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6141por Li, L., Zheng, Q., Zou, Q., Rajput, S., Ijaduola, A. O., Wu, Z., Wang, X. P., Cao, H. B., Somnath, S., Jesse, S., Chi, M., Gai, Z., Parker, D., Sefat, A. S.“…Although there are some clues for designing such materials, they remain mainly unpredictable. …”
Publicado 2017
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6142por Iaconis, Daniela, Monti, Maria, Renda, Mario, van Koppen, Arianne, Tammaro, Roberta, Chiaravalli, Marco, Cozzolino, Flora, Pignata, Paola, Crina, Claudia, Pucci, Piero, Boletta, Alessandra, Belcastro, Vincenzo, Giles, Rachel H., Surace, Enrico Maria, Gallo, Simone, Pende, Mario, Franco, Brunella“…Our results suggest a possible role for the centrosome as a specialized station to modulate translation for specific functions of the nearby ciliary structures and may provide functional clues for the understanding of renal cystic disease.…”
Publicado 2017
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6143“…In clinical decision making, in addition to anatomical information, biomechanical properties of soft tissues may provide additional clues for disease diagnosis. Given the fact that most of diseases are originated from micron sized structures, an elastography imaging system of fine resolution (~100 µm) and deep penetration depth capable of providing both qualitative and quantitative measurements of biomechanical properties is desired. …”
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6144por Modica, Teresa Maria Elisa, Maiorani, Orlando, Sartori, Giulio, Pivetta, Eliana, Doliana, Roberto, Capuano, Alessandra, Colombatti, Alfonso, Spessotto, Paola“…It exerts its function through a signal cascade starting from the integrins that take direct contact with matrix constituents most of which behave as pro-proliferative clues. On the contrary, EMILIN1, a glycoprotein interacting with the α4β1 integrin through its gC1q domain, plays a paradigmatic anti-proliferative role. …”
Publicado 2017
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6145“…The study data provide clues regarding underlying mechanisms associated with AVP for future physiological researches on AVP. …”
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6146“…This study greatly expands the number of genetic variants that may contribute to JIA and give us some clues into what may trigger this disease. To date, this study is the first deep WGS effort on children with JIA and provides useful genetic resources for research communities particularly in understanding JIA etiology.…”
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6147por Lai, Wei-Yun, Chen, Yi-Wen, Kao, Chia-Tze, Hsu, Tuan-Ti, Huang, Tsui-Hsien, Shie, Ming-You“…This study provides new and important clues regarding the major effects of Si-induced cell behavior as well as the precipitated apatite-inhibited hDPC behavior on these materials.…”
Publicado 2015
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6148“…Our prospective findings provide a first set of clues in favor of the occurrence of an overshadowing between visual cues during a spatial learning task in mice when both types of cues are of the same modality but at varying distances from the goal. …”
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6149Structural Modeling of Chromatin Integrates Genome Features and Reveals Chromosome Folding Principle“…Taken together, these results provide clues to the folding principles of chromosomes, their spatial organization, and the resulted clustering of many genome features in the 3D space.…”
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6150por Klemann, C. J. H. M., Martens, G. J. M., Sharma, M., Martens, M. B., Isacson, O., Gasser, T., Visser, J. E., Poelmans, G.“…Taken together, our findings provide novel insights into the molecular pathways underlying the etiology of (sporadic) Parkinson’s disease and highlight a key role for lipids and lipoproteins in Parkinson’s disease pathogenesis, providing important clues for the development of disease-modifying treatments of Parkinson’s disease.…”
Publicado 2017
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6151por Cosentino, Giuseppe, Valentino, Francesca, Todisco, Massimiliano, Alfonsi, Enrico, Davì, Rosaria, Savettieri, Giovanni, Fierro, Brigida, D’Amelio, Marco, Brighina, Filippo“…Conclusion: Our findings support the potential usefulness of tDCS as add-on treatment for asymmetric PD, also providing interesting clues on the possible pathophysiological role played by an asymmetric activation of homologous motor cortical areas in PD.…”
Publicado 2017
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6152“…These observations are propitious to expand our understanding of protein structure and function as well as providing clues for performing structure-based drug design.…”
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6153por Duwaerts, Caroline C., Amin, Amin M., Siao, Kevin, Her, Chris, Fitch, Mark, Beysen, Carine, Turner, Scott M., Goodsell, Amanda, Baron, Jody L., Grenert, James P., Cho, Soo-Jin, Maher, Jacquelyn J.“…Starch-oleate phenocopies the effect of a Western diet; consequently, it may provide clues to the mechanism whereby specific nutrients cause metabolically unhealthy obesity.…”
Publicado 2017
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6154por Masini, Matilde, Marselli, Lorella, Himpe, Eddy, Martino, Luisa, Bugliani, Marco, Suleiman, Mara, Boggi, Ugo, Filipponi, Franco, Occhipinti, Margherita, Bouwens, Luc, De Tata, Vincenzo, Marchetti, Piero“…To search for clues suggesting that beta cells may generate by transdifferentiation in humans, we assessed the presence of cells double positive for exocrine (amylase, carboxypeptidase A) and endocrine (insulin) markers in the pancreas of non-diabetic individuals (ND) and patients with type 2 diabetes (T2D). …”
Publicado 2017
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6155“…Our current data provides important clues for studying the mechanisms involved in Cr (VI)-induced liver injury, and may be of great help to develop therapeutic strategies for prevention and treatment of liver diseases involving ROS accumulation for occupational exposure population.…”
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6156por Ramasubramanian, Chellamuthu, Mohandoss, Anusa Arunachalam, Namasivayam, Rajesh Kannan“…CONCLUSION: Understanding the interplay of factors may yield robust estimates and clues for policy framers to formulate employment-related policies for employment opportunities for mentally ill patients.…”
Publicado 2016
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6157“…These results provide some clues for future studies on the role of DSCAM overexpression in the precocious cognitive decline observed in APP transgenic mice.…”
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6158“…Therefore, myogenic studies on sharks are essential in yielding clues on the developmental processes involved in the origin of the muscular anatomy. …”
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6159por Nalinratana, Nonthaneth, Kaewprem, Weeraya, Tongumpai, Sarunya, Luechapudiporn, Rataya, Sotanaphun, Uthai, Meksuriyen, Duangdeun“…CONCLUSION: Our findings demonstrate that the synergistic antioxidant action of PN ameliorates endothelial stress, which may provide some clues for understanding the traditional use of PN for the treatment of circulatory disorder. …”
Publicado 2014
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6160“…Therefore, identifying changes in gene expression pattern in the peritoneal fibroblasts during the process may provide clues to the mechanisms by which adhesion develop. …”
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