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  1. 7821
    “…Analysis of its genome may provide clues toward the proper treatment of patients and the design of new drugs and vaccines. …”
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    Developing an ultra-efficient microsatellite discoverer to find structural differences between SARS-CoV-1 and Covid-19
  2. 7822
    “…These metabolic features of NRF2 addiction status provide clues for novel therapeutic strategies to target NRF2-addicted cancer cells.…”
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    Metabolic features of cancer cells in NRF2 addiction status
  3. 7823
    “…A transition model from the nsp7-nsp8 hexadecameric primase complex to the nsp12-nsp7-nsp8 polymerase complex is also proposed to provide clues for the understanding of the coronavirus transcription and replication machinery.…”
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    Structural Basis for RNA Replication by the SARS-CoV-2 Polymerase
  4. 7824
    “…In this study, the evolution of the PACAP system is revisited taking advantage of the burgeoning sequence data (genome and transcriptomes) available for invertebrates to uncover clues about when it first appeared. The results suggest that elements of the PACAP system are absent from protozoans, non-bilaterians, and protostomes and they only emerged after the protostome-deuterostome divergence. …”
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    Tracing the Origins of the Pituitary Adenylate-Cyclase Activating Polypeptide (PACAP)
  5. 7825
    “…Other SLIT (SLIT2 and SLIT3) mRNAs showed preferential expressions in the prefrontal cortex with a distinct laminar pattern. To obtain further clues to the role of SLIT signaling in the organization of the primate brain, we performed ISH analysis of SLIT and ROBO mRNAs using adult macaque brain tissues. …”
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    Expression patterns of SLIT/ROBO mRNAs reveal a characteristic feature in the entorhinal-hippocampal area of macaque monkeys
  6. 7826
    “…This study would provide useful clues for relevant hygienic departments making quick responses to increasingly severe epidemics in similar megacities in the world.…”
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    Early forecasting of the potential risk zones of COVID-19 in China's megacities
  7. 7827
    “…The aim of this study was to investigate the demographic, clinical, and electrophysiological characteristics of postictal generalized electroencephalography (EEG) suppression (PGES), thereby facilitating the recognition of PGES and providing clues regarding its risk factors, pathophysiology, and relationship with sudden unexpected death in epilepsy patients (SUDEP). …”
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    Periictal electroclinical characteristics of postictal generalized electroencephalographic suppression after generalized convulsive seizures
  8. 7828
    “…Further analyses using a localizer task showed that the extrastriate body area was more recruited for decoding others' self‐conscious versus BEs, which emphasize the importance of body clues to properly infer these emotions. Using an original task allowing for an ecological assessment of the affective ToM, these results demonstrate that the complexity of the emotion inferred to others can influence the recruitment of ToM network. …”
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    Influence of emotional complexity on the neural substrates of affective theory of mind
  9. 7829
    “…Through the preliminary study, a combined protocol is recommended for performing metagenomics studies, by using OM method plus KH protocol as well as suitable DNA quantity on either fresh or freeze-thaw samples. Our findings provide clues for potential variations from various DNA extraction methods, library protocols, and sample DNA inputs, which are critical for consistent and comprehensive profiling of the human gut microbiome.…”
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    Comparative Analysis of Sample Extraction and Library Construction for Shotgun Metagenomics
  10. 7830
    “…These m6A-related regulators could act as novel prognostic biomarkers for HNSCC. Our findings provide clues for understanding RNA epigenetic modifications in HNSCC.…”
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    Analysis of Genetic Alteration Signatures and Prognostic Values of m6A Regulatory Genes in Head and Neck Squamous Cell Carcinoma
  11. 7831
    “…(1) Background: Alterations in the structural composition of the human gut microbiota have been identified in various disease entities along with exciting mechanistic clues by reductionist gnotobiotic modeling. Improving health by beneficially modulating an altered microbiota is a promising treatment approach. …”
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    Prebiotic Effects of Partially Hydrolyzed Guar Gum on the Composition and Function of the Human Microbiota—Results from the PAGODA Trial
  12. 7832
    “…This discovery further supports an East African origin for the MTBC and provides additional molecular clues on the ancestral genome reduction associated with adaptation to a pathogenic lifestyle.…”
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    A sister lineage of the Mycobacterium tuberculosis complex discovered in the African Great Lakes region
  13. 7833
    “…In conclusion, comprehensive assessments can provide etiological clues in ~75% of the children with auditory neuropathy. …”
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    An integrative approach for pediatric auditory neuropathy spectrum disorders: revisiting etiologies and exploring the prognostic utility of auditory steady-state response
  14. 7834
    “…The findings, though complex, provide clues for further studies of specific mental disorders.…”
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    A unified model of shared brain structural alterations in patients with different mental disorders who experience own‐thought auditory verbal hallucinations—A pilot study
  15. 7835
    “…To determine if any structural clues might aid in the further development of the synthetic methodology, the metal-free IL [C(1)mim][DCA] (C(1)mim = 1,3-dimethylimidazolium), a room-temperature solid, crystalline analogue of the reaction IL, which is liquid at room temperature, was also prepared and structurally characterized. …”
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    Forcing Dicyanamide Coordination to f-Elements by Dissolution in Dicyanamide-Based Ionic Liquids
  16. 7836
    “…Magic-sized clusters (MSCs) can be isolated as intermediates in quantum dot (QD) synthesis, and they provide pivotal clues in understanding QD growth mechanisms. We report syntheses for two families of heterogeneous-atom-incorporated InP MSCs that have chlorine or zinc atoms. …”
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    Evolution from unimolecular to colloidal-quantum-dot-like character in chlorine or zinc incorporated InP magic size clusters
  17. 7837
    “…This study provided an atlas of genetic correlations between psychiatric disorders and plasma proteome, providing novel clues for pathogenetic and biomarkers, therapeutic studies of psychiatric disorders.…”
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    An atlas of genetic correlations between psychiatric disorders and human blood plasma proteome
  18. 7838
    “…The visual and sensorimotor areas are brain areas where perfusion is prone to change at the beginning of T1DM. Our study provided clues for cerebral pathophysiological changes in the initial stage of T1DM.…”
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    Disrupted Regional Cerebral Blood Flow in Children With Newly-Diagnosed Type 1 Diabetes Mellitus: An Arterial Spin Labeling Perfusion Magnetic Resonance Imaging Study
  19. 7839
    “…Our paper will provide mechanistic clues and therapeutic targets for physicians and investigators to combat COVID-19.…”
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    SARS-CoV-2 pathophysiology and assessment of coronaviruses in CNS diseases with a focus on therapeutic targets
  20. 7840
    “…Identification of the key role for the RAS-MAPK pathway in CBL-mediated cerebral arteriopathy could facilitate identification of novel or repurposed druggable targets for treating these patients and may also provide therapeutic clues for other cerebral arteriopathies.…”
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    Cerebral arteriopathy associated with heterozygous variants in the casitas B-lineage lymphoma gene
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