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  1. 6501
    “…Taken together, our results provide new clues to understand the glucose tolerance in GH3 β-glucosidases.…”
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    A Highly Glucose Tolerant ß-Glucosidase from Malbranchea pulchella (MpBg3) Enables Cellulose Saccharification
  2. 6502
    “…The close link of visual clues to physiological responses is likely of clinical relevance. …”
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    Online Artículo Texto
    Visual stimulation with food pictures in the regulation of hunger hormones and nutrient deposition, a potential contributor to the obesity crisis
  3. 6503
    por Xia, Xuhua
    Publicado 2020
    “…Thus, viral surveys focused on decreasing CpG in viral RNA genomes may provide important clues about the selective environments and viral defenses in the original hosts.…”
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    Extreme Genomic CpG Deficiency in SARS-CoV-2 and Evasion of Host Antiviral Defense
  4. 6504
    “…Knowledge in this field has provided researchers with the clues and tools to propose the use of probiotics as a potential line of treatment for cervical cancer and has provided valuable insights into host–pathogen interaction dynamics within the female genital tract.…”
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    Vaginal Microbiota and HPV Infection: Novel Mechanistic Insights and Therapeutic Strategies
  5. 6505
    “…As several γ-CAs have been reported without measurable activity, this provides further clues as to critical residues. Our study reveals insights into the halophilic γ-CA activity and its unique adaptations. …”
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    Crystal Structure and Active Site Engineering of a Halophilic γ-Carbonic Anhydrase
  6. 6506
    “…Our study provides a critical resource for understanding the principles underlying primate arterial aging and contributes important clues to future treatment of age-associated vascular disorders.…”
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    A single-cell transcriptomic landscape of primate arterial aging
  7. 6507
    “…Thus, the serum metabolic profiling of gout patients treated with Tongfengtai granules changed, and the differential metabolites and related metabolic pathways might provide clues for understanding the mechanism of Tongfengtai granules.…”
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    Serum Metabolic Profiling Analysis of Gout Patients Treated with Traditional Chinese Medicine Tongfengtai Granules Based on Gas Chromatography-Mass Spectrometry
  8. 6508
    “…Our study demonstrated several important clues for future research on physiological and other phenotypic adaptation.…”
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    Genetic Adaptations of an Island Pit-Viper to a Unique Sedentary Life with Extreme Seasonal Food Availability
  9. 6509
    “…CONCLUSIONS: Altogether, these data suggest a role for promoting IFN-β signaling in glioblastoma and might provide clues to design future therapeutic approaches.…”
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    Interferon-β exposure induces a fragile glioblastoma stem cell phenotype with a transcriptional profile of reduced migratory and MAPK pathway activity
  10. 6510
    “…Although rare, both HPVG and PI are important radiological clues that usually indicate the presence of mesenteric ischemia with consequent intestinal necrosis.…”
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    Hepatic portal venous gas with pneumatosis intestinalis secondary to mesenteric ischemia in elderly patients: Two case reports
  11. 6511
    “…Taken together, this study may not only provide potential clues for further medical pathogenesis of COVID-19 and male fertility, but also indicate the clinical significance of the role of the ACE2 gene in cancer.…”
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    Expressions and significances of the angiotensin-converting enzyme 2 gene, the receptor of SARS-CoV-2 for COVID-19
  12. 6512
    “…A series of clinical trials associated with green tea extracts and EGCG are providing clues about significant potential of EGCG to mechanistically modulate wide ranging signal transduction cascades. …”
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    EGCG Mediated Targeting of Deregulated Signaling Pathways and Non-Coding RNAs in Different Cancers: Focus on JAK/STAT, Wnt/β-Catenin, TGF/SMAD, NOTCH, SHH/GLI, and TRAIL Mediated Signaling Pathways
  13. 6513
    “…Recent advances have, however, provided some intriguing clues. It appears that inactive receptor phot1 is found dispersed in a monomeric form at the plasma membrane in darkness. …”
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    The continuing arc toward phototropic enlightenment
  14. 6514
    “…Candidate targets related to CVD were collected from Therapeutic Targets Database and PharmGkb database and analyzed using ClueGO plugin in Cytoscape. KEGG pathway was enriched and analyzed through the EnrichR platform, and protein-protein interaction networks were calculated by STRING platform. …”
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    Network Pharmacology-Based Approach to Investigate the Mechanisms of Mahai Capsules in the Treatment of Cardiovascular Diseases
  15. 6515
    “…Long disease duration, homogenous pigmentation pattern, presence of white streaks and jagged edges are the main clues to FM.…”
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    Dermoscopic findings of fungal melanonychia
  16. 6516
    “…In this aspect, multiple rs‐fMRI scans from single subjects can provide interesting clues about the rs‐fMRI patterns, though scan‐to‐scan variability pose challenges. …”
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    Maximizing dissimilarity in resting state detects heterogeneous subtypes in healthy population associated with high substance use and problems in antisocial personality
  17. 6517
    “…The apparent trend among apex predators for some evolving into feeding on small zooplankton is of interest for understanding the associated shifts in anatomy and behaviour, while the spatial and temporal distribution gives clues to an inherent relationship with ocean primary productivity and how past and future perturbations to these may impact on the different tiers of the food web. …”
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    Was the Devonian placoderm Titanichthys a suspension feeder?
  18. 6518
    por Lu, Huixia, Marti, Jordi
    Publicado 2020
    “…The calculations reported here offer detailed free energy landscapes of melatonin embedded in model cell membranes and reveal microscopic information on its transition between free energy minima, including the location of relevant transition states, and provide clues on the role of cholesterol in the cellular absorption of small molecules.…”
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    Cellular absorption of small molecules: free energy landscapes of melatonin binding at phospholipid membranes
  19. 6519
    “…Insight into the influence of TNF‐α inhibitors on lung immune cells may provide clues as to what drives inflammation in sarcoidosis and improve our understanding of treatment outcomes. …”
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    Changes in lung immune cells related to clinical outcome during treatment with infliximab for sarcoidosis
  20. 6520
    “…In the present study, we sought to answer the question of whether the musical rhythm perception of Chinese children with RD is intact or not, providing further clues on how reading and music might be interlinked across languages. …”
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    Neural Responses to Musical Rhythm in Chinese Children With Reading Difficulties
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