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6301por Ekdahl, Anja, Weidolf, Lars, Baginski, Matthew, Morikawa, Yoshio, Thompson, Richard A., Wilson, Ian D.“…The different pattern of metabolism seen in these chimeric mice with a humanized liver compared to the conventional rodents may offer clues to the factors that contributed to the drug-induced liver injury seen in humans. …”
Publicado 2018
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6302por Anand, Akshay, Goyal, Atul Kumar, Bakshi, Jaimanti, Sharma, Kaushal, Vir, Dharam, Didi, Anita“…Therefore, the present article not only reviews the current status of research studies in oral cancer, obesity, and neurodegenerative disorders but also how these are linked to each other and why the investigations of the putative NGF pathway, involving TNF-α and IL-6, could provide useful clues to understand the molecular effects brought about by yoga intervention in such patients.…”
Publicado 2018
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6303por Ali, Nouman, Zafar, Bushra, Riaz, Faisal, Hanif Dar, Saadat, Iqbal Ratyal, Naeem, Bashir Bajwa, Khalid, Kashif Iqbal, Muhammad, Sajid, Muhammad“…Among these, the division of image-space into different geometric sub-regions for the extraction of histogram for BoF model is considered as a notable contribution for the extraction of spatial clues. Keeping this in view, we aim to explore a Hybrid Geometric Spatial Image Representation (HGSIR) that is based on the combination of histograms computed over the rectangular, triangular and circular regions of the image. …”
Publicado 2018
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6304“…These results of human perception and eye fixation provide important clues for understanding the visual processing for FG segregation.…”
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6305“…Accurate identification of anti-angiogenic peptides may provide significant clues to understand the essential angiogenic homeostasis within tissues and develop antineoplastic therapies. …”
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6306por Shi, Qianqian, Li, Long, Zhang, Xiaoxiao, Luo, Jianrang, Li, Xiang, Zhai, Lijuan, He, Lixia, Zhang, Yanlong“…Our results indicated that the various variegation patterns were caused by transcriptional regulation of anthocyanin biosynthesis genes, and the transcription profiles of the R2R3-MYBs provided clues to elucidate the mechanisms underlying this trait. …”
Publicado 2017
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6307por Terekhov, Stanislav S., Smirnov, Ivan V., Malakhova, Maja V., Samoilov, Andrei E., Manolov, Alexander I., Nazarov, Anton S., Danilov, Dmitry V., Dubiley, Svetlana A., Osterman, Ilya A., Rubtsova, Maria P., Kostryukova, Elena S., Ziganshin, Rustam H., Kornienko, Maria A., Vanyushkina, Anna A., Bukato, Olga N., Ilina, Elena N., Vlasov, Valentin V., Severinov, Konstantin V., Gabibov, Alexander G., Altman, Sidney“…Microbiome spectra serve as critical clues to elucidate the evolutionary biology pathways, potential pathologies, and even behavioral patterns of the host organisms. …”
Publicado 2018
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6308por Kiyohara, Kosuke, Nishiyama, Chika, Kiguchi, Takeyuki, Kobayashi, Daisuke, Iwami, Taku, Kitamura, Tetsuhisa“…These traits provide useful clues for the prevention of OHCAs and the improvement of prehospital care for these patients. …”
Publicado 2018
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6309por Brajic, Aleksandra, Franckaert, Dean, Burton, Oliver, Bornschein, Simon, Calvanese, Anna L., Demeyer, Sofie, Cools, Jan, Dooley, James, Schlenner, Susan, Liston, Adrian“…These results implicate Flatr as part of the upstream cascade leading to Treg conversion, and may provide clues as to the nature of this process.…”
Publicado 2018
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6310por Ács-Szabó, Lajos, Papp, László Attila, Antunovics, Zsuzsa, Sipiczki, Matthias, Miklós, Ida“…The fission yeast clade, which has a distinct life history from other yeasts, can provide important clues about evolutionary changes. To reveal these changes the large S. cryophilus supercontigs were assembled into chromosomes using synteny relationships and the conserved pericentromeric, subtelomeric genes. …”
Publicado 2018
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6311por Condorelli, Daniele F., Spampinato, Giorgia, Valenti, Giovanna, Musso, Nicolò, Castorina, Sergio, Barresi, Vincenza“…We show that cancer-upregulated transcripts are sensitive markers of BCNA-induced effects and suggest that analysis of positive caricature transcriptomic effects can provide clues toward the identification of BCNA-associated cancer driver genes.…”
Publicado 2018
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6312por Yuan, Hongjun, Zeng, Xingquan, Yang, Qiaofeng, Xu, Qijun, Wang, Yulin, Jabu, Dunzhu, Sang, Zha, Tashi, Nyima“…These findings greatly improve our understanding of the mechanisms of induced defense response in Qingke and will provide new clues for the development of resistant Tibetan hulless barley varieties.…”
Publicado 2018
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6313“…CONCLUSIONS: Here, we provide clues for the antagonism of Escovopsioides towards the mutualistic fungus of leafcutter ants. …”
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6314por Winnike, Jason H., Stewart, Delisha A., Pathmasiri, Wimal W., McRitchie, Susan L., Sumner, Susan J.“…Overall, cell lines that have different hormone receptor status have different energy utilization requirements, even if they are classified by the same clinical BCa subtype; and these differences offer clues about optimizing treatment strategies.…”
Publicado 2018
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6315por Serrano, J. Ignacio, del Castillo, María Dolores, Cortés, Verónica, Mendes, Nuno, Arroyo, Aida, Andreo, Jorge, Rocon, Eduardo, del Valle, María, Herreros, Jaime, Romero, Juan Pablo“…Objectives: Characterizing pharmacological response in Parkinson’s Disease (PD) patients may be a challenge in early stages but gives valuable clues for diagnosis. Neurotropic drugs may modulate Electroencephalography (EEG) microstates (MS). …”
Publicado 2018
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6316“…The results suggest fatal metabolic alterations correlated with SCD events during acute MI, which could offer novel clues for the prevention or treatment of acute MI-related SCD.…”
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6317“…CONCLUSIONS: Preoperative strong clues for bucket handle tears of the medial meniscus in stable knees are male gender, locking events and limitation in extension. …”
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6318por Luo, Fengtao, Xie, Yangli, Wang, Zuqiang, Huang, Junlan, Tan, Qiaoyan, Sun, Xianding, Li, Fangfang, Li, Can, Liu, Mi, Zhang, Dali, Xu, Meng, Su, Nan, Ni, Zhenhong, Jiang, Wanling, Chang, Jinhong, Chen, Hangang, Chen, Shuai, Xu, Xiaoling, Deng, Chuxia, Wang, Zhugang, Du, Xiaolan, Chen, Lin“…Our study provides a novel practical biological approach, which will, in combination with other therapies, including surgeries, help treat patients with AS while providing experimental clues for the biological therapies of other genetic skeletal diseases.…”
Publicado 2018
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6319por Xie, Shumin, Liu, Xiaoyu, Pan, Zhen, Chen, Xing, Peng, Anquan, Yin, Tuanfang, Ren, Jihao, Liu, Wei“…The GO and KEGG pathway analyses provided clues that these differentially expressed miRNAs might play essential roles in the etiopathogenesis of middle ear cholesteatoma, including cell proliferation, apoptosis, cell cycle, differentiation, bone resorption and remodeling process. …”
Publicado 2018
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6320por Znaidi, Sadri, van Wijlick, Lasse, Hernández‐Cervantes, Arturo, Sertour, Natacha, Desseyn, Jean‐Luc, Vincent, Frédéric, Atanassova, Ralitsa, Gouyer, Valérie, Munro, Carol A., Bachellier‐Bassi, Sophie, Dalle, Frédéric, Jouault, Thierry, Bougnoux, Marie‐Elisabeth, d'Enfert, Christophe“…We identified CRZ2, a transcription factor whose overexpression and deletion respectively increased and decreased early GI colonisation. Using clues from genome‐wide expression and gene‐set enrichment analyses, we found that the optimal activity of Crz2p occurs under hypoxia at 37°C, as evidenced by both phenotypic and transcriptomic analyses following CRZ2 genetic perturbation. …”
Publicado 2018
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