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  1. 5941
    “…Although many questions regarding the immune responses remain unanswered, these findings provide insight and clues that may help reduce the impact of PRRSv in pregnant gilts.…”
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    Changes in leukocyte subsets of pregnant gilts experimentally infected with porcine reproductive and respiratory syndrome virus and relationships with viral load and fetal outcome
  2. 5942
    “…In conclusion, our data demonstrate an ITC-induced mechanism leading to growth inhibition in A. thaliana and rat bladder cancer cells, and expose clues to the mechanisms underlying the physiological role of glucosinolates in vivo.…”
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    Disintegration of microtubules in Arabidopsis thaliana and bladder cancer cells by isothiocyanates
  3. 5943
    “…BACKGROUND: Psychogenic or functional movement disorders (PMDs) pose a challenge in clinical diagnosis. There are several clues, including sudden onset, incongruous symptoms, distractibility, suggestibility, entrainment of symptoms, and lack of response to otherwise effective pharmacological therapies, that help identify the most common psychogenic movements such as tremor, dystonia, and myoclonus. …”
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    Recognizing Uncommon Presentations of Psychogenic (Functional) Movement Disorders
  4. 5944
    “…Furthermore, abundances of nitrogen cycle and phosphorus cycle genes were concomitant with NH(4)(+)-N, NO(3)(−)-N and total phosphorus, offering tangible clues to the underlying mechanisms of soil biogeochemical cycles. …”
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    Integrated metagenomics and network analysis of soil microbial community of the forest timberline
  5. 5945
    por Maeda, Kazuhiro, Kurata, Hiroyuki
    Publicado 2014
    “…The analytical solutions give synthetic biologists some clues to design gene oscillators with robust and desired period.…”
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    Analytical study of robustness of a negative feedback oscillator by multiparameter sensitivity
  6. 5946
    “…Although SRH is an important study topic providing clues to enhance a person’s quality of life, there is currently insufficient data on age- and gender-specific differences among factors associated with SRH in Japan, particularly in rural areas. …”
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    Factors Associated with Self-rated Health in the Rural Population: Age- and Gender-specific Analysis
  7. 5947
    “…Systematic identification of these keto acids transporters would provide clues to further improve the accumulation of specific organic acids with higher efficiency in eukaryotic microorganisms.…”
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    Identification and application of keto acids transporters in Yarrowia lipolytica
  8. 5948
    “…Moreover, the mild down regulation of membranous β-catenin expression in non lesional psoriatic skin may provide clues about incipient structural abnormalities in the pathogenesis of psoriasis, providing an early diagnostic indicator for evolution to a generalized form of the disease. …”
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    Beta-catenin expression in psoriasis
  9. 5949
    “…In the study, we investigated spatio-temporal variations of S. japonicum infection risk in Anhui Province and assessed the associations of the disease with key environmental factors with the aim of understanding the mechanism of the disease and seeking clues to effective and sustainable schistosomiasis control. …”
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    Spatio-temporal Transmission and Environmental Determinants of Schistosomiasis Japonica in Anhui Province, China
  10. 5950
    “…Further studies are needed to identify its mechanism of action and more clues into its structure-activity relationship.…”
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    Anticonvulsant Effect of Cicer arietinum Seed in Animal Models of Epilepsy: Introduction of an Active Molecule with Novel Chemical Structure
  11. 5951
    “…Clues to Alzheimer disease (AD) pathogenesis come from a variety of different sources including studies of clinical and neuropathological features, biomarkers, genomics and animal and cellular models. …”
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    A γ-Secretase Inhibitor, but Not a γ-Secretase Modulator, Induced Defects in BDNF Axonal Trafficking and Signaling: Evidence for a Role for APP
  12. 5952
    “…This work has begun to yield new insights into fundamental questions about the nature of the mind and important clues about the origins of mental illness. In particular, this research demonstrates that stress, anxiety, and other kinds of emotion can profoundly influence key elements of cognition, including selective attention, working memory, and cognitive control. …”
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    The neurobiology of emotion–cognition interactions: fundamental questions and strategies for future research
  13. 5953
    “…The results of the study provide new hormone-related clues to define the genetic network that governs SE. …”
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    ERF022 impacts the induction of somatic embryogenesis in Arabidopsis through the ethylene-related pathway
  14. 5954
    “…The results will not only enhance our current understanding of the genetic basis of RP, but also provide helpful clues for designing future studies to further investigate genetic factors for familial RP.…”
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    Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa
  15. 5955
    “…In this case, previous animal contact and conjunctival samples showing Enterobacteriaceae like colonies with positive oxidase test were two important clues which could help clinicians to make the diagnosis of Pasteurella conjunctivitis in every day practice.…”
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    Rapidly evolving conjunctivitis due to Pasteurella multocida, occurring after direct inoculation with animal droplets in an immuno-compromised host
  16. 5956
    “…This work revealed that the steric, hydrophobic, and H-bond factors should appropriately be taken into account in future rational design, especially the modifications at the 2′-position of the benzene and the 6-position of the benzothiophene in the R group, providing helpful clues to design more active and selective FIXa inhibitors for the treatment of thrombosis. …”
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    Design and prediction of new anticoagulants as a selective Factor IXa inhibitor via three-dimensional quantitative structure-property relationships of amidinobenzothiophene derivatives
  17. 5957
    “…In summary, ADReCS offers an opportunity for direct computation on ADR terms and also provides clues to mining common features underlying ADRs.…”
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    ADReCS: an ontology database for aiding standardization and hierarchical classification of adverse drug reaction terms
  18. 5958
    “…The relative animal studies provide important clues to design pre-clinical studies and clinical studies further in the future. …”
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    Stem Cell Therapy for Erectile Dysfunction of Cavernous Nerve Injury Rats: A Systematic Review and Meta-Analysis
  19. 5959
    “…CONCLUSIONS: We defined GFxF (α3142, 143,145) as the critical motif of P14. It may provide some clues for understanding the etiology of anti-GBM disease.…”
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    Identification of Critical Residues of Linear B Cell Epitope on Goodpasture Autoantigen
  20. 5960
    “…Hence, computational analysis of constituent proteins could provide important clues to the functional relationships within the operonic genes. …”
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    Rv2031c of Mycobacterium tuberculosis: a master regulator of Rv2028–Rv2031 (HspX) operon
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