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  1. 4741
    “…Our findings may yield clues as to the molecular mechanism involved in radiation-induced BCC, suggesting that deregulation of ATM-NF-kB signaling and PINK1 gene expression may contribute to BCC radiation carcinogenesis and that the analyzed genes could represent candidate radiation biomarkers associated with radiation-induced BCC.…”
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    Differential Expression of ATM, NF-KB, PINK1 and Foxo3a in Radiation-Induced Basal Cell Carcinoma
  2. 4742
    “…Taken together, this study provides clues into the regulatory roles of the WRKY gene family in N. cadamba.…”
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    Genome-Wide Identification and Expression Analysis of WRKY Gene Family in Neolamarckia cadamba
  3. 4743
    “…This discovery sheds light on more humid conditions of the modern Martian climate and provides critical clues to future exploration missions searching for signs of extant life, particularly at low latitudes with comparatively warmer, more amenable surface temperatures.…”
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    Modern water at low latitudes on Mars: Potential evidence from dune surfaces
  4. 4744
    “…The insight into the interactions between macrophages and other cells, chemokines and growth factors may provide important clues for the development of new, safe and effective immune-targeted therapies for PAH.…”
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    Role of macrophages in pulmonary arterial hypertension
  5. 4745
    “…These findings reveal the therapeutic potential of flubendazole against HCC and provide clues on new repurposed drugs and targets for cancer treatment.…”
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    Drug Repurposing Flubendazole to Suppress Tumorigenicity via PCSK9-dependent Inhibition and Potentiate Lenvatinib Therapy for Hepatocellular Carcinoma
  6. 4746
    “…In conclusion, the panel of six TAAbs can provide potential value for HCC detection, and the strategy to identify novel serological biomarkers can also provide new clues in understanding immunodiagnostic biomarkers.…”
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    Human Proteome Microarray identifies autoantibodies to tumor‐associated antigens as serological biomarkers for the diagnosis of hepatocellular carcinoma
  7. 4747
    “…Phylogenomic analyses characterizing genome-wide gene tree heterogeneity can provide first clues about the extent of ILS and of introgression and thereby into the potential of these processes or (in their absence) the need to invoke novel mutations to underpin convergent evolution. …”
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    A Phylogenomic Assessment of Processes Underpinning Convergent Evolution in Open-Habitat Chats
  8. 4748
    “…Searching for further clues to water-related activities and determining the water source by Zhurong are critical to constrain the volatile evolution history at the landing site.…”
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    In situ analysis of surface composition and meteorology at the Zhurong landing site on Mars
  9. 4749
    “…Notably, the more significant promotion effect of Mn(2+) on the formation of amorphous aggregates provides credible clues to understand the fact that excess exposure to manganese is associated with neurological diseases(.)…”
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    Manganese Ion-Induced Amyloid Fibrillation Kinetics of Hen Egg White-Lysozyme in Thermal and Acidic Conditions
  10. 4750
    “…CONCLUSION: Clinicians should maintain a high level of suspicion for SDAVF and actively review all available radiological imaging for clues, particularly when there is a lack of response to treatment for other causes of myelopathy. …”
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    Spinal Dural Arterio-Venous Fistula: A Vital Differential Diagnosis to Consider for Myelopathy
  11. 4751
    “…We hypothesized that the comparison of longitudinal magnetic resonance imaging data between the two diagnostic groups will provide clues to distinguish diagnosis-specific and transdiagnostic changes. …”
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    Commonalities and differences in ECT-induced gray matter volume change between depression and schizophrenia
  12. 4752
    “…Collectively, our results provide new clues about the assembly and architecture of the paired-end complex formed between TnsB and the transposon DNA, and inform the design of custom payload sequences for genome engineering applications with CAST systems.…”
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    Novel molecular requirements for CRISPR RNA-guided transposition
  13. 4753
    “…CONCLUSIONS: Our results may provide new clues for the prognosis and treatment of PDAC.…”
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    Differential expression and bioinformatics analysis of exosome circRNAs in pancreatic ductal adenocarcinoma
  14. 4754
    “…The key changes in diacylglycerols, fatty acids, and bismonoacylglycerophosphates provided clues that cell signaling disturbances could be associated with curcumin/EGCG intervention. …”
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    Anti-Allergic Effect of Dietary Polyphenols Curcumin and Epigallocatechin Gallate via Anti-Degranulation in IgE/Antigen-Stimulated Mast Cell Model: A Lipidomics Perspective
  15. 4755
    “…In addition, the lack of a comprehensive “early disease clues tracking—personalized treatment system—follow-up” model in hospitals also exacerbates this dilemma. …”
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    New pattern of individualized management of chronic diseases: focusing on inflammatory bowel diseases and looking to the future
  16. 4756
    “…Combination of dsRNA injection and fungal infection showed an additive effect on BPH mortality, which provided clues to develop new pest management strategies against BPH.…”
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    Characterization and transcriptomic analysis of a native fungal pathogen against the rice pest Nilaparvata lugens
  17. 4757
    “…It is our belief that progressing our understanding of the underlying pathogenesis of iDILI will provide mechanistic clues and a method for drug safety screening to better predict liver injury in clinical trials and post-marketing.…”
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    Microphysiological Models for Mechanistic-Based Prediction of Idiosyncratic DILI
  18. 4758
    “…An increasing number of studies have provided clues about eROS action mechanisms, revealing various mechanisms for eROS perception in the apoplast, crosstalk between eROS and reactive nitrogen species, and the contribution of intracellular organelles to cytoplasmic ROS bursts. …”
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    How Extracellular Reactive Oxygen Species Reach Their Intracellular Targets in Plants
  19. 4759
    por Rangachari, Vijayaraghavan
    Publicado 2023
    “…The journey into the past of this phenomenon provides clues to the evolutionary origins of life itself. …”
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    Biomolecular condensates – extant relics or evolving microcompartments?
  20. 4760
    “…Altogether, this study provides important clues for further study on primary bud necrosis.…”
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    Integrated Transcriptome and Metabolome Analysis Revealed the Causal Agent of Primary Bud Necrosis in ‘Summer Black’ Grape
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