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7541“…We will also discuss how taking a closer look into the evolution of key complement components not only made the functional connection between complement and metabolism rather “predictable” but how it may also give clues for the discovery of additional roles for complement in basic cellular processes.…”
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7542por Batra, Ritu, Saripalli, Gautam, Mohan, Amita, Gupta, Saurabh, Gill, Kulvinder S., Varadwaj, Pritish K., Balyan, Harindra S., Gupta, Pushpendra K.“…The results of the present study have allowed better understanding of structure and evolution of the genes and the encoded proteins and provided clues for exploitation of variability in these genes for engineering thermostable AGPase.…”
Publicado 2017
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7543“…These general principles offer important clues for designing treatment strategies for B-cell malignancies.…”
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7544por Kreis, Christian, Lupatsch, Judith E., Niggli, Felix, Egger, Matthias, Kuehni, Claudia E., Spycher, Ben D.“…BACKGROUND: Many studies have observed space-time clustering of childhood leukemia (CL) yet few have attempted to elicit etiological clues from such clustering. We recently reported space-time clustering of CL around birth, and now aim to generate etiological hypotheses by comparing clustered and nonclustered cases. …”
Publicado 2017
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7545“…In conclusion, the woman’s LOC appears to be independently influenced by a number of characteristics which may give clues as to possible mechanisms—and how internality may be supported in the future. …”
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7546por Liang, Xue-hong, Rong, Liucheng, He, Guangsheng, He, Hailong, Lin, Shengyun, Yang, Yan, Xue, Yao, Fang, Yongjun“…This initial analysis provides valuable clues for further study of TGF-β1 pathway genes in acquired AA.…”
Publicado 2016
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7547“…Gene expression patterns during different stages of plant development can provide clues toward the understanding of its biological functions. …”
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7548por Li, Chuang, Gong, Wenbing, Zhang, Lin, Yang, Zhiquan, Nong, Wenyan, Bian, Yinbing, Kwan, Hoi-Shan, Cheung, Man-Kit, Xiao, Yang“…Our study has provided candidate markers for marker-assisted selection (MAS) and useful clues for understanding the genetic architecture of agronomic traits in the shiitake mushroom.…”
Publicado 2017
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7549por Chen, Guiqin, Nie, Shuke, Han, Chao, Ma, Kai, Xu, Yan, Zhang, Zhentao, Papa, Stella M., Cao, Xuebing“…These results support the association of p-ERK1/2, ΔFosB, p-H3 to the regulation of TH and ARNT in the mechanisms of LID, and pinpoint other gene regulatory changes, thus providing clues for identifying new targets for LID therapy.…”
Publicado 2017
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7550por Lee, Sung Hak, Hyun, Seung Jung, Kim, Tae-Min, Rhee, Je-Keun, Park, Hyeon-Chun, Sung, Min Kim, Kim, Sung Soo, Hyeok, Chang An, Lee Hyung, Sug, Chung, Yeun-Jun“…Our findings provide resource for understanding colon premalignant lesions and for identifying genomic clues for differential diagnosis and therapy options for colon adenomas and carcinomas.…”
Publicado 2016
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7551“…High cost of treatment is a barrier to the uptake of health services in low resource settings, therefore an exploration of the cost of malaria management will reveal possible components that may benefit from intervention and thus reveal important clues for improving access to malaria treatment. …”
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7552por Hur, Eun-Hye, Jung, Seung-Hyun, Goo, Bon-Kwan, Moon, Juhyun, Choi, Yunsuk, Choi, Dae Ro, Chung, Yeun-Jun, Lee, Je-Hwan“…Our in vitro and in vivo models of HMA-resistant cell lines will provide clues for the elucidation of molecular mechanisms related to the development of resistance to HMA and tools for the application of novel therapeutics for AML and MDS.…”
Publicado 2016
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7553por Greenwood, C., Clement, J.G., Dicken, A.J., Evans, J.P.O., Lyburn, I.D., Martin, R.M., Rogers, K.D., Stone, N., Adams, G., Zioupos, P.“…Overall, this study has not only highlighted that the fracture model based upon BMD could potentially be improved with inclusion of other microarchitecture parameters, but has also given us clear clues as to which of them are more influential in this role.…”
Publicado 2015
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7554por Aslanger, Emre, Assous, Benjamin, Bihry, Nicolas, Beauvais, Florence, Logeart, Damien, Cohen-Solal, Alain“…CONCLUSION: Comprehensive evaluation of resting cardiovascular mechanics can give clues about exercise-recruited reserves of the cardiovascular system. …”
Publicado 2016
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7555por Zhao, Xia, Shen, Mengyu, Jiang, Xingyu, Shen, Wei, Zhong, Qiu, Yang, Yuhui, Tan, Yinling, Agnello, Melissa, He, Xuesong, Hu, Fuquan, Le, Shuai“…In addition, knowledge of the host pathways inhibited by phage may provide clues to novel drug targets. However, the effect of phage on bacterial gene expression and metabolism is still poorly understood. …”
Publicado 2017
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7556por Mutai, Hideki, Kenyon, Lawrence C, Locke, Emily, Kikuchi, Nami, Oberholtzer, John Carl“…The control elements identified here may provide clues to the tissue-specific expression of this K(+ )channel.…”
Publicado 2004
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7557por DeLeon, Orlando, Hodis, Hagit, O’Malley, Yunxia, Johnson, Jacklyn, Salimi, Hamid, Zhai, Yinjie, Winter, Elizabeth, Remec, Claire, Eichelberger, Noah, Van Cleave, Brandon, Puliadi, Ramya, Harrington, Robert D., Stapleton, Jack T., Haim, Hillel“…We sought to identify “clues” to predict the observed historic diversification patterns. …”
Publicado 2017
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7558por Wang, Lina, Yu, Hongyao, Cheng, Hui, He, Ke, Fang, Zhuoqing, Ge, Laixiang, Cheng, Tao, Jin, Ying“…Altogether, the identification of Stk40 as a regulator for fetal erythroid maturation and survival provides new clues to the molecular regulation of erythropoiesis and related diseases.…”
Publicado 2017
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7559por Meng, Qingli, Wang, Kejun, Liu, Xiaolei, Zhou, Haishen, Xu, Li, Wang, Zhaojun, Fang, Meiying“…CONCLUSION: Our results provide new clues for understanding the genetic mechanisms underlying growth traits, and may help improve these traits in future breeding programs.…”
Publicado 2017
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7560por Su, Shih-Chi, Lin, Chiao-Wen, Liu, Yu-Fan, Fan, Wen-Lang, Chen, Mu-Kuan, Yu, Chun-Ping, Yang, Wei-En, Su, Chun-Wen, Chuang, Chun-Yi, Li, Wen-Hsiung, Chung, Wen-Hung, Yang, Shun-Fa“…These findings provide clues for the design of clinical trials for targeted therapies and stratification of OSCC patients with differential therapeutic efficacy.…”
Publicado 2017
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