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5801por Chege, Duncan, Chai, Yijie, Huibner, Sanja, Kain, Taylor, Wachihi, Charles, Kimani, Makubo, Barasa, Samson, McKinnon, Lyle R., Muriuki, Festus K., Kariri, Anthony, Jaoko, Walter, Anzala, Omu, Kimani, Joshua, Ball, T. Blake, Plummer, Francis A., Kaul, Rupert“…BACKGROUND: Identifying the immune correlates of reduced susceptibility to HIV remains a key goal for the HIV vaccine field, and individuals who are HIV-exposed, seronegative (HESN) may offer important clues. Reduced systemic immune activation has been described in HESN individuals. …”
Publicado 2012
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5802Gene Network and Pathway Analysis of Mice with Conditional Ablation of Dicer in Post-Mitotic Neuronspor Dorval, Véronique, Smith, Pascal Y., Delay, Charlotte, Calvo, Ezequiel, Planel, Emmanuel, Zommer, Nadège, Buée, Luc, Hébert, Sébastien S.“…CONCLUSIONS/SIGNIFICANCE: Taken together, these results provide new clues into the role of specific miRNA pathways in the regulation of brain identity and maintenance in adult mice.…”
Publicado 2012
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5803“…We hope that IDEN 2012, as the very prestigious endoscopy networks, served as an opportunity to gain some clues for further understanding of endoscopic technologies and to enhance up-and-coming knowledge and their clinical implications from selected 25 peer reviewed articles and 112 invited lectures.…”
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5804por Carswell, Christopher, Rañopa, Michael, Pal, Suvankar, MacFarlane, Rebecca, Siddique, Durre, Thomas, Dafydd, Webb, Tom, Wroe, Steve, Walker, Sarah, Darbyshire, Janet, Collinge, John, Mead, Simon, Rudge, Peter“…Highly visual neurological examination domains (e.g. finger-nose-finger assessment of ataxia) had good inter-rater correlation, whereas those dependent on non-visual clues (e.g. power or reflexes) correlated poorly. …”
Publicado 2012
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5805“…Furthermore, we show which amino acids at which position are important for prediction success, giving clues on how the interaction mechanism between the V3 loop and the particular coreceptors might be influenced. …”
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5806por Janssen, Sarah F., Gorgels, Theo G. M. F., Bossers, Koen, ten Brink, Jacoline B., Essing, Anke H. W., Nagtegaal, Martijn, van der Spek, Peter J., Jansonius, Nomdo M., Bergen, Arthur A. B.“…We also developed molecular signatures for the NPE and PE and studied possible new clues for glaucoma. METHODS: We isolated NPE and PE cells from seven healthy human donor eyes using laser dissection microscopy. …”
Publicado 2012
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5807“…Differences in prevalence of exposure, PTSD and demographic variables between ethnicities may reveal some important clues to the etiology of the disease. The present study replicated six previous non-clinical studies which were designed to provide epidemiological information about exposure to PTEs, and the prevalence of PTSD among adolescents (see Table 1). …”
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5808“…The molecular survey of HCV provides some clues about the epidemiological status of the infections in a local scale and the phylogenetic and demographic reconstruction analyses complement this study by inferring whether the infections of certain subtypes are in a steady state or expanding. …”
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5809“…Its complete sequence of the mitochondrial (mt) genome could provide clues for the understanding of the evolution of mt genomes in plant. …”
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5810por Maekawa, Tatsunori, Mori, Sayuri, Sasaki, Yui, Miyajima, Takashi, Azuma, Sadahiro, Ohta, Etsuro, Obata, Fumiya“…The TG mouse should provide valuable clues to the etiology of PD caused by the LRRK2 mutation.…”
Publicado 2012
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5811por Jin, Fengyan, Ji, Huifan, Jia, Chunshu, Brockmeier, Ulf, Hermann, Dirk M., Metzen, Eric, Zhu, Yingqiao, Chi, Baorong“…Our data not only provide clues to aid understanding of the mechanism of the synergism of endostar and chemotherapy under either normoxia or hypoxia, but also suggests a new strategy of combination endostar and chemotherapy treatments which might potentiate therapeutic efficacies and/or counteract chemotherapy resistance.…”
Publicado 2012
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5812por Wang, Rui, Wang, Hong-Bin, Hao, Chan Juan, Cui, Yi, Han, Xiao-Chen, Hu, Yi, Li, Fei-Feng, Xia, Hong-Fei, Ma, Xu“…CONCLUSIONS: This study demonstrates that down-regulation of miR-101 in different subtypes of human breast cancer tissues is linked to the increase of cellular proliferation and invasiveness via targeting Stmn1, which highlights novel regulatory mechanism in breast cancer and may provide valuable clues for the future clinical diagnosis of breast cancer.…”
Publicado 2012
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5813por Parker, Robert, Guarna, M Marta, Melathopoulos, Andony P, Moon, Kyung-Mee, White, Rick, Huxter, Elizabeth, Pernal, Stephen F, Foster, Leonard J“…The most important biochemical correlations provide clues as to the underlying molecular mechanisms of social and innate immunity of honey bees. …”
Publicado 2012
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5814por Loor Solorzano, Rey Gaston, Fouet, Olivier, Lemainque, Arnaud, Pavek, Sylvana, Boccara, Michel, Argout, Xavier, Amores, Freddy, Courtois, Brigitte, Risterucci, Ange Marie, Lanaud, Claire“…As large unexplored forest areas still exist in the southern part of the Ecuadorian Amazonian region, our findings could provide clues as to where precious new genetic resources could be collected, and subsequently used to improve the flavour and disease resistance of modern Ecuadorian cocoa varieties.…”
Publicado 2012
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5815por Li, Bohui, Xu, Xue, Wang, Xia, Yu, Hua, Li, Xiuxiu, Tao, Weiyang, Wang, Yonghua, Yang, Ling“…This means that for the first time, the action mechanism of these three important Chinese herbs for the treatment of CVD is uncovered, by generating and identifying both their active ingredients and novel targets specifically related to CVD, which clarifies some of the common conceptions in TCM, and thus provides clues to modernize such specific herbal medicines.…”
Publicado 2012
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5816“…Analysis of the far-field diffraction patterns reveals clues about the waveforms of the nematodes. Diffraction is the process of light bending around an object. …”
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5817por Ray, Debalina, Nelson, Tyrrell A., Fu, Chi-Ling, Patel, Shailja, Gong, Diana N., Odegaard, Justin I., Hsieh, Michael H.“…Taken together, our findings have important implications for understanding host-parasite interactions and carcinogenesis in urogenital schistosomiasis, and may provide clues for novel therapeutic strategies.…”
Publicado 2012
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5818por Salawu, Abdulazeez, Ul-Hassan, Aliya, Hammond, David, Fernando, Malee, Reed, Malcolm, Sisley, Karen“…These results suggest that archival FFPE tissue, with its relative abundance and attendant clinical data may be used for effective mapping for genomic copy number aberrations in such rare tumours as leiomyosarcoma and potentially unravel clues to tumour origins, progression and ultimately, targeted treatment.…”
Publicado 2012
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5819“…The study of families with multiple affected children can provide clues about ASD etiology. While the majority of research on ASD multiplex families has focused on identifying genetic anomalies that may underlie the disorder, the study of symptom severity across ASD birth order may provide evidence for environmental factors in ASD. …”
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5820“…A comprehensive approach will often provide clues for a presumptive diagnosis and appropriate management. …”
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