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  1. 4281
    “…Transcriptome-scale data can reveal essential clues into understanding the underlying molecular mechanisms behind specific cellular functions and biological processes. …”
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    Transcriptome of interstitial cells of Cajal reveals unique and selective gene signatures
  2. 4282
    “…Our data indicate a conserved function of Snail proteins in embryonic development and tissue regeneration, which may provide clues for CNS repair in the mammals.…”
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    Potential Involvement of Snail Members in Neuronal Survival and Astrocytic Migration during the Gecko Spinal Cord Regeneration
  3. 4283
    “…Our data provide insights into the molecular and functional clues that might help explain, at least in part, the potential therapeutic options of metformin in PCOS patients with uterine dysfunction.…”
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    Metformin Ameliorates Uterine Defects in a Rat Model of Polycystic Ovary Syndrome
  4. 4284
    “…The data will supply important clues to exploit useful genes involved in polysaccharide and alkaloid synthesis.…”
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    Identification and analysis of genes associated with the synthesis of bioactive constituents in Dendrobium officinale using RNA-Seq
  5. 4285
    “…Our established chicken preadipocyte cell lines show great promise as an in vitro model for the investigation of chicken adipogenesis, lipid metabolism, and obesity and its related diseases, and our results also provide clues for immortalizing other avian cell types.…”
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    Immortalization of chicken preadipocytes by retroviral transduction of chicken TERT and TR
  6. 4286
    “…This finding expands the mutation spectrum of PHO, which contributes to improving genetic diagnosis and future genetic counseling, and provides clues to the phenotype-genotype associations.…”
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    Identification of two novel mutations in the SLCO2A1 prostaglandin transporter gene in a Chinese patient with primary hypertrophic osteoarthropathy
  7. 4287
    “…Comparisons of the HIF-1α sequence among cancer-prone and cancer-resistant animals enable us to find out the probable clues towards potential risk factors in the development of cancer.…”
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    Sequence Analysis and Phylogenetic Studies of Hypoxia-Inducible Factor-1α
  8. 4288
    “…The subcellular localization of long noncoding RNAs (lncRNAs) holds valuable clues to their molecular function. However, measuring localization of newly discovered lncRNAs involves time-consuming and costly experimental methods. …”
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    LncATLAS database for subcellular localization of long noncoding RNAs
  9. 4289
    “…Our findings indicate the expression of BnTR1 confers thermoprotective effects on E. coli cells, and it may provide useful clues to engineer thermophilic bacterial strains.…”
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    A novel plant E3 ligase stabilizes Escherichia coli heat shock factor σ(32)
  10. 4290
    “…The presence of autoantibodies in the sera of RA patients has provided many clues to the underlying disease pathophysiology. …”
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    The role of autoantibodies in the pathophysiology of rheumatoid arthritis
  11. 4291
    “…Geo-neutrinos produced by these decays provide important clues about the origin, formation and thermal evolution of our planet, as well as the composition of its interior. …”
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    Exploring the hidden interior of the Earth with directional neutrino measurements
  12. 4292
    “…Although the current study lacks evidence to argue for a lexical tone specific activation pattern, our results provide clues and directions for future investigations on this topic, more sophisticated methods are needed to explore this question in more depth as well.…”
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    A Meta-Analytic Study of the Neural Systems for Auditory Processing of Lexical Tones
  13. 4293
    “…Yet heterogeneous, this vesicle phenotype displayed contact-dependent differences, providing clues about their intended function in cellular communication.…”
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    Induction of a Regulatory Phenotype in CD3+ CD4+ HLA-DR+ T Cells after Allogeneic Mixed Lymphocyte Culture; Indications of Both Contact-Dependent and -Independent Activation
  14. 4294
    “…Therefore, we propose that clues can be found to control the remainder by successfully manipulating the innate immune mechanisms, particularly of nasal and mucosal cavities. …”
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    Bolstering Immunity through Pattern Recognition Receptors: A Unique Approach to Control Tuberculosis
  15. 4295
    “…In addition, our work provided new clues for an improved understanding of how bivalve acclimate themselves to an inconstant environment.…”
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    Conservation and divergence of mitochondrial apoptosis pathway in the Pacific oyster, Crassostrea gigas
  16. 4296
    “…We aim to increase awareness among orthopedic surgeons for clinical clues for systemic cobalt intoxication, even when there is no metal-on-metal bearing surface.…”
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    Fatal Cobalt Toxicity after a Non-Metal-on-Metal Total Hip Arthroplasty
  17. 4297
    “…These results provide a comprehensive framework for the role of Aβ42 in visual loss due to inflammation present with aging and offer some clues for fruitful avenues for the study of healthy aging.…”
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    Markers of Alzheimer's Disease in Primary Visual Cortex in Normal Aging in Mice
  18. 4298
    “…The structure determination and identification of the crystallized protein were derived from several clues: the failures in the Molecular Replacement (MR) trials using LvTrx coordinates as a search model, the unit cell parameters and space group determination, and essentially by the use of the program BALBES. …”
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    First attempts to crystallize a non-homogeneous sample of thioredoxin from Litopenaeus vannamei: What to do when you have diffraction data of a protein that is not the target?
  19. 4299
    “…Pain severity and sleep problems can predict increasing inflammatory markers that can be a clues of intensity of disease. So relieving pain and improved sleep can decrease the intensity of disease.…”
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    Relationship between Sleep, Pain and Inflammatory Markers in Patients with Rheumatoid Arthritis
  20. 4300
    “…The organization of the prefrontal cortex can hold important clues to understanding its functioning. The Cebus apella present cerebral particularities and behavioral and cognitive flexibility, possessing abilities that demonstrate an overlap with those of big primates. …”
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    The prefrontal areas and cerebral hemispheres of the neotropical Cebus apella and its correlations with cognitive processes
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