“…Thus, our study provides potential clues in the search for novel therapeutics and fatty lipid control options for HCV patients.…”
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“…Tumor necrosis factor-alpha (TNFα), a pro-inflammatory cytokine, is linked to UVR-induced development of SCC. To find clues about the mechanisms by which TNFα may promote UVR-induced development of SCC, we investigated changes in the expression profiling of microRNAs (miRNA), a novel class of short noncoding RNAs, which affects translation and stability of mRNAs. …”
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“…This question is important both for using miRNAs as biological markers and for clues to miRNA function in the regulation of circadian gene expression. …”
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“…In addition, the documentation of the antibiotic resistance rates of MTBC clinical isolates to the antibiotic treatments most often clinically prescribed over a decade provides valuable clues and reference points for effective mycobacterial control.…”
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“…OBJECTIVE: To precisely describe the initial psychiatric presentation of patients with anti-NMDA receptor (NMDAR) antibodies encephalitis (anti-NMDAR encephalitis) to identify potential clues enhancing its early diagnosis. METHODS: We retrospectively studied the French Reference Centre medical records of every adult patient with anti-NMDAR encephalitis to specify the patients' initial psychiatric symptoms leading to hospitalization in a psychiatric department and the reasons underlying the diagnosis of anti-NMDAR encephalitis. …”
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“…BACKGROUND: Predicting piwi-interacting RNA (piRNA) is an important topic in the small non-coding RNAs, which provides clues for understanding the generation mechanism of gamete. …”
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“…The characterization of SET domain-containing genes in G. raimondii provides useful clues for further revealing epigenetic regulation under HT and function diversification during evolution.…”
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“…Thus the study of microbial metabolisms and evolution provides an important link between extant biota and the clues from the geologic record. Here, we consider the physiology of cyanobacteria (the only microorganisms capable of oxygenic photosynthesis), their co‐occurrence with anoxygenic phototrophs in a variety of environments and their persistence in low‐oxygen environments, including in water columns as well as mats, throughout much of Earth's history. …”
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“…Theses results might provide useful clues for the control of the startup processes and maintaining high efficiency of such bioreactors. …”
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“…Recently, research has progressively highlighted on clues from conventional use of herbal medicines to introduce new anticancer drugs. …”
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“…Our results clearly showed that enhancing ghrelin and blocking CRF receptor 2 signaling in the brain accelerated gastric emptying, which provided important clues for a new therapeutic avenue in ameliorating anorexia and gastric ileus found in various chronic wasting disorders.…”
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“…Further investigation of TSG function in vivo may provide new clues for uncovering the secrets of spermatogenesis. …”
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“…In the absence of this finding, other multimodal imaging clues and a careful history may aid in recognizing this diagnosis. …”
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“…Thus, the neuroimaging results provide evidence of brain transfer in the absence of behavioral transfer, providing new clues about the consequences of long-term training associated with competitive Scrabble expertise.…”
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“…The TLR4 crystal structures demonstrate extensive contact with their ligands and provide clues as to how they discriminate a broad array of molecules and activate or attenuate innate, as well as adaptive, responses resulting from these interactions. …”
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“…Our data will provide new clues for in-depth study of photoprotective mechanisms in diatoms. …”
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“…CONCLUSION: The current findings greatly enhance our understanding of the mechanisms of induced defense response in rice plants against C. suppressalis infestation at molecular and biochemical levels, and will provide clues for development of insect-resistant rice varieties. …”
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“…Comprehensive analysis of these miRNA profiles not only provides useful clues for understanding prion biology but also is beneficial in the search for possible diagnostic marker(s) for prion diseases.…”
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“…This information may yield clues to design novel therapeutic strategies in diseases characterized by inflammation and fibrosis.…”
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“…This study provides new clues to the understanding of the signalling mechanism responsible for VEGF production in response to different masticatory functions at the protein level.…”
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