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  1. 5061
    por Lima, Bruno P., Shi, Wenyuan, Lux, Renate
    Publicado 2017
    “…This complex set of interactions could have critical implications for the formation and maturation of the oral biofilms in vivo, and could provide clues to the mechanism behind the distribution of organisms inside the human oral cavity.…”
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    Identification and characterization of a novel Fusobacterium nucleatum adhesin involved in physical interaction and biofilm formation with Streptococcus gordonii
  2. 5062
    “…Furthermore, the differences in mortality were most pronounced during the RRT stage of CKD, providing clues for further research. In this regard, Wilmink et al. and Nee et al. point to access to pre-ESRD nephrology care and to the best kidney transplantation options as modifiable factors to be studied in the realm of T3 translational research to improve CKD patient outcomes.…”
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    Does wealth make health? Cherchez la renal replacement therapy
  3. 5063
    “…This study aimed to identify a CIS peripheral blood signature that may provide clues for potential immunomodulatory approaches early in disease. …”
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    Evolving Identification of Blood Cells Associated with Clinically Isolated Syndrome: Importance of Time since Clinical Presentation and Diagnostic MRI
  4. 5064
    “…The illusion provides clues as to how the tactile system represents spatial information. …”
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    An Adaptation-Induced Repulsion Illusion in Tactile Spatial Perception
  5. 5065
    “…This study may provide some clues regarding the adaptation of Bolocera sp. to the deep‐sea environment.…”
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    The mitochondrial genome of a sea anemone Bolocera sp. exhibits novel genetic structures potentially involved in adaptation to the deep‐sea environment
  6. 5066
    “…These results provide us with important clues to investigate the regulatory roles of miRNAs in rice female gametophyte abortion.…”
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    Genetic Subtraction Profiling Identifies Candidate miRNAs Involved in Rice Female Gametophyte Abortion
  7. 5067
    “…In conclusion, our study highlights the significance of the editing function of LeuRS and provides clues for understanding the intracellular stress protective mechanisms that are triggered in aaRS editing-deficient organisms.…”
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    Self-protective responses to norvaline-induced stress in a leucyl-tRNA synthetase editing-deficient yeast strain
  8. 5068
    “…The clade-specific features of the mycobacteria RNAP provide clues to the profound instability of mycobacteria RPo compared with E. coli.…”
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    Structural insights into the mycobacteria transcription initiation complex from analysis of X-ray crystal structures
  9. 5069
    “…The SEM analysis provided valuable clues for further investigations in understanding the process of tumorigenesis in HCC.…”
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    Epigenome-wide association study in hepatocellular carcinoma: Identification of stochastic epigenetic mutations through an innovative statistical approach
  10. 5070
    “…These findings provide important mechanistic clues that help explain both B cell lymphocytosis and humoral immunodeficiency in BENTA disease.…”
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    Intrinsic Plasma Cell Differentiation Defects in B Cell Expansion with NF-κB and T Cell Anergy Patient B Cells
  11. 5071
    “…Gene expression patterns assayed across development can offer key clues about a gene’s function and regulatory role. …”
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    FlyExpress 7: An Integrated Discovery Platform To Study Coexpressed Genes Using in Situ Hybridization Images in Drosophila
  12. 5072
    por Kim, Jieun, Jung, Youngmi
    Publicado 2017
    “…In addition, currently available animal models of RILD are reviewed, focusing on similarities with human RILD and clues to understanding the mechanisms of RILD progression. …”
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    Radiation-induced liver disease: current understanding and future perspectives
  13. 5073
    “…Within this functional spectrum diverse and often opposing phenotypes are displayed which are dictated by environmental clues and depend on highly plastic transcriptional programs. …”
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    Multidimensional pooled shRNA screens in human THP-1 cells identify candidate modulators of macrophage polarization
  14. 5074
    por Kamboj, Amrit K, Oxentenko, Amy S
    Publicado 2017
    “…Many mimickers of celiac disease have clues to the underlying diagnosis, and many have a targeted therapy. …”
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    Clinical and Histologic Mimickers of Celiac Disease
  15. 5075
    “…These predictions were validated via physiological characterization, showing the predictive power of metabolic network reconstructions to provide new clues about the metabolic versatility of Malassezia.…”
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    Lipid Metabolic Versatility in Malassezia spp. Yeasts Studied through Metabolic Modeling
  16. 5076
    “…Understanding these evolutionary traits may provide important clues for the development of effective therapies to treat P. aeruginosa infections. …”
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    The rapid in vivo evolution of Pseudomonas aeruginosa in ventilator-associated pneumonia patients leads to attenuated virulence
  17. 5077
    “…While fast explorers may collect less information from the environment, slow explorers (reactive birds) seem to pay attention to environmental clues and collect detailed information. We provided evidence that the rate of habituation of behavioural responses, a proxy of cognitive abilities, may be affected by different factors and in a complex way.…”
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    Learning speed is affected by personality and reproductive investment in a songbird
  18. 5078
    “…Furthermore, the PHP-exonuclease shows a striking similarity to E. coli endonuclease IV, which provides clues regarding the mechanism of action. Altogether, this work provides important insights into the PHP-exonuclease and reveals unique properties that make it an attractive target for novel anti-mycobacterial drugs.…”
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    High-fidelity DNA replication in Mycobacterium tuberculosis relies on a trinuclear zinc center
  19. 5079
    “…The results of the study provide important clues for certain transient side effects of DBS and for development of new adaptive stimulation paradigms.…”
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    Novel Stimulation Paradigms with Temporally-Varying Parameters to Reduce Synchronous Activity at the Onset of High Frequency Stimulation in Rat Hippocampus
  20. 5080
    “…Pangenome analyses of the Serratia sp. isolates offered clues linking Type VI secretion system effector–immunity proteins from the Tai4 sub-family to the symbiotic lifestyle.…”
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    Comparative Genomics of Facultative Bacterial Symbionts Isolated from European Orius Species Reveals an Ancestral Symbiotic Association
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