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4461“…Discovery of a possible shared immune pathway in SLE patients, either with rare or common variants, can provide important clues to better understand this complex disorder, it’s prognosis and can help guide new therapeutic approaches. …”
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4462por Jiang, Yuting, Sun, Qi, Fan, Meihua, Zhang, Xiaolin, Shen, Wang, Xu, Huanzhi, Liao, Zhi“…These results expand the understanding of the functions of PDZ-domain-containing proteins in biomineralization and provide clues for determining the mechanisms of myostracum formation and muscle-shell attachment.…”
Publicado 2020
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4463“…These new findings provide clues into the potential involvement of ILA as the mediator in bifidobacterial host–microbiota crosstalk and neuronal developmental processes.…”
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4464“…We included patients above 15 years of age who exhibited clinical clues and radiological signs of ILD during March 2016 through February 2018 and excluded those who were on tuberculosis treatment, suspected to be suffering from post-infection bronchiectasis, expectant females or had failed to follow-up. …”
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4465por Restivo, Vincenzo, Costantino, Claudio, Amato, Livia, Candiloro, Stefania, Casuccio, Alessandra, Maranto, Marianna, Marrella, Alessandro, Palmeri, Sara, Pizzo, Stefano, Vitale, Francesco, Amodio, Emanuele“…Some clinical characteristics of hospitalization, such as increasing age, are suggestive clues for the impact of preventive strategies, but further research is needed to confirm this relationship.…”
Publicado 2020
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4466por Lu, Liang, Zhang, Yan, He, Qizouhong, Qi, Zengxing, Zhang, Geng, Xu, Wenchao, Yi, Tao, Wu, Gangning, Li, Ruili“…Taken together, these results demonstrate that PtrMTA is involved in drought resistance by affecting the development of trichomes and roots, which will provide new clues for the study of RNA m(6)A modification and expand our understanding of the epigenetic molecular mechanism in woody plants.…”
Publicado 2020
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4467“…A residue from primary tumors leaks into the bloodstream as cell clusters and single cells, providing clues about disease progression and therapeutic response. …”
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4468por Campos, Catarina, Fragoso, Sofia, Luís, Rafael, Pinto, Filipe, Brito, Cheila, Esteves, Susana, Pataco, Margarida, Santos, Sidónia, Machado, Patrícia, Vicente, João B., Costa Rosa, Joaninha, Cavaco, Branca M., Moura, Cecília, Pojo, Marta“…In silico analysis of CDH23 and ARHGEF40 variants provided clues for altered protein structure and function associated with the identified mutations. …”
Publicado 2020
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4469“…The molecular composition and distribution of organic molecules in the lignite provide clues to the understanding of coal structure, which is significant for the environmental emission and development of processing techniques for the clean and high value-added utilizations of such a low-rank and abundant coal resource.…”
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4470por Silva, Aaron, Xiao, Wenwu, Wang, Yan, Wang, Wei, Chang, Heng Wei, Ames, James B., Lam, Kit S., Zhang, Yonghong“…Our study provides new insight into the RGD recognition specificity and valuable clues for rational design of novel αvβ3 antagonists.…”
Publicado 2020
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4471“…Genetic analyses of PA pathway transporter genes (BnMRP5) and their functional characterization might provide clues in better utilizing the available phosphate resources. …”
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4472por Rather, Bilal A., Masood, Asim, Sehar, Zebus, Majid, Arif, Anjum, Naser A., Khan, Nafees A.“…The outcome of the discussion may provide important clues for future research on NO-mediated mitigation of Cu-phytotoxicity.…”
Publicado 2020
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4473por Trono, Paola, Sistigu, Antonella, Palermo, Belinda, Ciliberto, Gennaro, Nisticò, Paola“…A deeper knowledge of the mechanisms and fingerprints involved in natural and acquired resistance is likely to bring clinical benefit to the majority of patients, offering important clues for overcoming drug resistance and boosting the effectiveness of treatment. …”
Publicado 2017
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4474por Ma, Luyuan, Liu, Wenpeng, Xu, An, Ji, Quanbo, Ma, Yongfu, Tai, Yanhong, Wang, Yadong, Shen, Chuan, Liu, Ying, Wang, Tao, Han, Juqiang, Zhao, Caiyan“…Our findings provide new clues regarding the role of ACTR as a prospective sensitizing target for sorafenib therapy in HCC.…”
Publicado 2020
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4475“…This broken gene context provided the aberrant functional clues to study disease genesis. Many tumorigenic fusion genes have retained or lost functional or regulatory domains and these features impacted tumorigenesis. …”
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4476“…In conclusion, this gene signature is a cost-effective tool which could indicate the status of TME to provide more clues in the exploration of new diagnostic and therapeutic strategy.…”
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4477“…Overall, we provide new clues and a basis for investigating the hub proteins of macrophages in response to electric field stimulation.…”
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4478por Lins-Austin, Bridget, Patel, Saajan, Mietzsch, Mario, Brooke, Dewey, Bennett, Antonette, Venkatakrishnan, Balasubramanian, Van Vliet, Kim, Smith, Adam N., Long, Joanna R., McKenna, Robert, Potter, Mark, Byrne, Barry, Boye, Sanford L., Bothner, Brian, Heilbronn, Regine, Agbandje-McKenna, Mavis“…These observations provide clues to the AAV capsid dynamics that facilitate successful infection. …”
Publicado 2020
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4479“…These results advance current knowledge regarding the external layers, especially the dense sheath, involved in the mass transfer in cyanobacteria, and provide new clues concerning the adaptive strategies of cyanobacteria under global climate changes.…”
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4480por Hu, Ke, Wang, Mengmei, Zhao, Yang, Zhang, Yunting, Wang, Tao, Zheng, Zhishui, Li, Xiaochen, Zeng, Shaolin, Zhao, Dong, Li, Honglin, Xu, Ke, Lan, Ke“…This preliminary study on a small-scale compassionate use of Leflunomide provides clues for further understanding of Leflunomide as a potential antiviral drug against COVID-19.…”
Publicado 2020
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