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  1. 7781
    “…In this study, we aimed to provide clues to the function of miR‐563 and its direct target in lung cancer. …”
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    MiR‐563 restrains cell proliferation via targeting LIN28B in human lung cancer
  2. 7782
    “…Uncovering core regulatory pathways that drive biofilm-associated growth and tolerance towards environmental stressors promises to give clues to host and environmental interactions and could provide useful targets for new clinical interventions.…”
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    Parallel evolutionary paths to produce more than one Pseudomonas aeruginosa biofilm phenotype
  3. 7783
    “…High-quality reference genomes with massive datasets of transcriptomes from various conditions can provide clues to preferred agronomic traits for breeding. …”
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    Transcriptome profiling of abiotic responses to heat, cold, salt, and osmotic stress of Capsicum annuum L.
  4. 7784
    “…Future study will be necessary to elucidate the active interactions between different viruses and bacteria and give clues to risk stratified strategy in the management of respiratory infections among young children.…”
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    Clinical significance of viral–bacterial codetection among young children with respiratory tract infections: Findings of RSV, influenza, adenoviral infections
  5. 7785
    “…This study can provide novel clues for the treatment of NPC.…”
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    LncRNA DLX6‐AS1 increases the expression of HIF‐1α and promotes the malignant phenotypes of nasopharyngeal carcinoma cells via targeting MiR‐199a‐5p
  6. 7786
    “…Thus, the simulation provides clues on experimentally inaccessible parameters and describes the functional state of the chloroplast thiol regulatory network.…”
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    Computational simulation of the reactive oxygen species and redox network in the regulation of chloroplast metabolism
  7. 7787
    “…Genomic analysis revealed abundant clues on bacterial high‐pressure adaptation and piezophilic lifestyle. …”
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    Physiological and genomic features of Paraoceanicella profunda gen. nov., sp. nov., a novel piezophile isolated from deep seawater of the Mariana Trench
  8. 7788
    “…Increased awareness through educational and screening programs will trigger lifestyle modifications that will reduce cardio-metabolic disease onset and offer clues for better disease predictive, preventive and personalized medicine.…”
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    Prevalence and lifestyle-related risk factors of obesity and unrecognized hypertension among bus drivers in Ghana
  9. 7789
    “…Exploring this collection of mechanisms is one of the clues for a future personalized medicine. The Therapeutic Performance Mapping System (TPMS) is a Systems Biology approach that generates multiple models of the mechanism of action of a drug. …”
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    In-silico simulated prototype-patients using TPMS technology to study a potential adverse effect of sacubitril and valsartan
  10. 7790
    “…Its hub and target genes, MYC, NPM1, TRPC7, UBC, FN1, HEMK1, IFT74, VHL, TAOK1, KHSRP, HSD17B11 and PAH were expected to be new targets for CAD. Our finding provided clues for exploring molecular mechanism and developing new prognostics, diagnostic and therapeutic strategies for CAD.…”
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    Analysis of Differentially Expressed Genes in Coronary Artery Disease by Integrated Microarray Analysis
  11. 7791
    “…Single-molecule real-time (SMRT) sequencing was to further identify the gene structure and gene regulation for more clues in WFS aetiology. Totally 50,049 high quality transcripts were obtained, capturing 39,995 previously mapped and 10,054 newly detected transcripts, which were annotated to 30,554 genes. …”
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    Identification of Multigene Biomarker for Shrimp White Feces Syndrome by Full-Length Transcriptome Sequencing
  12. 7792
    “…AzoA displays unique features in the active site providing clues for explaining its catalytic and thermostability features. …”
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    Mechanistic and Crystallographic Studies of Azoreductase AzoA from Bacillus wakoensis A01
  13. 7793
    “…In this study, we assembled the draft genome of wStriCN and compared it with other Wolbachia genomes to look for clues to its Jekyll and Hyde characteristics. The assembled wStriCN draft genome is 1.79 Mb in size, which is the largest Wolbachia genome in supergroup B. …”
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    Genomic Analysis of Wolbachia from Laodelphax striatellus (Delphacidae, Hemiptera) Reveals Insights into Its “Jekyll and Hyde” Mode of Infection Pattern
  14. 7794
    “…CONCLUSIONS: This bioinformatics analysis revealed that CDK1 and CDC20 might be candidate targets for diagnosis and treatment of CRC, which provided valuable clues for CRC.…”
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    CDK1 and CDC20 overexpression in patients with colorectal cancer are associated with poor prognosis: evidence from integrated bioinformatics analysis
  15. 7795
    “…PURPOSE: According to the xenohormesis theory, animals receive signals from plants that give clues about the changing environment, and thus, depending on the season of the year, animals develop physiological changes to adapt in advance to the seasonal changes. …”
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    Consumption of out-of-season orange modulates fat accumulation, morphology and gene expression in the adipose tissue of Fischer 344 rats
  16. 7796
    “…The perturbed pathways involved in COPD provide clues for further pathological mechanism studies of COPD.…”
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    Plasma Metabolomics and Lipidomics Reveal Perturbed Metabolites in Different Disease Stages of Chronic Obstructive Pulmonary Disease
  17. 7797
    “…These findings uncovered an intriguing mechanism of C19orf66 that targeting NS3 protein of ZIKV, providing clues for understanding the actions of innate immunity, and affording the possible availability of new drug targets that can be used for therapeutic intervention.…”
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    C19orf66 interrupts Zika virus replication by inducing lysosomal degradation of viral NS3
  18. 7798
    “…The use of the evolutionarily conserved DPP4 protein from different species as a functional receptor provides clues about the host range potential of hCoV-EMC. …”
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    Dipeptidyl peptidase 4 is a functional receptor for the emerging human coronavirus-EMC
  19. 7799
    “…Our findings suggested that HSD17B4, ACAA1, and PXMP4 might be new markers for NSCLC diagnosis and prognosis and might provide new clues for NSCLC treatment.…”
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    HSD17B4, ACAA1, and PXMP4 in Peroxisome Pathway Are Down-Regulated and Have Clinical Significance in Non-small Cell Lung Cancer
  20. 7800
    “…Electron microscopy is insensitive but fast, and may provide morphological clues to choice of cell line or consensus primers for nucleic acid detection. …”
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    A Systematic Approach to Novel Virus Discovery in Emerging Infectious Disease Outbreaks
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