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  1. 5141
    “…Comparing the expression patterns of duplicate genes gives clues as to whether any of these evolutionary processes have occurred. …”
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    A likelihood ratio test for changes in homeolog expression bias
  2. 5142
    “…In other words, valuable clues for future clinical studies of cocoa health benefits are highlighted as anticancer agent in this study once validation studies are carried out.…”
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    Investigation of health benefits of cocoa in human colorectal cancer cell line, HT-29 through interactome analysis
  3. 5143
    “…Besides that, literature provides clues that prematurity affects growth and development. …”
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    The Preterm Gut Microbiota: An Inconspicuous Challenge in Nutritional Neonatal Care
  4. 5144
    “…The findings provide us clues to understand epigenetic modification of RNA in ccRCC.…”
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    Gene signatures and prognostic values of m6A regulators in clear cell renal cell carcinoma – a retrospective study using TCGA database
  5. 5145
    “…Metabolites such as potassium and sodium ion may provide valuable clues for early diagnostic and therapeutic targets for AF.…”
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    Combined metabolic, phenomic and genomic data to prioritize atrial fibrillation-related metabolites
  6. 5146
    por Martín-Olalla, José María
    Publicado 2019
    “…The phase of the sleep/wake cycle is then governed by natural trends and no clues of misalignment are revealed.…”
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    Seasonal synchronization of sleep timing in industrial and pre-industrial societies
  7. 5147
    “…Plants have evolved several mechanisms for sensing increased irradiance, involving signal perception by photoreceptors (cryptochromes), and subsequent biochemical (reactive oxygen species, ROS) and metabolic clues to transmit the signals. This results in the increased expression of heat‐shock response genes and of the transcription factor LONG HYPOCOTYL 5 (HY5, mediated by the cryptochrome photoreceptor 1, CRY1). …”
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    Photosynthetic response to increased irradiance correlates to variation in transcriptional response of lipid‐remodeling and heat‐shock genes
  8. 5148
    “…Here, we summarize the strong potential of miR-21 in pulmonary remodeling and provide novel clues for further research in this area.…”
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    Pleiotropic microRNA-21 in pulmonary remodeling: novel insights for molecular mechanism and present advancements
  9. 5149
    “…Further studies will provide clear clues for effectively treating UL with CRSR.…”
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    Transcriptional profiling of uterine leiomyoma rats treated by a traditional herb pair, Curcumae rhizoma and Sparganii rhizoma
  10. 5150
    “…This study provides an efficient method for QQ enzyme modification and gives us new clues for further investigation on the catalytic mechanism of QQ lactonase.…”
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    Activity Improvement and Vital Amino Acid Identification on the Marine-Derived Quorum Quenching Enzyme MomL by Protein Engineering
  11. 5151
    “…We thus aimed to identify common molecular biomarkers and pathways in IS and AD that can help predict the progression of these diseases and provide clues to important pathological mechanisms. Materials and Methods: We have analyzed the microarray gene expression datasets of IS and AD. …”
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    Discovering Biomarkers and Pathways Shared by Alzheimer’s Disease and Ischemic Stroke to Identify Novel Therapeutic Targets
  12. 5152
    “…Saints are only sometimes labeled with their names. The clues to their identity are rather given in their appearance or in what they are holding. …”
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    Saint Rita of Cascia: Patron Saint for Women with Frontal Fibrosing Alopecia?
  13. 5153
    “…Oligomerization is driven by metallophilic Hg⋅⋅⋅Hg interactions. Our results provide clues as to why Hg has higher affinity for the α than the β domain. …”
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    Mercury(II) Binding to Metallothionein in Mytilus edulis revealed by High Energy‐Resolution XANES Spectroscopy
  14. 5154
    “…Few GWAS hits in human genetics for neuropsychiatric disorders to date have afforded such mechanistic clues. Further, the potential for genetic distinction of susceptibility to BD from other neuropsychiatric disorders with overlapping clinical traits holds promise for improved diagnostics and treatment of this devastating illness.…”
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    Genetic variants in the bipolar disorder risk locus SYNE1 that affect CPG2 expression and protein function
  15. 5155
    “…CONCLUSION: We provide the first evidence that the functionality of frozen stallion spermatozoa can be potentially improved after thawing through the activation of pro survival pathways, providing new clues for improving current sperm biotechnology.…”
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    Rosiglitazone in the thawing medium improves mitochondrial function in stallion spermatozoa through regulating Akt phosphorylation and reduction of caspase 3
  16. 5156
    “…In conclusion, our results provide clues for the metabolic derangements in diabetic central neuropathy among T2DM patients; however, their clinical significance requires further exploration.…”
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    (1)H Nuclear Magnetic Resonance (NMR)-Based Cerebrospinal Fluid and Plasma Metabolomic Analysis in Type 2 Diabetic Patients and Risk Prediction for Diabetic Microangiopathy
  17. 5157
    “…Four TFs (PAX4, POU2F1, ELK1 and NKX2‐5) were concluded to play a role in IS. Our finding provided clues for exploring mechanism and developing novel diagnostic and therapeutic strategies for IS.…”
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    Identification of key genes and upstream regulators in ischemic stroke
  18. 5158
    “…The biomarkers identified can bring new clues to basic researches.…”
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    A Noninvasive Prediction Nomogram for Lymph Node Metastasis of Hepatocellular Carcinoma Based on Serum Long Noncoding RNAs
  19. 5159
    “…This work provides some clues for further exploring 2D SiE/MX(2) heterostructures involving tailored photoelectric properties.…”
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    Transport and Photoelectric Properties of 2D Silicene/MX(2) (M = Mo, W; X = S, Se) Heterostructures
  20. 5160
    “…Now that the genetic and molecular mechanisms of NCMD are known, these may provide clues into the pathogenesis of CT.…”
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    Congenital toxoplasmosis as one phenocopy of North Carolina Macular Dystrophy (NCMD/MCDR1)
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