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  1. 5821
    por DeParis, SW, Caprara, C, Grimm, C
    Publicado 2012
    “…Identification of the responsible molecular survival mechanisms may provide clues to protect “traditional” ganglion cells in diseases such as glaucoma.…”
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    Intrinsically photosensitive retinal ganglion cells are resistant to N-methyl-D-aspartic acid excitotoxicity
  2. 5822
    “…Specifically, identification of similar and frequently occurring patterns (network motifs) across PPI networks will provide useful clues to better understand the biology of the diseases. …”
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    Mining functional subgraphs from cancer protein-protein interaction networks
  3. 5823
    por Lindström, Mikael S.
    Publicado 2012
    “…Identification of amino acid sequences mediating nucleolar localization of ribosomal proteins may provide important clues to understand the early steps in ribosome biogenesis. …”
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    Elucidation of Motifs in Ribosomal Protein S9 That Mediate Its Nucleolar Localization and Binding to NPM1/Nucleophosmin
  4. 5824
    por Qiu, Xiaojie, Ding, Shanshan, Shi, Tieliu
    Publicado 2012
    “…Our work provides new insights into cellular differentiation and important clues for better reprogramming strategies.…”
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    From Understanding the Development Landscape of the Canonical Fate-Switch Pair to Constructing a Dynamic Landscape for Two-Step Neural Differentiation
  5. 5825
    “…Comparative genome analysis of non-avian reptiles and amphibians provides important clues about the process of genome evolution in tetrapods. …”
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    Inference of the Protokaryotypes of Amniotes and Tetrapods and the Evolutionary Processes of Microchromosomes from Comparative Gene Mapping
  6. 5826
    por Yu, Dan, Zhao, Liping, Xue, Ting, Sun, Baolin
    Publicado 2012
    “…This study may provide clues for therapy in S. aureus biofilm-associated infection.…”
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    Staphylococcus aureus autoinducer-2 quorum sensing decreases biofilm formation in an icaR-dependent manner
  7. 5827
    “…CONCLUSIONS/SIGNIFICANCE: To our knowledge this is the first study to elucidate the genetic makeup of Macleaya spp. This work provides clues to the identification of the potential modulate genes involved in alkaloids biosynthesis in Macleaya spp., and sheds light on researches for non-model medicinal plants by integrating different high-throughput technologies.…”
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    Integration of Transcriptome, Proteome and Metabolism Data Reveals the Alkaloids Biosynthesis in Macleaya cordata and Macleaya microcarpa
  8. 5828
    por Zhang, Weiwei, Li, Zhenzhong
    Publicado 2013
    “…These results not only provide new clues for a better understanding of the association of SKM cells with DRG sensory neurons during development, they may also have implications for axonal regeneration after nerve injury.…”
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    The Effects of Target Skeletal Muscle Cells on Dorsal Root Ganglion Neuronal Outgrowth and Migration In Vitro
  9. 5829
    “…Analyses such as this, combining evolutionary theory and predictions - along with medically relevant data, can thus provide us with important clues for modeling human diseases.…”
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    Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions
  10. 5830
    “…These findings and the structural elucidation might give some clues in aspects of developing highly specific G-quadruplex probes.…”
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    A dual-site simultaneous binding mode in the interaction between parallel-stranded G-quadruplex [d(TGGGGT)](4) and cyanine dye 2,2′-diethyl-9-methyl-selenacarbocyanine bromide
  11. 5831
    “…We analyzed the evolution and expression of the TCP gene family in vetch at a whole-genome level, and several unigenes specific to three different vetch petals, which might offer some clues toward elucidating the molecular mechanisms underlying floral zygomorphy. …”
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    Comparative Transcriptional Profiling Provides Insights into the Evolution and Development of the Zygomorphic Flower of Vicia sativa (Papilionoideae)
  12. 5832
    “…Our studies provide information of the S. exigua Topo1 gene and its amino acid polymorphism in insects and uncover some clues about potential mechanisms of CPT toxicity against insect pests. …”
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    Characterization of DNA Topoisomerase-1 in Spodoptera exigua for Toxicity Evaluation of Camptothecin and Hydoxy-Camptothecin
  13. 5833
    “…. • To learn about some clues that help differentiate the various diagnostic mimics on HRCT.…”
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    Mimics in chest disease: interstitial opacities
  14. 5834
    “…History of PPH, lactational failure and cessation of menses are important clues. Thyrotroph, corticotroph axis may be preserved in some SS patients.…”
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    Varied presentations of Sheehan's syndrome at diagnosis: A review of 18 patients
  15. 5835
    “…Hence, the annotation and interpretation of this sequence provides a vast array of clues into the genomic underpinnings of the physiology of this cyanobacterium and indicates in particular a competitive edge of N. spumigena in nutrient-limited brackish water ecosystems.…”
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    Insights into the Physiology and Ecology of the Brackish-Water-Adapted Cyanobacterium Nodularia spumigena CCY9414 Based on a Genome-Transcriptome Analysis
  16. 5836
    “…Additionally, MMP-9 plays an important role in maintaining IOP, and further investigation into the mechanisms of MMP-9 activity in the anterior angle may give clues to how extracellular matrix remodeling participates in ocular hypertension and glaucoma.…”
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    Altered expression of transforming growth factor beta 1 and matrix metalloproteinase-9 results in elevated intraocular pressure in mice
  17. 5837
    “…These results significantly unveil the structure and evolution of the Hippo pathway in distant phyla and provide valuable clues for further examination of Hippo signaling.…”
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    Hippo pathway genes developed varied exon numbers and coevolved functional domains in metazoans for species specific growth control
  18. 5838
    “…These results provide a possible mechanism for an age related hearing loss sub-type that is associated with gender and provides clues as to how this gender bias in hearing loss develops. …”
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    Prolactin Expression in the Cochlea of Aged BALB/c Mice Is Gender Biased and Correlates to Loss of Bone Mineral Density and Hearing Loss
  19. 5839
    “…To find clues about the mechanism by which kinase C epsilon (PKCε) may impart susceptibility to ultraviolet radiation (UVR)-induced development of cutaneous squamous cell carcinomas (SCC), we compared PKCε transgenic (TG) mice and their wild-type (WT) littermates for (1) the effects of UVR exposures on percent of putative hair follicle stem cells (HSCs) and (2) HSCs proliferation. …”
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    Protein Kinase Cε, Which Is Linked to Ultraviolet Radiation-Induced Development of Squamous Cell Carcinomas, Stimulates Rapid Turnover of Adult Hair Follicle Stem Cells
  20. 5840
    “…These results provide new clues to improve conservation measures within urbanised areas in favour of specialist flower-visitors. …”
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    Plant Pollinator Networks along a Gradient of Urbanisation
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