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5221por Huang, Angkana T., Garcia-Carreras, Bernardo, Hitchings, Matt D.T., Yang, Bingyi, Katzelnick, Leah C., Rattigan, Susan M., Borgert, Brooke A., Moreno, Carlos A., Solomon, Benjamin D., Rodriguez-Barraquer, Isabel, Lessler, Justin, Salje, Henrik, Burke, Donald, Wesolowski, Amy, Cummings, Derek A.T.“…While studies of SARS-CoV-2 are necessary to determine immune responses to it, evidence from other coronaviruses can provide clues and guide future research.…”
Publicado 2020
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5222“…The introduction and innovation of nanotechnology offers inspiration and clues for the development of new strategies to treat vitiligo. …”
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5223“…Here we report two forms of DENV serotype 2 (DENV2) NS5 crystal structures representing two conformational states with defined analogies to the JEV-mode and DENV3-mode conformations, respectively, demonstrating the conservation of both conformation modes and providing clues for how different conformational states may be interconnected. …”
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5224por Jaime-Lara, Rosario B., Koons, Brittany C., Matura, Lea Ann, Hodgson, Nancy A., Riegel, Barbara“…Better understanding its nature could provide important clues regarding the mechanisms underlying fatigue and aid in developing more effective therapeutic interventions to decrease fatigue and improve quality of life. …”
Publicado 2019
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5225por MEIGOUNI, Masoumeh, MAKKI, Mahsasadat, HANILOO, Ali, ASKARI, Zeynab, MOBEDI, Iraj, NADDAF, Saied Reza, BOENKE, Nicole, STOLLNER, Thomas, AALI, Abolfazl, HEIDARI, Zahra, MOWLAVI, Gholamreza“…CONCLUSION: The presence of two different nematodes in the equids coprolites provide clues of the burden of helminths infection on working animal at the Sassanid time and demonstrates the appropriate preservation condition of biological remains in the ancient salt mine of Chehrabad as well.…”
Publicado 2020
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5226por Xu, Yongzi, Liu, Yanhui, Li, Zhenrong, Li, Hao, Li, Xiqing, Yan, Lei, Mao, Jiayan, Shen, Jian, Chen, Wei, Xue, Fei“…In conclusion, our study provides new clues for further clinical treatment of sorafenib-resistant liver cancer patients.…”
Publicado 2020
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5227por Zhang, Hongzhe, Liu, Lingshuang, Jiang, Chunmiao, Pan, Keqing, Deng, Jing, Wan, Chunyan“…MMP9 plays a protective role in LPS-induced inflammation, thereby providing new clues to the prevention and treatment of apical periodontitis.…”
Publicado 2019
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5228“…CONCLUSIONS: The present study identified a pool of candidate biomarkers such as Cdk1, C3, Mapk12, Agt, Adipoq, Cxcl2, and Mmp9 and molecular mechanisms which may be involved in the early phase of experimental DPN. The findings provide clues for exploring new strategies for the early diagnosis and treatment of DPN.…”
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5229por Gropman, Andrea, Uittenbogaard, Martine, Brantner, Christine A., Wang, Yue, Wong, Lee-Jun, Chiaramello, Anne“…In conclusion, our comprehensive genetic and metabolic analyses suggest an oligogenic inheritance among the nuclear and mitochondrial variants for the mitochondrial etiology of proband's atypical form of AHC, thereby providing critical insight in terms of genetic clues and bioenergetic deficit. This approach also improves the diagnostic process of atypical form of AHC with an unclear genotype-phenotype correlation to personalize therapeutic interventions.…”
Publicado 2020
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5230por Beato, Silvia, Marques, Carlos, Laizé, Vincent, Gavaia, Paulo J., Fernández, Ignacio“…The present work provides new and basic molecular clues evidencing how VK metabolism in marine fish is sensitive to nutritional and environmental conditions.…”
Publicado 2020
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5231“…Overall, these findings provide clues for further understanding of the NbrgsCaM family genes in regulating plant growth and development under biotic stress and environmental stimulation.…”
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5232por Simon, Sandra J., Tschaplinski, Timothy J., M. LeBoldus, Jared, Keefover‐Ring, Ken, Azeem, Muhammad, Chen, Jin‐Gui, Macaya‐Sanz, David, MacDonald, William L., Muchero, Wellington, DiFazio, Stephen P.“…These genomic signatures provide important clues about the complexities of plant/biotic stress interactions and evolution. …”
Publicado 2020
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5233por Kou, Jianqiang, Liu, Guoming, Liu, Xiangyun, Li, Tianmi, Wei, Ying, Sun, Yuanliang, Wang, Ting, Wang, Yingzhen, Zheng, Xiujun“…Taken together, these results revealed the expression profiles of circRNAs and the potential functions of the differentially expressed circRNAs in the spinal ligament tissue of patients with AS, which may provide new clues for understanding the mechanisms associated with AS, and proceed to identify novel potential molecular targets for the diagnoses and treatment of AS.…”
Publicado 2020
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5234por Wilde, Danielle“…I speak to the merits of post-disciplinary and hybrid strategies, and look to science for clues about how to respond to twenty-first-century challenges through design. …”
Publicado 2020
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5235“…Overall, this paper offers clues on how bike sharing, and cycling in general, can support the transition to a post-coronavirus society.…”
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5236por Zhang, Jing, Wu, Dan, He, Yongxing, Li, Lanlan, Liu, Shanhui, Lu, Jianzhong, Gui, Huiming, Wang, Yuhan, Tao, Yan, Wang, Hanzhang, Kaushik, Dharam, Rodriguez, Ronald, Wang, Zhiping“…The results of this study not only can provide useful information about the interaction mechanism between rapamycin and FKBP51, but also can provide new clues for the treatment of prostate cancer and castration-resistant prostate cancer.…”
Publicado 2020
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5237“…The present study revealed the overall perspective of methylation-driven genes in KIRC and can help in the evaluation of the prognosis of KIRC patients and provide new clues for further study.…”
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5238por DAMAR, Çağrı, DERİNKUYU, Betül Emine, KILIÇKAYA, Muazzez Asburçe Bike Olgaç, ÖZTÜRK, Mehmet, ÖZTUNALI, Çiğdem, ALIMLI, Ayşe Gül, BOYUNAĞA, Öznur Leman, UÇAR, Murat, EZGÜ, Fatih Süheyl, TÜMER, Leyla, BÖRCEK, Alp Özgün, SIĞIRCI, Ahmet“…CONCLUSION: The abnormal cranial MRI findings of the MPS patients, including the newly identified IHOMS, may provide diagnostic clues to differentiate the type of the disease in radiological imaging.…”
Publicado 2020
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5239“…Efforts to standardize these findings and explore relationships between genotype and phenotype will provide important clues into the evolutionary and mechanistic bases of physiological adaptations to environmental hypoxia.…”
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5240por Yao, Meng-sha, Zhou, Li-che, Tan, Yu-yan, Jiang, Hong, Chen, Zhi-chun, Zhu, Lin, Luo, Ning-di, Wu, Quan-zhou, Kang, Wen-yan, Liu, Jun“…There is decreased functional connectivity among the insula, supplementary motor area and middle frontal gyrus with structural abnormalities between the left insula and the left supplementary motor area; these changes in brain connectivity are probably among the causes of gait dysfunction in PDPA and provide some clues regarding the pathogenic mechanisms of PDPA.…”
Publicado 2020
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