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5161“…The characterization of Pdd’s secretome may hold additional clues because it may lead to the identification of proteases activating PhlyP’s pro-form. …”
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5162por Uetrecht, Jack“…Studies of the subclinical innate immune response to drugs may provide important mechanistic clues and provide a method to screen drugs for their potential to cause IDILI.…”
Publicado 2019
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5163“…The dermatoscopic images revealed circular or quasi-circular whitish amorphous structure with a central brownish keratin plug, providing the diagnostic clues of T. marneffei infection. Therefore, a skin scrapings culture, skin biopsy and serological detection for human immunodeficiency virus (HIV) were performed. …”
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5164por Baker, David, Nutma, Erik, O'Shea, Helen, Cooke, Anne, Orian, Jacqueline M., Amor, Sandra“…INTERPRETATION: Although MOG (35‐55)‐induced EAE in NOD mice may provide some clues about approaches to block neurodegeneration associated with the inflammatory penumbra as lesions form, it should not be used to justify trials in people with nonactive, progressive MS. …”
Publicado 2019
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5165por Gorodetskii, Artem A., Eubank, Timothy D., Driesschaert, Benoit, Poncelet, Martin, Ellis, Emily, Khramtsov, Valery V., Bobko, Andrey A.“…A noninvasive procedure that enables visualization of these parameters may provide unique information about mechanisms of tumor pathophysiology and provide clues to new treatment targets. In this research, we present a multiparametric imaging method allowing for concurrent mapping of pH, spin probe concentration, pO(2), and Pi using a single contrast agent and Overhauser-enhanced magnetic resonance imaging technique. …”
Publicado 2019
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5166“…The results of the present study identified lncRNA OECC as a novel regulator of lung cancer progression and provided new clues for the clinical treatment of lung cancer.…”
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5167por Peng, Huiyun, Ishida, Keishi, Sugimoto, Yuki, Jenke-Kodama, Holger, Hertweck, Christian“…Mutational and functional analyses of the polyketide-tailoring cytochrome P450 monooxygenases, and PKS phylogenies give contradictory clues on potential evolutionary scenarios (generalist-to-specialist enzyme evolution vs. most parsimonious ancestor). …”
Publicado 2019
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5168“…Its rate and its development over time hold important clues to the behavior of many body systems. For example, gas particles constantly change their position and surrounding particles, while in solids one expects the motion of the atoms to be limited by a fixed set of neighboring atoms. …”
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5169“…The evidence of interaction between VCM exposure and other known liver carcinogens such as alcohol and chronic viral infection provides clues for the health surveillance of exposed workers. …”
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5170por Wang, Xuning, Xu, Maolin, Yan, Yongfeng, Kuang, Yanshen, Li, Peng, Zheng, Wei, Liu, Hongyi, Jia, Baoqing“…These findings provide new clues with prognostic and therapeutic implications in gastric cancer.…”
Publicado 2019
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5171“…Social media data can help identify common locations referenced in vaping-related discussions and offer clues about where individuals vape. These insights can strengthen current tobacco regulations and prioritize new policies to improve public health. …”
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5172Body composition, dual-energy X-ray absorptiometry and obesity: the paradigm of fat (re)distributionpor Ponti, Federico, Plazzi, Andrea, Guglielmi, Giuseppe, Marchesini, Giulio, Bazzocchi, Alberto“…CONCLUSION: Serial DXA measurements could provide a comprehensive assessment of body compartments, independent of changes in classic anthropometry (body mass index and waist circumference), identifying a significant redistribution of lean and fat mass and providing clues to explain changes in cardiovascular risk profile.…”
Publicado 2019
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5173por Yoo, Seung-Yeon, Lee, Ji-Ae, Shin, Yunjoo, Cho, Nam-Yun, Bae, Jeong Mo, Kang, Gyeong Hoon“…In addition, we identified some histologic and molecular features that might be clues to elucidate the role of SMAD4 in colorectal tumorigenesis and progression.…”
Publicado 2019
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5174por Holland, Sophie I., Edwards, Richard J., Ertan, Haluk, Wong, Yie Kuan, Russell, Tonia L., Deshpande, Nandan P., Manefield, Michael J., Lee, Matthew“…It includes an abundance of methyltransferases, which may provide clues to the basis of its DCM metabolism, as well as potential to metabolise additional methylated substrates such as quaternary amines. …”
Publicado 2019
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5175por Feng, Siqi, Wang, Huan, Wang, Ying, Sun, Runbin, Xie, Yuan, Zhou, Zhu, Wang, Hong, Aa, Jiye, Zhou, Fang, Wang, Guangji“…Therefore, increased content of 3‐HB induced by PPARα activation in the liver partially contributed to the antitumor effect of apatinib. It may provide clues to another potential mechanism underlying the antitumor effect of apatinib besides its antiangiogenic effect through inhibiting vascular endothelial growth factor receptor 2.…”
Publicado 2019
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5176“…These findings may provide helpful clues to understand the mechanism of brain functions.…”
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5177por Nayfach, Stephen, Shi, Zhou Jason, Seshadri, Rekha, Pollard, Katherine S., Kyrpides, Nikos C.“…Finally, our analysis revealed that uncultured gut species have undergone genome reduction that has resulted in the loss of certain biosynthetic pathways, which may offer clues for improving cultivation strategies in the future.…”
Publicado 2019
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5178por Lan, Qiong, Xie, Tong, Jin, Xiaoye, Fang, Yating, Mei, Shuyan, Yang, Guang, Zhu, Bofeng“…BACKGROUND: Profiling of mitochondrial DNA is surely to provide valuable investigative clues for forensic cases involving highly degraded specimens or complex maternal lineage kinship determination. …”
Publicado 2019
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5179por Fukushi, Keisuke, Sekine, Yasuhito, Sakuma, Hiroshi, Morida, Koki, Wordsworth, Robin“…These properties of surface waters on early Mars reflect palaeoenvironments, and thus provide clues on the palaeoclimate and habitability. Here we constrain these properties of pore water within lacustrine sediments of Gale Crater, Mars, using smectite interlayer compositions. …”
Publicado 2019
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5180“…Finally, providers showed little response to differences in patient identity, but showed strong responses to differences in case presentation that give some clues as to the reasons for these behaviors.…”
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