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  1. 7301
    “…These results should provide basic clues for applying aspects of the TRx system as a therapeutic molecule in cardiovascular diseases. …”
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    Expression Pattern of the Thioredoxin System in Human Endothelial Progenitor Cells and Endothelial Cells Under Hypoxic Injury
  2. 7302
    por Iwata, Hiroaki, Gotoh, Osamu
    Publicado 2011
    “…Our findings may afford additional clues to understanding of evolution of splicing mechanisms.…”
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    Comparative analysis of information contents relevant to recognition of introns in many species
  3. 7303
    “…Similarity of gene expression profiles provides important clues for understanding the biological functions of genes, biological processes and metabolic pathways related to genes. …”
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    OryzaExpress: An Integrated Database of Gene Expression Networks and Omics Annotations in Rice
  4. 7304
    “…Based on the abundant changes in these proteins, together with their putative functions, we proposed a possible protein network that provides new insights into oxidative stress response in the rice root apoplast and clues for the further functional research of target proteins associated with H(2)O(2) response.…”
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    Comparative Proteomics Analysis of the Root Apoplasts of Rice Seedlings in Response to Hydrogen Peroxide
  5. 7305
    “…A deeper understanding of the mechanism of ASA action may provide clues to the differences between host response in the acute and chronic T. cruzi infection.…”
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    Aspirin Treatment of Mice Infected with Trypanosoma cruzi and Implications for the Pathogenesis of Chagas Disease
  6. 7306
    “…The composite space-time disease variation is the result of underlining attribute mechanisms that could provide clues about the physiologic and demographic determinants of disease transmission and also guide the appropriate allocation of medical resources to control the disease. …”
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    Hand, foot and mouth disease: spatiotemporal transmission and climate
  7. 7307
    “…In the future, these findings will be searched for directed networks likely involved in cutaneous fibroproliferation. These clues may lead to a better understanding of the systems biology of cutaneous fibroproliferation, and ultimately prevention and treatment of hypertrophic scarring.…”
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    Functional Genomics Unique to Week 20 Post Wounding in the Deep Cone/Fat Dome of the Duroc/Yorkshire Porcine Model of Fibroproliferative Scarring
  8. 7308
    “…Although IP6K has not yet been identified in plant chromosomes, there are many clues suggesting its presences in vegetal cells. …”
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    IP6K gene identification in plant genomes by tag searching
  9. 7309
    “…The modelling of iron homeostasis in relation to the main features of metabolism, energy production and oxidative stress may provide new clues to the ways in which changes in biological processes in a normal cell lead to disease. …”
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    A Boolean probabilistic model of metabolic adaptation to oxygen in relation to iron homeostasis and oxidative stress
  10. 7310
    “…We have demonstrated using clues from the literature that most of these new motifs discovered by F-Motif are indeed novel. …”
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    Discovery of Protein Phosphorylation Motifs through Exploratory Data Analysis
  11. 7311
    “…In particular, we explore the use of MeSH terms, manually assigned to documents by trained annotators, as clues to select important text segments from the full text documents. …”
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    Online Artículo Texto
    MeSH: a window into full text for document summarization
  12. 7312
    “…A thorough physical examination (e.g., angiokeratoma, corneal opacities) and simple non-invasive sensory perception tests could provide clues to the diagnosis of Fabry disease. Reported early clinical benefits of enzyme replacement therapy include reduction of neuropathic pain, and adequate management of residual pain to a tolerable and functional level can substantially improve the quality of life for patients. …”
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    Early diagnosis of peripheral nervous system involvement in Fabry disease and treatment of neuropathic pain: the report of an expert panel
  13. 7313
    “…These findings suggested a potential role of abnormal HRH4 expression in the progression of CRCs and provided some new clues for the application of HRH4-specific agonist or antagonist in the molecular therapy of CRCs.…”
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    Attenuated expression of HRH4 in colorectal carcinomas: a potential influence on tumor growth and progression
  14. 7314
    “…CONCLUSIONS: Our refined definition of PDZ-binding motifs should provide important clues for identifying functional PDZ-binding motifs and proteins involved in signal transduction.…”
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    Evolutionarily conserved bias of amino-acid usage refines the definition of PDZ-binding motif
  15. 7315
    “…Mitochondrial dysfunction and oxidative stress have been implicated in the pathophysiology of many diseases; therefore, the ability to determine ΔΨm and ROS can provide important clues about the physiological status of the cell and the function of the mitochondria. …”
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    Determination of Mitochondrial Membrane Potential and Reactive Oxygen Species in Live Rat Cortical Neurons
  16. 7316
    “…Such alterations may serve as valuable tools for diagnosis and classification of tumors, prediction of clinical outcome, disease monitoring, and choice of therapy as well as for providing clues to the location of crucial cancer-related genes. …”
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    SKY analysis revealed recurrent numerical and structural chromosome changes in BDII rat endometrial carcinomas
  17. 7317
    por Cao, Heping
    Publicado 2011
    “…Understanding the roles of DGATs will help to create transgenic plants with value-added properties and provide clues for therapeutic intervention for obesity and related diseases. …”
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    Structure-Function Analysis of Diacylglycerol Acyltransferase Sequences from 70 Organisms
  18. 7318
    “…The observed increase in the levels of several lipids in high-BI patients may provide novel clues regarding the biological pathways involved in the immunomodulation of leprosy. …”
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    Serum Metabolomics Reveals Higher Levels of Polyunsaturated Fatty Acids in Lepromatous Leprosy: Potential Markers for Susceptibility and Pathogenesis
  19. 7319
    “…There are two differences in gene repertoire compared with typical S. aureus that may be significant clues as to the genetic basis underlying the successful emergence of S. aureus as a pathogen. …”
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    A Very Early-Branching Staphylococcus aureus Lineage Lacking the Carotenoid Pigment Staphyloxanthin
  20. 7320
    “…Overall, to our best knowledge, our study represents the most comprehensive characterization of HBV-related HCC transcriptome including exon level expression changes and novel splicing variants, which illustrated the power of RNA-seq and provided important clues for understanding the molecular mechanisms of HCC pathogenesis at system-wide levels.…”
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    RNA-Seq Analyses Generate Comprehensive Transcriptomic Landscape and Reveal Complex Transcript Patterns in Hepatocellular Carcinoma
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