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  1. 6721
    “…In addition, exosomes carry molecules on their surface that provides clues regarding their origin, making it possible to sort vesicle types and enrich signatures from tissue-specific origins. …”
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    Exosome-based liquid biopsies in cancer: opportunities and challenges
  2. 6722
    “…Further, we also discuss the role of chemotherapy-induced TME remodeling in modulating TNBC immune response and tumor progression with emphasis on DAMPs-associated molecules including high mobility group box1 (HMGB1), exosomes, and sphingosine-1-phosphate receptor 1 (S1PR1), which may provide us with new clues to explore effective combined treatment options for TNBC.…”
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    Tumor Microenvironment: Key Players in Triple Negative Breast Cancer Immunomodulation
  3. 6723
    por Louis, Elan D., McCreary, Morgan
    Publicado 2021
    “…DISCUSSION: Precise prevalence estimates are important because they form the numerical basis for public health initiatives and offer clues about underlying biological factors of mechanistic importance. …”
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    How Common is Essential Tremor? Update on the Worldwide Prevalence of Essential Tremor
  4. 6724
    por Cheng, Xu, Shi, Bing, Li, Jingtao
    Publicado 2021
    “…Based on the most up-to-date literature, we delineated the pivotal cell populations regulating craniofacial muscle repair and identified clues that might elucidate the distinct embryonic origin and injury response in craniofacial muscle cells.…”
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    Distinct Embryonic Origin and Injury Response of Resident Stem Cells in Craniofacial Muscles
  5. 6725
    por Webster, Paula J., Wang, Shuo, Li, Xin
    Publicado 2021
    “…We also propose two possible teaching approaches: (1) a standard method of teaching progressively from simple drawings and cartoon characters to more complex audio-visual video clips of genuine human expressions of emotion with context clues or (2) teaching in a field of images that includes posed and genuine emotions to improve generalizability before progressing to more complex audio-visual stimuli. …”
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    Review: Posed vs. Genuine Facial Emotion Recognition and Expression in Autism and Implications for Intervention
  6. 6726
    “…Altogether, our findings offer novel data-driven clues for the field's larger quest to ascertain the very foundations of mindfulness.…”
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    A network approach to the five-facet model of mindfulness
  7. 6727
    “…It also affords an overview about what we have achieved and a reflection on how much remains to be done in this field, further addressing encouraging clues for the advance of DDR targeted therapy.…”
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    Exploiting DNA Damage Repair in Precision Cancer Therapy: BRCA1 as a Prime Therapeutic Target
  8. 6728
    “…This rare case of patient S19_137 highlights the potential causal importance of the PMC for integrating self-referential information and provides clues for future mechanistic studies of self-dissociation in neuropsychiatric populations.…”
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    Altered sense of self during seizures in the posteromedial cortex
  9. 6729
    “…Identifying potential prognostic markers of neuroblastoma can provide clues for early diagnosis, recurrence, and treatment. …”
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    Identification of Prognostic Genes in Neuroblastoma in Children by Weighted Gene Coexpression Network Analysis
  10. 6730
    “…Further clarification of the functional and synergistic mechanisms among MQC mechanisms may provide useful clues for use in developing novel IDD treatments.…”
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    Mitochondrial quality control in intervertebral disc degeneration
  11. 6731
    “…In summary, this study first summarized the changes in the expression pattern of piRNA in preeclampsia and provided new clues for the regulatory role of piRNA in the human placenta.…”
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    Identification and characterization of Piwi-interacting RNAs in human placentas of preeclampsia
  12. 6732
    “…These novel SEPs might not only provide new clues for the annotation of noncoding elements in the genome but also serve as a valuable resource for functional study.…”
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    Deeply Mining a Universe of Peptides Encoded by Long Noncoding RNAs
  13. 6733
    “…In each group, the CCTA offered an advantage and provided specific clues for surgical or interventional management. …”
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    Cardiac computed tomography angiography in the pre-operative assessment of congenital heart disease in Thailand
  14. 6734
    “…Our study highlights how plasmid integration and rearrangements can contribute to the spread of bla (OXA-48)-like genes, which provides important clues for clinical prevention of the dissemination of K. pneumoniae strains carrying bla (OXA-48)-like carbapenemases.…”
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    Emergence of carbapenem-resistant Klebsiella pneumoniae harbouring bla (OXA-48)-like genes in China
  15. 6735
    “…This study provides important clues for the understanding of the function of N-linked glycosylation in metabolism, immunity, and metamorphosis.…”
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    Identification of N-linked Glycoproteins in Silkworm Serum Using Con A Lectin Affinity Chromatography and Mass Spectrometry
  16. 6736
    “…Overall, this study provided reliable clues for improving the ATO efficacy in AML.…”
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    Genetic Expression Screening of Arsenic Trioxide-Induced Cytotoxicity in KG-1a Cells Based on Bioinformatics Technology
  17. 6737
    por Juhlin, C. Christofer, Zedenius, Jan
    Publicado 2021
    “…Although this association remains purely speculative, future investigations of this tumor phenotype could perhaps yield novel insights regarding the frequency of this histological variant, potential clinical associations, and clues regarding influencing factors.…”
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    Parathyroid Adenoma With Respiratory-Like Epithelium: Case Report of a Potential Mimic With Unknown Etiology
  18. 6738
    por Yeo, Min-Kyung, Yoon, Nara, Bae, Go Eun
    Publicado 2021
    “…The molecular characteristics of GI MiNENs could provide clues to the pathogenic origin and progression of GI MiNENs.…”
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    Clinicopathologic and Molecular Characteristics of Gastrointestinal MiNENs
  19. 6739
    “…Exploring the pathogenesis of this lethal tumor could provide clues for developing appropriate therapeutic drugs. …”
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    UBE3A activates the NOTCH pathway and promotes esophageal cancer progression by degradation of ZNF185
  20. 6740
    por Zhang, Yuhao, Sun, Dawei
    Publicado 2021
    “…CONCLUSION: The results expand our knowledge on immune-related gene polymorphisms in HNC and provide clues for further functional study on the pathogenesis of HNC.…”
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    Genetic Polymorphisms of FCRL3, NLRP3 and IL2 are Associated with the Risk of Head and Neck Cancer in a Chinese Population
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