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  1. 5381
    “…Our results provide new evolutionary insight into the BBX gene family in cultivated strawberry and clues regarding their function in flowering time regulation in plants.…”
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    An Evolutionary Analysis of B-Box Transcription Factors in Strawberry Reveals the Role of FaBBx28c1 in the Regulation of Flowering Time
  2. 5382
    “…The placenta is a complex interface organ that may hold clues to the reasons for fetal, neonatal or maternal demise. …”
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    A practical guide to placental examination for forensic pathologists
  3. 5383
    por Wu, Jinfeng, Zhang, Lei, Wang, Xing
    Publicado 2021
    “…Collectively, we propose to provide a comprehensive overview of the role of male sex hormones during multiple phases in the life cycle of different human viruses, which may be partly responsible for the sex-specific prevalence, severity and mortality of some diseases, therefore, may provide clues to develop more efficient prevention and treatment strategies for high-risk populations.…”
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    Host Sex Steroids Interact With Virus Infection: New Insights Into Sex Disparity in Infectious Diseases
  4. 5384
    “…Our results of this study may help to elucidate the molecular properties of the COBRA gene family and provide informative clues for high stem-breaking resistance studies.…”
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    Genome-wide identification and expression profiling of the COBRA-like genes reveal likely roles in stem strength in rapeseed (Brassica napus L.)
  5. 5385
    “…We demonstrated that doxycycline-mediated inhibition of MMPs rescues in hEDS cells a control-like ECM organization and induces a partial reversal of their myofibroblast-like features, thus offering encouraging clues for translational studies confirming MMPs as a potential therapeutic target in hEDS with the expectation to improve patients’ quality of life and alleviate their disabilities.…”
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    Matrix Metalloproteinases Inhibition by Doxycycline Rescues Extracellular Matrix Organization and Partly Reverts Myofibroblast Differentiation in Hypermobile Ehlers-Danlos Syndrome Dermal Fibroblasts: A Potential Therapeutic Target?
  6. 5386
    “…By highlighting the importance of trait anxiety and depression when considering the impact of tDCS on the attentional networks, this study fulfills a valuable niche in clinical neuroscience, wherein preclinical data provide critical clues for larger, more definitive future translational efforts.…”
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    The Impact of Anodal tDCS on the Attentional Networks as a Function of Trait Anxiety and Depressive Symptoms: A Preregistered Double-Blind Sham-Controlled Experiment
  7. 5387
    “…Manipulation of OCM and Ca(2+) signaling may reveal important clues to the systems of function/dysfunction that lead to ARHL.…”
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    Deletion of Oncomodulin Gives Rise to Early Progressive Cochlear Dysfunction in C57 and CBA Mice
  8. 5388
    “…These results provide important clues and resources to further study the responses to low-temperature stress in bermudagrass.…”
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    A Regulatory Network of Heat Shock Modules-Photosynthesis-Redox Systems in Response to Cold Stress Across a Latitudinal Gradient in Bermudagrass
  9. 5389
    por Ray, Dhiman, Le, Ly, Andricioaei, Ioan
    Publicado 2021
    “…Also, these sites can appear in emerging mutants with possibly higher transmissibility and virulence, and preidentifying them can give clues for designing pan-coronavirus vaccines against future outbreaks. …”
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    Distant residues modulate conformational opening in SARS-CoV-2 spike protein
  10. 5390
    “…Emotional triggers of TTS were less frequent (7% vs. 19%; P=0.043), whereas physical triggers were more frequent (69% vs. 46%; P=0.005), in octogenarians/nonagenarians than in patients aged ≤79 years. As initial clues to the diagnosis, electrocardiogram changes were more frequent (71% vs. 46%; P=0.003) and chest pain and/or dyspnea were less common (25% vs. 51%; P=0.001) in octogenarians/nonagenarians than in patients aged ≤79 years. …”
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    Takotsubo Syndrome in Octogenarians and Nonagenarians
  11. 5391
    “…Extending the critical period provides new clues for the maturation of binocular vision and may have critical implications for the treatment of amblyopia.…”
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    Closing the Critical Period Is Required for the Maturation of Binocular Integration in Mouse Primary Visual Cortex
  12. 5392
    “…Constraining monsoon variability and dynamics in the warm unipolar icehouse world of the Late Oligocene can provide important clues to future climate responses to global warming. …”
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    Eccentricity-paced monsoon variability on the northeastern Tibetan Plateau in the Late Oligocene high CO(2) world
  13. 5393
    “…To detect comprehensive clues and provide more accurate forecasting in the early stage of financial distress, in addition to financial indicators, digitalization of lengthy but indispensable textual disclosure, such as Management Discussion and Analysis (MD&A), has been emphasized by researchers. …”
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    Deep Learning Based on Hierarchical Self-Attention for Finance Distress Prediction Incorporating Text
  14. 5394
    “…Assessment of the TCR repertoire of CMV-reactivated CD4+ T cells confirmed the clonal expansion of stimulated CD4+ CTL1 and CD4+ CTL2 cells, which share a large number of TCR repertoires. This study provides clues for resolving the functions of CD4+ T cell subsets and their interactions during CMV infection. …”
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    Dissecting the Landscape of Activated CMV-Stimulated CD4+ T Cells in Humans by Linking Single-Cell RNA-Seq With T-Cell Receptor Sequencing
  15. 5395
    “…The molecular mechanisms underlying prostate development can provide clues for prostate cancer research. It has been demonstrated that MEK/ERK signaling downstream of androgen-targeted FGF10 signaling directly induces prostatic branching during development, while Rho/Rho-kinase can regulate prostate cell proliferation. …”
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    Morphometric Analysis of Rat Prostate Development: Roles of MEK/ERK and Rho Signaling Pathways in Prostatic Morphogenesis
  16. 5396
    “…This work establishes crucial clues in radial glia organization, morphology and calcium signaling during development and provides insight into its role in complex behavioral paradigms.…”
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    Calcium Signaling in the Cerebellar Radial Glia and Its Association with Morphological Changes during Zebrafish Development
  17. 5397
    “…These findings should provide clues about the mechanisms of the infection, and should be useful in targeting treatments and development of vaccines. …”
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    Sex Differences in Salmonellosis Incidence Rates—An Eight-Country National Data-Pooled Analysis
  18. 5398
    “…CONCLUSION: The study concludes important clues for further research and interventions. As the nursing professionals are learning about UHP from practical exposure rather than formal teaching, it is pertinent to address this issue through well-planned formal sessions of training workshops and lecture discussions.…”
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    To Study the Awareness about Universal Health Precautions among Nursing Professionals in a Medical College Hospital of India
  19. 5399
    “…We hope that our strategies for selecting causal genes and for constructing CAPER score would provide valuable clues for guiding the management of different types of cancers.…”
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    Construction and Clinical Translation of Causal Pan-Cancer Gene Score Across Cancer Types
  20. 5400
    “…A comparison of important structural determinants for the gating mechanism between the wild type KirBac and the mutant W46R suggests interesting structural and dynamical clues and a mechanism of action of the mutation that leads to the gain of function.…”
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    Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain
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