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  1. 6421
    “…Our findings provide important clues for further investigations of key genes and molecular mechanisms involved in the adaptation of G. daurica to harsh environments.…”
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    Comparative Analysis of Transcriptome Responses to Cold Stress in Galeruca daurica (Coleoptera: Chrysomelidae)
  2. 6422
    “…CONCLUSIONS: Age, sex, and hematuria may provide clues to differentiating NPB from UCB. Differences in cystoscopic features between NPB and UCB are of high diagnostic value. …”
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    Differentiating Nonfunctional Paraganglioma of the Bladder from Urothelial Carcinoma of the Bladder: Pitfalls and Breakthroughs
  3. 6423
    “…In conclusion, candidate genes affecting cartilage development in Yorkshire pigs were obtained by transcriptome analysis, and the clues showed that Day 14 to Day 28 is a more active and extensive period in cartilage developments, which played a key role in revealing the molecular mechanism of pig cartilage development basis, also compensating for vacancies in cartilage research.…”
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    Identification of mRNAs Related to Tibial Cartilage Development of Yorkshire Piglets
  4. 6424
    “…We found several peptides in non vertebrates that could be related to human natriuretic peptides, but a set of clues, as well as modeling and docking analysis, suggest that the natriuretic peptides undoubtedly appeared later than their receptors during animal evolution. …”
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    Natriuretic peptides appeared after their receptors in vertebrates
  5. 6425
    “…We demonstrated how a chemoproteomic approach can provide clues to the specificity of serine hydrolases by using a panel of neutral lipase inhibitors to identify an enzyme that reacts potently with a covalent monoacylglycerol lipase inhibitor. …”
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    Functional annotation of serine hydrolases in the asexual erythrocytic stage of Plasmodium falciparum
  6. 6426
    “…Additionally, they offer clues for the selection or development of cold-tolerant cultivars from the available germplasms of oil palm.…”
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    Correlation analysis of cold-related gene expression with physiological and biochemical indicators under cold stress in oil palm
  7. 6427
    “…The majority of our human genome transcribes into noncoding RNAs with unknown structures and functions. Obtaining functional clues for noncoding RNAs requires accurate base-pairing or secondary-structure prediction. …”
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    RNA secondary structure prediction using an ensemble of two-dimensional deep neural networks and transfer learning
  8. 6428
    “…Collectively, these data may provide novel clues with which to explore the precise etiology and mechanism underlying cryptorchidism and cryptorchidism-induced human infertility.…”
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    Bioinformatic identification of key genes and molecular pathways in the spermatogenic process of cryptorchidism
  9. 6429
    “…Some cytoskeleton regulatory proteins have been found to be related to AD pathogenesis. Our data show some clues that cytoskeletal reorganization may play roles in AD pathology. …”
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    MiR-409-5p as a Regulator of Neurite Growth Is Down Regulated in APP/PS1 Murine Model of Alzheimer’s Disease
  10. 6430
    “…Deciphering the discrete genetic determinant of infectivity in their envelope may provide clues for vaccine design. Methods: One hundred twenty-six clade B HIV-1 consensus envelope sequences from untreated acute and early infected individuals were compared to 105 sequences obtained from chronically infected individuals using next generation sequencing and molecular analyses. …”
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    HIV-1 Envelope Glycoprotein Amino Acids Signatures Associated with Clade B Transmitted/Founder and Recent Viruses
  11. 6431
    “…Analysis of NSC changes can provide important clues to reveal the adaptation mechanisms of plants to a specific environment. …”
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    Non-structural carbohydrates in maize with different nitrogen tolerance are affected by nitrogen addition
  12. 6432
    “…Hence, this research not only offers clues to the researcher who is interested in comparing the differences among resveratrol, quercetin and QRC, but also provides hints for the researcher who wants to explore QRC’s various synergies and its pharmacological and molecular mechanism.…”
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    Exploring the Pharmacological Mechanism of Quercetin-Resveratrol Combination for Polycystic Ovary Syndrome: A Systematic Pharmacological Strategy-Based Research
  13. 6433
    “…Diseases associated with CVS, including migraine, mitochondrial disorders, autonomic dysfunction, and psychiatric comorbidities, provide clues about pathophysiologic mechanisms and suggest potential therapies. …”
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    Cyclic vomiting syndrome: Pathophysiology, comorbidities, and future research directions
  14. 6434
    “…Compiling the information into one manuscript with all appropriate primary references provides quick clues to which studies have been completed under which conditions and what information has been reported. …”
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    The CLN3 gene and protein: What we know
  15. 6435
    “…Recently, the methods of exploiting the structure-based control principles of complex networks provide new clues for identifying minimum number of driver nodes to drive the state transition of large-scale complex networks from an initial state to the desired state. …”
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    A novel network control model for identifying personalized driver genes in cancer
  16. 6436
    “…More than 20 years of multidisciplinary studies have shown that brain zinc dyshomeostasis may play a critical role in AD progression, which provides encouraging clues for metal-targeted therapies in the treatment of AD. …”
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    Zinc transporters in Alzheimer’s disease
  17. 6437
    “…These findings provide important clues about the molecular mechanisms that regulate biomineralization in P. f. martensii.…”
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    PfmPif97-like regulated by Pfm-miR-9b-5p participates in shell formation in Pinctada fucata martensii
  18. 6438
    “…However, this approach is limited regarding the treatment of information of sequence motifs; distances caused by different motifs are mixed up. This hides clues to figure out how the samples are different. …”
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    Principal Component Analysis applied directly to Sequence Matrix
  19. 6439
    “…This study will provide useful clues for functional validation of desaturase genes and contribute to produce nutritionally important fatty acids by genetic modification in rice.…”
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    Genome-wide analysis of fatty acid desaturase genes in rice (Oryza sativa L.)
  20. 6440
    “…Our study could offer molecular clues for controlling the hazard of leaf spot and root rot diseases in wheat, thus improving wheat yield in the future.…”
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    Disclosure of the Molecular Mechanism of Wheat Leaf Spot Disease Caused by Bipolaris sorokiniana through Comparative Transcriptome and Metabolomics Analysis
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