocorals offer clues for the future of coral reefs.…”
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    What makes a winner? Symbiont and host dynamics determine Caribbean octocoral resilience to bleaching
  17. 4037
    “…There seem to be rare results concerning the stability of equilibrium states (or fixed points) of neural networks driven by uncertain processes, and our study in this paper would provide some new research clues in this direction. The conservatism of the main criterion obtained in this paper is reduced by introducing quite general positive definite matrices in our designed Lyapunov–Krasovskii functional.…”
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    Almost Surely Exponential Convergence Analysis of Time Delayed Uncertain Cellular Neural Networks Driven by Liu Process via Lyapunov–Krasovskii Functional Approach
  18. 4038
    “…This work demonstrated the flavonoid-O-glycosyltransferase function of safflower CtUGT4 and showed differences in the affinity for different flavonoid substrates and the regioselectivity of catalytic sites in safflower, both in vivo and in vitro, providing clues for further research regarding the function of UGT genes, as well as new ideas for the cultivation engineering of the directional improvement of effective metabolites in safflower.…”
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    A Muti-Substrate Flavonol O-glucosyltransferases from Safflower
  19. 4039
    “…This study presents preliminary evidence of the functions of US7 and UL56 in the cell-to-cell spread of HSV-1, which will provide important clues to reveal the mechanisms of cell-to-cell spread, and contributes to the clinical drugs development.…”
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    Effects of US7 and UL56 on Cell-to-Cell Spread of Human Herpes Simplex Virus 1
  20. 4040
    “…Furthermore, functional profiling using KEGG provided clues on the impact of Cutibacterium on the host skin barrier. …”
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    Longitudinal study of the interplay between the skin barrier and facial microbiome over 1 year
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