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  1. 4501
    “…The temporal change patterns of laboratory data may provide insightful clues into the whole course of COVID-19. This study aimed to evaluate longitudinal change patterns of key laboratory tests in patients with COVID-19, and identify independent prognostic factors by examining the associations between laboratory findings and outcomes of patients. …”
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    A Prognostic Model to Predict Recovery of COVID-19 Patients Based on Longitudinal Laboratory Findings
  2. 4502
    “…In contrast to the PaLoc, phylogenetic trees of the CdtLoc were more consistent with the core genome phylogenies, but there were clues that CdtLoc can also be exchanged between strains.…”
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    Comparative genomics of Clostridioides difficile toxinotypes identifies module-based toxin gene evolution
  3. 4503
    “…This expanded operon diversity provides clues for deciphering lux operon evolution and propagation within the bacterial domain. …”
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    Diversity and evolution of bacterial bioluminescence genes in the global ocean
  4. 4504
    por Hayden, Patrick J., Harbell, John W.
    Publicado 2020
    “…Among these are the nature and 3D architecture of the substrate on which or in which the cells are grown, physical and mechanical clues from the substrate, cell-cell interactions, and defined biochemical factors that trigger the induction of the 3D organotypic differentiation. …”
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    Special review series on 3D organotypic culture models: Introduction and historical perspective
  5. 4505
    “…Research into the mechanisms of this observation may give important clues to triggering pathogenetic events in MS.…”
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    Stressful life events are associated with the risk of multiple sclerosis
  6. 4506
    “…In combination with future functional studies, the common and distinctive criteria revealed in this study provide important clues for understanding the complexity of host-specific behavior of individual Chlamydia spp.…”
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    Comparative Genome Analysis of 33 Chlamydia Strains Reveals Characteristic Features of Chlamydia Psittaci and Closely Related Species
  7. 4507
    “…These data provide important new clues to canine GDV risk factors and facilitate generation of hypotheses regarding the genetic and molecular underpinnings this syndrome.…”
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    Identification of Genetic Susceptibility Factors Associated with Canine Gastric Dilatation-Volvulus
  8. 4508
    por Aseervatham, Jaya
    Publicado 2020
    “…Changes in cellular architecture by internal clues will affect the cell functions leading to the formation of different protrusions like lamellipodia, filopodia, and invadopodia that help in cell migration eventually leading to metastasis, which is life threatening than the formation of neoplasms. …”
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    Cytoskeletal Remodeling in Cancer
  9. 4509
    por Chua, Marvin Wei Jie
    Publicado 2021
    “…This highlighted the importance of understanding the factors underlying motivation and provided important clues on what clinicians can do to help our patients create a virtuous circle towards positive health outcomes.…”
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    Managing patients with obesity in the post COVID-19 world: Time to sharpen the saw
  10. 4510
    “…This study reveals the metabolites that might be closely associated with the sensory quality attributes of Korla pear, which may provide some clues for promoting the fruit quality in actual production.…”
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    Sensory Quality Evaluation of Korla Pear from Different Orchards and Analysis of Their Primary and Volatile Metabolites
  11. 4511
    “…These results provided fundamental information on intraperitoneal injection with solution buffer. It offered useful clues to further explore the functional mechanism of stress and immunity.…”
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    Impact of Ringer’s Solution Challenge Stress to Immunostimulatory Experiment, Insights From Japanese Flounder
  12. 4512
    “…Therefore, the investigation into osteoblastic differentiation of bone marrow mesenchymal stem cells (BMSCs) will provide more clues for OP treatment. In the present study, we found that microRNA-187-5p (miR-187-5p) played a key role on osteoblastic differentiation, which was significantly upregulated during osteogenic differentiation of BMSCs in mice. …”
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    miRNA-187-5p Regulates Osteoblastic Differentiation of Bone Marrow Mesenchymal Stem Cells in Mice by Targeting ICAM1
  13. 4513
    por Manini, Claudia, López, José I.
    Publicado 2020
    “…The review also updates the literature focusing specifically on the morphological and immunohistochemical clues useful for the diagnosis and some selected molecular studies with prognostic and/or diagnostic implications. …”
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    Unusual Faces of Bladder Cancer
  14. 4514
    “…Overall, our findings further support the potential of patient-specific RTD models and provide evidence of mitochondrial alterations in RTD-related iPSC-derived MNs—emphasizing oxidative stress involvement in this rare disease. We also provide new clues for possible therapeutic strategies aimed at correcting mitochondrial defects, based on the use of antioxidants.…”
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    Mitochondrial Abnormalities in Induced Pluripotent Stem Cells-Derived Motor Neurons from Patients with Riboflavin Transporter Deficiency
  15. 4515
    “…Understanding dsRNA uptake mechanisms will also provide insight into the design and formulation of dsRNAs for improved delivery and provide clues into the development of potential host resistance to these technologies.…”
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    dsRNA Uptake in Plant Pests and Pathogens: Insights into RNAi-Based Insect and Fungal Control Technology
  16. 4516
    “…In this study, we performed small RNA (sRNA) sequencing to explore sRNA profiles of urinary exosomes derived from IMN patients and healthy controls (CON) to provide clues for identifying novel noninvasive sRNA biomarkers for IMN. …”
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    Differential Expression of Urinary Exosomal Small RNAs in Idiopathic Membranous Nephropathy
  17. 4517
    “…Our results provide novel clues about perinatal immunity, underscoring a potential value of IL-8 for the timely detection of infections and suggesting that MIP-1β constitutes an early determinant of sex-specific immunity, which may contribute, e.g., to male’s vulnerability to preterm birth.…”
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    Perinatal Gram-Positive Bacteria Exposure Elicits Distinct Cytokine Responses In Vitro
  18. 4518
    “…Thus, this risk model may serve as a prognostic signature and provide clues for individualized immunotherapy for HNSCC patients.…”
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    Identification of prognostic aging-related genes associated with immunosuppression and inflammation in head and neck squamous cell carcinoma
  19. 4519
    “…These systems are controlled by transcriptional dependent programs that adapt muscle cells to environmental and nutritional clues. Mechanical, oxidative, nutritional and energy stresses, as well as growth factors or cytokines modulate signaling pathways that, ultimately, converge on protein and organelle turnover. …”
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    Mechanisms of muscle atrophy and hypertrophy: implications in health and disease
  20. 4520
    “…Our data provide novel insights into the relationship between the expression of differentially expressed genes and trait segregation and provide clues into the evolution of allopolyploids.…”
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    Analysis of Transcriptional Changes in Different Brassica napus Synthetic Allopolyploids
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