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7081por Enokizono, Mikako, Aida, Noriko, Yagishita, Akira, Nakata, Yasuhiro, Ideguchi, Reiko, Kurokawa, Ryo, Kono, Tatsuo, Moritani, Toshio, Mori, Harushi“…The diagnosis of IEMs relies on biochemical and genetic tests, but neuroimaging studies also provide important clues to the correct diagnosis and enable the conditions to be distinguished from other, more common causes of encephalopathy, such as hypoxia–ischemia. …”
Publicado 2023
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7082por Guo, Weiming, Jin, Peng, Li, Ruomei, Huang, Lu, Liu, Zhen, Li, Hairui, Zhou, Ting, Fang, Bing, Xia, Lunguo“…We also found several mechanistic clues that cdkn1a participates in osteoclast differentiation by regulating its upstream signaling cascades. …”
Publicado 2023
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7083por Qi, Luying, Yu, Qingtao, Liang, Zhengyan, Lu, Yang, Ma, Zhihua, Hou, Chujie, Zhu, Zhiyong, Chen, Liyong“…These findings provide experience and clues for local governments to improve the psychological status and dietary habits of residents during the local COVID-19 outbreak in the post-pandemic era.…”
Publicado 2023
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7084“…With advancement of organoid technology, brain organoids offer a promising tool for unravelling pathophysiologic clues and potential therapeutic options for neuropsychiatric complications of COVID-19.…”
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7085por Zhang, Heyu, He, Yan, Wu, Xiaomin, Huang, Peixiang, Qin, Wenkang, Wang, Fan, Ye, Juxiang, Huang, Xirui, Liao, Yanfang, Chen, Hang, Guo, Limei, Shi, Xueying, Luo, Lin“…Results show that the classification and captioning tasks achieve better results with reason labels, provide explainable clues for doctors to understand and make the final decision and thus can support a better experience of human-AI collaboration in pathological diagnosis. …”
Publicado 2023
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7086“…Together, these findings paint a complex landscape of the nature of infection but provide clues as to what may be protective early on in SARS-CoV-2 disease course. …”
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7087“…This study demonstrated the strategy of improving the energy release of boron-containing metalized explosives through the design of an explosive microstructure, which provides important clues for the design of higher-energy metalized explosives.…”
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7088por Yi, Li, Fan, Qingying, Wang, Haikun, Fan, Haoran, Zuo, Jing, Wang, Yuxin, Wang, Yang“…In summary, our study provides powerful clues for future exploration of the mechanisms of S. suis biofilm formation. …”
Publicado 2022
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7089“…Thus, these markers could provide clues into underlying mechanisms and predict mortality.…”
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7090por Qiu, Heng, Hosking, Christopher, Rothzerg, Emel, Samantha, Ariela, Chen, Kai, Kuek, Vincent, Jin, Haiming, Zhu, Sipin, Vrielink, Alice, Lim, Kevin, Foley, Michael, Xu, Jiake“…Further investigation on the mechanism of action of ADR3 revealed that it can inhibit hRANKL-mediated signaling pathways, supporting the in vitro functional observations. These clues collectively indicate that hRANKL antagonist ADR3 attenuates osteoclast differentiation and bone resorption, with the potential to serve as a novel therapeutic to protect against bone loss.…”
Publicado 2023
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7091“…BDH2 mRNA level significantly anti-correlate with tumour grade. We offer clues on the potential of ACAT1 as a biomarker of mitochondrial activity, but future studies are needed to establish this concept.…”
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7092“…Examining the interaction between EBV and immunotherapies that have demonstrated efficacy in MS offers clues to the validity of these hypotheses. The efficacy of B cell depleting therapies could be consistent with a hypothesis that EBV‐infected B cells drive MS; however, loss of T cell control of B cells does not exacerbate MS. …”
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7093“…This study may provide clues for the prevention and therapy of cardiac fibrosis. …”
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7094Characteristics and related factors of family functioning in Chinese families during early pregnancypor Qin, Xuemei, Zhang, Weiling, Xu, Shuyin, Ma, Mohan, Fan, Xing, Nie, Xueqing, Liu, Jin, Ju, Yumeng, Zhang, Li, Li, Lingjiang, Li, HaoLun, Liu, Bangshan, Zhang, Yan“…CONCLUSIONS: The study reinforced the important clues of family functioning during early pregnancy. …”
Publicado 2023
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7095“…Our research provided essential clues for in-depth comprehension of the mechanism of NSCLC occurrence and development and also provided the basis for NSCLC treatment.…”
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7096por Billington, Karen, Halliday, Clare, Madden, Ross, Dyer, Philip, Barker, Amy Rachel, Moreira-Leite, Flávia Fernandes, Carrington, Mark, Vaughan, Sue, Hertz-Fowler, Christiane, Dean, Samuel, Sunter, Jack Daniel, Wheeler, Richard John, Gull, Keith“…Here, using fluorescence microscopy and cell lines expressing endogenously tagged proteins, we mapped the subcellular localization of 89% of the T. brucei proteome, a resource we call TrypTag. We provide clues to function and define lineage-specific organelle adaptations for parasitism, mapping the ultraconserved cellular architecture of eukaryotes, including the first comprehensive ‘cartographic’ analysis of the eukaryotic flagellum, which is vital for morphogenesis and pathology. …”
Publicado 2023
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7097“…Collectively, this work demonstrated comprehensively the genomic alterations and clinical characteristics of STGs, which may offer new clues to explore the mechanisms on a molecular level between SARS-CoV-2 virus and cancers as well as provide new clinical guidance for cancer patients who are threatened by the COVID-19 epidemic.…”
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7098por Power, Beverley“…DISCUSSION: This can be used as a basis for care and research, including standards, benchmarking, transition and helping improvements in healthcare, education, family life and social settings. Potentially holding clues as to the etiology and pathology of the condition and an opportunity to further explore theories and unanswered questions. …”
Publicado 2023
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7099“…Fourteen studies revealed EVs with functional cargoes could be used to make the diagnosis of liver failure and provide clues for early warning and prognostic assessment of patients with liver failure. …”
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7100“…In conclusion, the present study identified 14 EMT-related genes and 30 genes involved in the PI3K/AKT/mTOR pathway in cervical cancer, and they might provide novel clues for future treatment. The MMP family may be a notable factor associated with tumor cells and immune cells.…”
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