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  1. 5361
    “…Moreover, anti-CD3 and anti-CD8 stains are recommended in patients not responding to the gluten-free diet (GFD) to confirm a diagnosis of Refractory Celiac Disease (RCeD). Diagnostic clues about the differential diagnosis of both CeD and RCeD have also been rendered.…”
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    Histopathology of Celiac Disease. Position Statements of the Italian Group of Gastrointestinal Pathologists (GIPAD-SIAPEC)
  2. 5362
    “…BACKGROUND: Urinary oxalate can provide important clues for the screening and monitoring of children with primary hyperoxaluria (PH), which is a potentially life‐threatening condition. …”
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    Evaluation of a high‐performance liquid chromatography method for urinary oxalate determination and investigation regarding the pediatric reference interval of spot urinary oxalate to creatinine ratio for screening of primary hyperoxaluria
  3. 5363
    “…HIV superinfection elicits bnAbs more frequently than single infection, providing clues of how to elicit such responses. We used longitudinal antibody sequencing and structural studies to characterize bnAb development from a superinfection case. …”
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    Functional development of a V3/glycan-specific broadly neutralizing antibody isolated from a case of HIV superinfection
  4. 5364
    “…Therefore, investigating the mtDNA receptors and their signaling pathways might provide important clues for therapeutic interventions.…”
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    Through DNA sensors and hidden mitochondrial effects of SARS-CoV-2
  5. 5365
    “…Our results provide a reasonable and systematic interpretation for the connection between magnetism and superconductivity and give clues for achieving spin-to-superconducting switching materials with certain crystal features.…”
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    Pressure-Induced Transition from Spin to Superconducting States in Novel MnN(2)
  6. 5366
    “…This report provides new clues regarding the mechanisms of the beneficial effects of rifaximin, suggesting that early rifaximin treatment could prevent neurological impairment in patients with steatohepatitis.…”
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    Rifaximin Prevents T-Lymphocytes and Macrophages Infiltration in Cerebellum and Restores Motor Incoordination in Rats with Mild Liver Damage
  7. 5367
    “…In conclusion, our results provide important clues for the detailed replication mechanism of rabies virus and the discovery of therapeutic targets.…”
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    Function of Host Protein Staufen1 in Rabies Virus Replication
  8. 5368
    “…Altogether, our plasma membrane profiling of human macrophages provides clues to understand how viruses evade the immune system and identified novel cell surface receptors targeted by HCMV.…”
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    Comprehensive Analysis of Human Cytomegalovirus- and HIV-Mediated Plasma Membrane Remodeling in Macrophages
  9. 5369
    “…Herein, we review the pathways involved in the pathogenesis of LGLL, including refractory cases, inferring clues as to the potentially actionable targets. ABSTRACT: Large Granular Lymphocyte Leukemia (LGLL) is a rare, chronic lymphoproliferative disorder of effector cytotoxic T-cells, and less frequently, natural killer (NK) cells. …”
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    Large Granular Lymphocytic Leukemia: From Immunopathogenesis to Treatment of Refractory Disease
  10. 5370
    “…METHODS: To investigate the details of these two functions in Chinese elderly people and to try to find some early recognition and intervention clues, data of MMSE test and usual gait speed from 4487 elderly people from seven provinces in China were analysed. …”
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    Characteristics of decline in cognition and locomotion among the elderly in seven provinces of China
  11. 5371
    “…Changes in the expression levels of key proteins were verified by western blot assays. These data provided clues to improve the understanding of the functional capacity associated with NSC transplantation in Alzheimer’s disease treatment. …”
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    Neural stem cell transplantation alleviates functional cognitive deficits in a mouse model of tauopathy
  12. 5372
    “…BACKGROUND: Modulation of behavior and physiology by dietary perturbations early in life can provide clues to the pathogenesis of adult diseases. We tested the hypothesis that a period of early protein supplementation modulates sympathetic nervous system activity demonstrated indirectly by an increase in active sleep state distribution in very low birth weight (VLBW) infants. …”
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    The Interaction between Diet and Neurobehavior in Very Low Birth Weight Infants
  13. 5373
    “…Our results challenge current models for HAp mineralization in bone and the role of citrate, offering new clues to help answer the long-standing question as to why natural evolution favored HAp as the mineral phase in bone.…”
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    Citrate Stabilizes Hydroxylapatite Precursors: Implications for Bone Mineralization
  14. 5374
    “…We then use current advances to elucidate the logic and molecular architecture of temporal networks that comprise autonomous clocks, providing important clues as to how these clocks may have evolved to run independently and, sometimes at the cost of redundancy, have strongly coupled to run under the full command of the cell cycle and/or the circadian clock. …”
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    Autonomous clocks that regulate organelle biogenesis, cytoskeletal organization, and intracellular dynamics
  15. 5375
    “…This study hopes to provide meaningful clues and a scientific basis for policymakers regarding effective interventions against dengue transmission, even during outbreaks.…”
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    Interaction of climate and socio-ecological environment drives the dengue outbreak in epidemic region of China
  16. 5376
    “…Here, in this review, we will illustrate the pharmacological activities of sinomenine in cardio-cerebrovascular system and elaborate the underlying mechanisms, as well as give an overview of the potential therapeutic roles of sinomenine in cardio-cerebrovascular diseases, trying to provide clues and bases for its clinical usage.…”
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    Sinomenine in Cardio-Cerebrovascular Diseases: Potential Therapeutic Effects and Pharmacological Evidences
  17. 5377
    “…These analyses offered new clues regarding effector molecules involved in prostate cancer development, insights that are supported by the demonstration of increased expression levels of the eight identified proteins in prostate cancer patients and assessments of the progression-free interval. …”
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    Characterization of Proteins Regulated by Androgen and Protein Kinase a Signaling in VCaP Prostate Cancer Cells
  18. 5378
    por Serrano, Mercedes
    Publicado 2021
    “…In this paper, the recent SLE experiences of two PMM2-CDG patients are examined to provide clinical clues to help improve diagnosis through a clinical constellation of symptoms and a clinical definition, but also to support a neuroelectrical hypothesis as an underlying mechanism. …”
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    Stroke-Like Episodes in PMM2-CDG: When the Lack of Other Evidence Is the Only Evidence
  19. 5379
    “…This rapid expansion of P.1 but suppression of B.1.351 expands our understanding of population-level VOC patterns and might provide clues to fitness determinants for emerging VOCs.…”
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    Rapid Increase in SARS-CoV-2 P.1 Lineage Leading to Codominance with B.1.1.7 Lineage, British Columbia, Canada, January–April 2021
  20. 5380
    “…Interestingly, common or unique pathways and biofunctions were also identified, providing novel mechanistic clues about each neurological disease at olfactory level. …”
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    Online Artículo Texto
    Tackling the Biological Meaning of the Human Olfactory Bulb Dyshomeostatic Proteome across Neurological Disorders: An Integrative Bioinformatic Approach
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