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  1. 4081
    “…RESULTS: From above we found that the molecules NGF, NCAM, MMP, Ach and TGF may have prognostic significance in, and offer clues to the mechanism of CCA neural invasion. CONCLUSIONS: Cholangiocarcinoma's increasing worldwide incidence is especially poignant in view of both the lacking effective therapies, and the fact that it is commonly diagnosed in advanced stages. …”
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    Current research in perineural invasion of cholangiocarcinoma
  2. 4082
    por Porollo, Aleksey, Meller, Jaroslaw
    Publicado 2010
    “…Molecular simulations offer important mechanistic and functional clues in studies of proteins and other macromolecules. …”
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    POLYVIEW-MM: web-based platform for animation and analysis of molecular simulations
  3. 4083
    “…Diagnosis of psychogenic axial jerks was based on clinical clues without additional investigations (n = 8), inconsistent findings at polymyography (n = 15), regular eye blinking preceding jerks (n = 2), or the presence of a Bereitschaftspotential (BP) (n = 9). …”
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    Axial jerks: a clinical spectrum ranging from propriospinal to psychogenic myoclonus
  4. 4084
    “…Information about interactions can hint at molecular causes of diseases, and can provide clues for new therapeutic approaches. Several (usually expensive and time consuming) experimental methods can probe protein - protein interactions. …”
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    Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information
  5. 4085
    “…In conclusion, for the first time, we clarified the relationship between massive vacuolization and autophagic process induced by rare earth oxides and pointed out the size effect of rare earth oxides on the formation of vacuoles, which give clues to further investigation on the mechanisms underlying their biological effects.…”
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    Nano rare-earth oxides induced size-dependent vacuolization: an independent pathway from autophagy
  6. 4086
    por Iwawaki, Takao, Akai, Ryoko, Kohno, Kenji
    Publicado 2010
    “…Comparison of this report with previous reports regarding XBP1 conditional knockout mice might provide some clues for the discovery of the novel functions of IRE1α and XBP1. (196 words)…”
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    IRE1α Disruption Causes Histological Abnormality of Exocrine Tissues, Increase of Blood Glucose Level, and Decrease of Serum Immunoglobulin Level
  7. 4087
    “…The key aim of this study was to explore the group characteristics of patients in different durations of dyslipidemia and provide clues for the management of dyslipidemia in Beijing. …”
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    The characteristics of dyslipidemia patients with different durations in Beijing: a cross-sectional study
  8. 4088
    por Zhang, Zhang, Yu, Jun
    Publicado 2010
    “…BACKGROUND: Understanding the compositional dynamics of genomes and their coding sequences is of great significance in gaining clues into molecular evolution and a large number of publically-available genome sequences have allowed us to quantitatively predict deviations of empirical data from their theoretical counterparts. …”
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    Modeling compositional dynamics based on GC and purine contents of protein-coding sequences
  9. 4089
    “…These findings gave important clues to study of the carcinogenic process in glioblastomas.…”
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    Investigation gene and microRNA expression in glioblastoma
  10. 4090
    “…Therefore, our finding uncovers a direct and functional connection between the Rho GTPase family and the pathway of proteasome biogenesis and provide new clues for deciphering the secrets of spermatogenesis.…”
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    A Novel Testis-specific GTPase Serves as a Link to Proteasome Biogenesis: Functional Characterization of RhoS/RSA-14-44 in Spermatogenesis
  11. 4091
    “…Significantly decreased FA values were consistently observed in the cerebellum of patients, providing fresh evidence and new clues for the important role of cerebellum in IGE with GTCS.…”
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    Cerebellum Abnormalities in Idiopathic Generalized Epilepsy with Generalized Tonic-Clonic Seizures Revealed by Diffusion Tensor Imaging
  12. 4092
    “…This paper aims to provide scientific clues for the selection of special and high quality wild vegetables species. …”
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    An integrated assessment of wild vegetable resources in Inner Mongolian Autonomous Region, China
  13. 4093
    “…Investigations of disease-associated CR events can not only lead to important discoveries about DNA breakage and repair mechanisms, but also offer important clues about the pathologic causes and the diagnostic/therapeutic targets of these diseases. …”
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    dbCRID: a database of chromosomal rearrangements in human diseases
  14. 4094
    “…On the applied side, they may explain the low yield of cloning via somatic cell nuclear transfer, provide clues to some of the problems associated with transdifferentiation, and interfere with individual DNA analysis. …”
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    Are we Genomic Mosaics? Variations of the Genome of Somatic Cells can Contribute to Diversify our Phenotypes
  15. 4095
    “…The goal of this study was to unravel new clues on the biological pathways leading to HIBM by proteomic comparison. …”
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    The Proteomic Profile of Hereditary Inclusion Body Myopathy
  16. 4096
    “…Our study not only provides new clues to understand the role of mRNP biogenesis in preventing genome rearrangements and the mechanism of AID-mediated genome instability, but also shows that, once uracil residues are produced by AID–mediated deamination, these are processed into DSBs and chromosomal rearrangements by the general and conserved DNA repair functions present from yeast to human cells.…”
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    AID Induces Double-Strand Breaks at Immunoglobulin Switch Regions and c-MYC Causing Chromosomal Translocations in Yeast THO Mutants
  17. 4097
    por Xu, Wanghui, Han, Lu, Lin, Zhanglin
    Publicado 2011
    “…The antigenic peptides identified may provide clues for creating peptide vaccines with better accessibility to memory B cells and better induction of cross-neutralizing antibodies than the whole HA protein. …”
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    Screening of Random Peptide Library of Hemagglutinin from Pandemic 2009 A(H1N1) Influenza Virus Reveals Unexpected Antigenically Important Regions
  18. 4098
    “…A study of the temporal-spatial distribution of AQP5 during submandibular gland (SMG) development and in adult tissues might offer further clues to its unknown role during development. In the present work, SMGs from embryonic day (E) 14.5–18.5 and postnatal days (P) 0, 2, 5, 25, and 60 were immunostained for AQP5 and analyzed using light microscopy. …”
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    Localization of AQP5 during development of the mouse submandibular salivary gland
  19. 4099
    “…Metatranscriptomes shed light on microbial metabolism in situ and provide critical clues for directing the culturing of uncultured microorganisms. …”
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    Directed Culturing of Microorganisms Using Metatranscriptomics
  20. 4100
    “…Autism Spectrum Conditions (ASC) are much more common in males, a bias that may offer clues to the etiology of this condition. Although the cause of this bias remains a mystery, we argue that it occurs because ASC is an extreme manifestation of the male brain. …”
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    Online Artículo Texto
    Why Are Autism Spectrum Conditions More Prevalent in Males?
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