“…Our work greatly advances the understanding of Paramyxoviridae RNA synthesis, revealing how initiation/elongation alternates, providing clues for identifying therapeutic targets against Paramyxoviridae.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These findings establish a basis for investigating the role of PPK1 in the persistence of M. tuberculosis, and provide clues for treating latent infection of M. tuberculosis with PPK1 as a potential drug target.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In conclusion, our study demonstrates that LLPS mediates ALC formation, providing essential clues for understanding the pathogenesis of deafness.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The combination of transcriptomic, proteomic, and cellular analyses would provide clues for the anti-C. albicans mechanism of TA and the defensive response mechanism of C. albicans. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This meta-analysis aimed to generate a more comprehensive understanding of the relationship between vitamin A and intramuscular fat content and to provide potential clues for future research and commercial practice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To further verify the above results, we constructed a fibroblast-like synoviocyte (FLS) cell model and administered phellodendrine for the test. All these clues suggested that SMP can significantly reduce the level of interleukin-1β (IL-1β), interleukin-6 (IL-6), and tumor necrosis factor-α (TNF-α) in complete Freund’s adjuvant rat serum and improve the degree of foot swelling; combined with metabolomics, proteomics, and network pharmacological technology, it is determined that SMP plays a therapeutic role through the inflammatory pathway, and phellodendrine is found to be one of the pharmacodynamic substances. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Delivery systems of antifungal drugs, systems based on polymers’ innate antifungal activities, and photodynamic therapies each follow their own mechanisms and unique design clues. We also discuss various prevention strategies including immunization and antifungal medical devices, and further describe point-of-care testing platforms as futuristic diagnostic and monitoring tools. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Importantly, the efficacy of anti‐CD96 and anti‐TIGIT, not inferior to anti‐PD1, in animal experiments is confirmed and targeted therapies specifically for HPV‐positive SCC, HPVA and NHPVA‐ADC, providing essential clues for further clinical trials, are proposed.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Objective: To understand the temporal trends of cancer incidence and mortality in women in Guangzhou during the past 11 years and provide clues for future research. Methods: Data were obtained from the Guangzhou Cancer and Death Registry. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…CONCLUSIONS: Pain intensity after intra-articular MIA injection increased in a dose-dependent manner and the pain trajectory manifested a specific pattern consistent with the pathological mechanisms of MIA-induced pain, providing possible clues for proper dose selection and timing of specific OA pain interventions.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…As TSPO has been suggested to have a role in heme delivery from mitochondria to the cytoplasm, the new structures provide potential clues regarding the structural basis of such activity.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These data revealed the dynamic of centromeric transcription in oocytes and its potential association with DNA repair proteins, which provide clues about how oocytes maintain centromere stability and assemble kinetochores.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The findings provide direct clues for tuning the analog resistive switching characteristics of amorphous metal oxides and developing new functions for future neuromorphic computing.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This deeper understanding of the electrolyte solvent property for SEI formation and buried interface side reactions provides beneficial clues for future Li-CO(2) battery development and electrolyte design.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study aimed to evaluate the histopathology of KC and thereby gain clues into how it forms. METHODS: The cross-sectional study cohort consisted of a convenience series of patients with keloids who underwent surgical excision. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The list of common lncRNAs identified in this study provides novel evidence and clues regarding the molecular mechanisms underlying microglial activation.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Each geophysical method applied provided different information for the reconstruction of the site: the electrical resistivity tomography offered the best clues as to the locations of the geological units and the dumps, the seismic refraction tomography visualized the transition between the dump or backfill layers and the underlying bedrock, and the IP measurements revealed residual mineralization. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The coating also drastically decreases the quenching by the molecular oxygen of the trapped charge carriers at the surfaces of the QDs. Our results provide clues to push further the emission of InP QDs into more energetically spectral regions and to increase the fluorescence quantum yield, targeting the construction of efficient UV-emissive light-emitting devices (LEDs).…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These results not only provide valuable insights into the genetic makeup of domestic ducks but also provide clues to the possible origin of domestic ducks in China. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, we found that Clostridium was enriched in CRC patients who were nonsensitive to immune checkpoint blockade (ICB) therapy. We further provided clues that the intratumor microbes might influence the response to ICB therapy by mediating TIICs, especially MAIT (mucosa-associated invariant T) cells. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso