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  1. 5641
    “…Insights into associations between HLA alleles, lung immune cells, clinical phenotype including extra pulmonary manifestations (EPM), and PB lymphopenia may provide mechanistic clues and enable adequate intervention in this patient group. …”
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    Peripheral blood lymphopenia in sarcoidosis associates with HLA-DRB1 alleles but not with lung immune cells and organ involvement
  2. 5642
    “…Our study clarifies the molecular mechanisms of neuritin in regulating the Notch signaling pathway and provides new clues about how neuritin mediates neural regeneration and plasticity.…”
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    Neuritin affects the activity of neuralized-like 1 by promoting degradation and weakening its affinity for substrate: Neuritin regulates the activity of the E3 ligase NEURL1
  3. 5643
    “…These results provide clues on the role of the p53-DREAM pathway in regulating hematopoiesis and brain development, with implications for tumorigenesis.…”
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    A systematic approach identifies p53-DREAM pathway target genes associated with blood or brain abnormalities
  4. 5644
    “…These results provide clues from a bioinformatic perspective and highlight the importance of NCS1 in a variety of cancers.…”
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    The Role of NCS1 in Immunotherapy and Prognosis of Human Cancer
  5. 5645
    por Yasmin, O’Shaughnessy, Kevin M.
    Publicado 2023
    “…Genome-wide scans performed in affected sib pairs have revealed small and often inconsistent clues to the loci responsible for the inherited components of hypertension. …”
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    Genetic Markers Regulating Blood Pressure in Extreme Discordant Sib Pairs
  6. 5646
    “…Thus, this study provides important clues for future studies on enhancing antibiotic production in Streptomyces systems.…”
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    Multicopy Chromosome Integration and Deletion of Negative Global Regulators Significantly Increased the Heterologous Production of Aborycin in Streptomyces coelicolor
  7. 5647
    “…This finding provides new clues and directions for exploring the mechanism of the impact of DTIW on muscle function and health and also provides new evidence and suggestions for adults to adjust their water intake reasonably.…”
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    Water Intake and Handgrip Strength in US Adults: A Cross-Sectional Study Based on NHANES 2011–2014 Data
  8. 5648
    “…These findings reveal the association of AACE and the visual center, giving us more clues about the treatment of AACE.…”
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    Deficits of Visual Cortex Function in Acute Acquired Concomitant Esotropia Patients
  9. 5649
    “…CLINICAL DISCUSSION: Important clinical clues were provided for distinguishing between choroidal melanoma and haemorrhagic CD in cases of coexisting RRD. …”
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    Coexistence of choroidal melanoma and rhegmatogenous retinal detachment: a case report and literature review
  10. 5650
    “…Our investigation of elasmobranch karyotypes underpins their unique characteristics and provides clues for understanding how vertebrate karyotypes accommodate intragenomic heterogeneity to realize a complex readout. …”
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    Elasmobranch genome sequencing reveals evolutionary trends of vertebrate karyotype organization
  11. 5651
    por Zuo, Huifang, Li, Min-Min
    Publicado 2023
    “…Furthermore, it may provide new clues for risk management and preventive interventions for mental disorders in patients with AS.…”
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    Ankylosing spondylitis and psychiatric disorders in European population: a Mendelian randomization study
  12. 5652
    “…These results suggest that MAP70 confines microtubules within the pit apertures by altering the physical properties of microtubules, thereby directing the growth of pit arches in the proper orientation. This study provides clues to understanding how plants develop three-dimensional structure of cell walls.…”
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    Confined-microtubule assembly shapes three-dimensional cell wall structures in xylem vessels
  13. 5653
    “…This short review questions current thinking on drug action and looks at whether adopting the philosophy of ex-US Secretary of State Donald Rumsfeld reveals ‘unknown’ aspects of the actions of levodopa and apomorphine that provide clues for a way forward. It appears that both levodopa and apomorphine have a more complex pharmacology than classical views would suggest. …”
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    Adopting the Rumsfeld approach to understanding the action of levodopa and apomorphine in Parkinson’s disease
  14. 5654
    “…This study reveals the importance of EGFR in the regulation of NHE3 activity by PEDV and provides new targets and clues for the prevention and treatment of PEDV-induced diarrhea in piglets.…”
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    Porcine epidemic diarrhea virus causes diarrhea by activating EGFR to regulates NHE3 activity and mobility on plasma membrane
  15. 5655
    “…In this paper, through our experience and a literature analysis, we will aim to outline some clues to identify patients at potential risk of bilateral adrenal hemorrhage.…”
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    Bilateral adrenal hemorrhage: learning notes from clinical practice and literature review
  16. 5656
    “…The expanding list of aberrantly spliced genes in IBD along with the developed technologies provide us new clues to how IBD develops, and how these important AS events can be explored for future treatment.…”
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    Crosstalk between alternative splicing and inflammatory bowel disease: Basic mechanisms, biotechnological progresses and future perspectives
  17. 5657
    “…These findings provide valuable clues on the differential surface fouling intensity of Fucus spp., and their importance in marine chemical defense and fouling dynamics.…”
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    Metabolomics and Microbiomics Insights into Differential Surface Fouling of Three Macroalgal Species of Fucus (Fucales, Phaeophyceae) That Co-Exist in the German Baltic Sea
  18. 5658
    “…Analysis of cis-regulatory regions for the genes of interest revealed clues to upstream regulation of these pathways.…”
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    Dishevelled Has Anti-Viral Activity in Rift Valley Fever Virus Infected Aedes aegypti
  19. 5659
    “…Our results provide new insights into the control of ligamental degeneration and potential clues to developing novel diagnostic and therapeutic strategies. …”
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    A single-cell atlas depicting the cellular and molecular features in human anterior cruciate ligamental degeneration: A single cell combined spatial transcriptomics study
  20. 5660
    por Wu, Yingzi, Luo, Jinhai, Xu, Baojun
    Publicado 2023
    “…CONCLUSION: This study provides clues for further study of anti-CRC phytochemicals as well as their mechanisms of provides a basis for their development model.…”
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    Network pharmacology and bioinformatics to identify the molecular mechanisms of Gleditsiae Spina against colorectal cancer
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