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  1. 7401
    “…CONCLUSIONS: Our systematic analysis may provide important clues to the function and evolution of ncRNAs in T. rubrum. …”
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    Identification and characterisation of non-coding small RNAs in the pathogenic filamentous fungus Trichophyton rubrum
  2. 7402
    “…The combination of ENMs with set theory allows studying the invasive biology of symbionts and provides clues about biogeographic barriers due to abiotic or biotic factors limiting the expansion of the symbiont in different regions of the invasive range. …”
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    Invasion biology in non-free-living species: interactions between abiotic (climatic) and biotic (host availability) factors in geographical space in crayfish commensals (Ostracoda, Entocytheridae)
  3. 7403
    “…Explanations for ethnic differences in DNA methylation in association with smoking may provide valuable clues to disease pathways.…”
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    Differences in smoking associated DNA methylation patterns in South Asians and Europeans
  4. 7404
    “…The main assets of the RD-chip are: i) the robustness of the genetic information that underscores the most probable candidates, ii) the invaluable clues in cases of shared haplotypes, which are indicative of a common founder effect, and iii) the detection of extended haplotypes over closely mapping genes, which substantiates cosegregation, although the assumptions in which the genetic analysis is based could exceptionally lead astray. …”
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    Combined Genetic and High-Throughput Strategies for Molecular Diagnosis of Inherited Retinal Dystrophies
  5. 7405
    por Keir, Jeff
    Publicado 2014
    “…Lesions were scored for presence of classical criteria for facial LM; modified pattern analysis (“Chaos and Clues”) criteria; and the presence of two novel criteria: a lentigo-like pigment pattern lacking a lentigo-like border, and large polygons. …”
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    Dermatoscopic features of cutaneous non-facial non-acral lentiginous growth pattern melanomas
  6. 7406
    por Li, Yu, Wang, Nai'ang, Zhang, Chengqi
    Publicado 2014
    “…Abrupt climate events are always associated with changes in large-scale circulation patterns; therefore, investigations into abrupt climate changes provide clues for responses of circulation patterns to extreme climate events. …”
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    An Abrupt Centennial-Scale Drought Event and Mid-Holocene Climate Change Patterns in Monsoon Marginal Zones of East Asia
  7. 7407
    “…In this review, we provide recent perspectives of ER and ER body formation in A. thaliana, and discuss clues for the functions of ER bodies. We highlight defense strategies against biotic stress that are unique for the Brassicales order, and discuss how ER structures could contribute to these strategies.…”
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    ER bodies in plants of the Brassicales order: biogenesis and association with innate immunity
  8. 7408
    “…In addition, the reconstructed map elucidates several novel cancer signaling pathways, which may provide clues to support the application of anti-cancer therapeutics to PAH. …”
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    An evidence-based knowledgebase of pulmonary arterial hypertension to identify genes and pathways relevant to pathogenesis
  9. 7409
    “…The comparative GPCR expression study presented here gives clues for new pathways specifically used by GSCs and unveils novel potential therapeutic targets.…”
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    Comparative Expression Study of the Endo–G Protein Coupled Receptor (GPCR) Repertoire in Human Glioblastoma Cancer Stem-like Cells, U87-MG Cells and Non Malignant Cells of Neural Origin Unveils New Potential Therapeutic Targets
  10. 7410
    “…Examination of mutants and deletion fragments located at various sites of optineurin gene provide clues as to what regions of the gene may play a critical role in the development of pathologic consequences.…”
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    Effects of mutations and deletions in the human optineurin gene
  11. 7411
    “…We also offer the first clues on the mechanisms behind gene dosage balancing in an organism that undergoes sexual reversal. …”
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    Epigenetic modification and inheritance in sexual reversal of fish
  12. 7412
    “…Identification of specific geographical areas with high risk (clusters) may give clues to potential environmental risk factors. The aim of this study was to investigate whether clusters of breast cancer existed in space and time in Denmark, using 33 years of residential histories. …”
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    Space-time clusters of breast cancer using residential histories: A Danish case–control study
  13. 7413
    “…We highlighted the application of this well-annotated genomic framework in generating hypothetical link of human-biased regulations to human-specific traits, by using mechanistic characterization of the DIEXF gene as an example that provides novel clues to the understanding of digestive system reduction in human evolution. …”
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    Evolutionary Interrogation of Human Biology in Well-Annotated Genomic Framework of Rhesus Macaque
  14. 7414
    “…We suggest that further investigation of this association could give clues to the aetiology of psychosis.…”
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    The prevalence of psychosis in epilepsy; a systematic review and meta-analysis
  15. 7415
    “…Evolutionary analyses might provide some clues to aid in an understanding of their functional diversification. …”
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    Genome-Wide Analyses of a Plant-Specific LIM-Domain Gene Family Implicate Its Evolutionary Role in Plant Diversification
  16. 7416
    “…After we sequenced R. decussatus transcriptome we have designed an oligo microarray capable of contributing to provide some clues on molecular response of the clam to Perkinsiosis. …”
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    mRNA-Seq and microarray development for the Grooved carpet shell clam, Ruditapes decussatus: a functional approach to unravel host -parasite interaction
  17. 7417
    “…These results will provide clues for research on the pathogenic mechanisms of WBD phytoplasma and will also provide a perspective about the genome sequencing of other phytoplasmas and obligate organisms.…”
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    Comparative Genome Analysis of Wheat Blue Dwarf Phytoplasma, an Obligate Pathogen That Causes Wheat Blue Dwarf Disease in China
  18. 7418
    “…Interestingly, while the binding pocket and the binding contacts of RES to ERα are similar to those of pure agonist diethylstilbestrol (DES), the binding energy is much less and the hydrogen bonding contacts also differ providing clues for the partial agonistic character of RES on ERα. …”
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    Structural insights into Resveratrol’s antagonist and partial agonist actions on estrogen receptor alpha
  19. 7419
    “…Existing evidence associates chronic infection by NTHi to the progression of the chronic respiratory disease, but specific features of NTHi associated with persistence have not been comprehensively addressed. To provide clues about adaptive strategies adopted by NTHi during persistent infection, we compared sequential persistent isolates with newly acquired isolates in sputa from six patients with chronic obstructive lung disease. …”
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    Characterization of Nontypable Haemophilus influenzae Isolates Recovered from Adult Patients with Underlying Chronic Lung Disease Reveals Genotypic and Phenotypic Traits Associated with Persistent Infection
  20. 7420
    “…Moreover, the present protein structures provide some clues about the determinants of the extraordinary stability of the biomolecule. …”
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    A Loose Domain Swapping Organization Confers a Remarkable Stability to the Dimeric Structure of the Arginine Binding Protein from Thermotoga maritima
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