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8001por Du, Bailu, Shen, Nan, Tao, Yue, Sun, Sijuan, Zhang, Fang, Ren, Hong, Cao, Qing, Mo, Xi“…Recent advances in sequencing technology enable the characterization of the gut microbiota and can provide clues for the pathogenesis of sepsis, which may help develop biomarkers for diagnosis or prognosis prediction in children with sepsis. …”
Publicado 2021
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8002por Zhang, Zengyuan, Zhang, Yanfang, Liu, Kefang, Li, Yan, Lu, Qiong, Wang, Qingling, Zhang, Yuqin, Wang, Liang, Liao, Hanyi, Zheng, Anqi, Ma, Sufang, Fan, Zheng, Li, Huifang, Huang, Weijin, Bi, Yuhai, Zhao, Xin, Wang, Qihui, Gao, George F., Xiao, Haixia, Tong, Zhou, Qi, Jianxun, Sun, Yeping“…Our work reveals a molecular basis for cross-species transmission and potential animal spread of SARS-CoV-2, and provides new clues to block the potential transmission chains of this virus.…”
Publicado 2021
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8003por Wu, Wensi, Peng, Yongpai, Zhou, Jiaxin, Zhang, Xiaojun, Cao, Lin, Lin, Wei-jye, Lu, Yanan, Wen, Jing, Wang, Zhi“…This is the first study to explore the differential expression profiles of genes and their regulation mechanisms in PND, our results provided new clues and targets for the treatment of this refractory disease.…”
Publicado 2021
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8004“…While several studies have shown mosquitoes’ transcriptional responses to dengue virus infection, none have investigated these responses in Wolbachia, which may provide clues to the inhibition mechanism. Our results suggest changes in the expression of a number of functionally important Wolbachia genes upon dengue virus infection, including those involved in stress responses, providing insights into the endosymbiont’s reaction to virus infection.…”
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8005por Xu, Yaya, Kong, Xiangmei, Li, Jiru, Cui, Tiantian, Wei, Yifan, Xu, Jiayue, Zhu, Yueniu, Zhu, Xiaodong“…CONCLUSION: These findings suggest that activating the HIF–VEGF signaling pathway to regulate angiogenesis after infliction of hypoxic kidney injury may provide clues for the development of novel CKD treatments.…”
Publicado 2021
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8006por Li, Jingchen, Song, Guoqiang, Jin, Qianxu, Liu, Liqiang, Yang, Liang, Wang, Yuanyu, Zhang, Xuesong, Zhao, Zongmao“…Loss of Cacna2d1 can provide useful therapeutic clues for ICH treatment.…”
Publicado 2021
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8007por Marziliano, Nicola, Medoro, Alessandro, Mignogna, Donatella, Saccon, Giovanni, Folzani, Stefano, Reverberi, Claudio, Russo, Claudio, Intrieri, Mariano“…Additionally, it can provide clues in dating the presence of the SARS-CoV-2 lineage B.1.1.7 in Northern Italy in the early phases of the second pandemic wave.…”
Publicado 2021
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8008“…While epigamic traits likely evolve via sexual selection, the mechanism whereby internal sexual dimorphism arises remains less well understood. Seeking clues as to how the internal sexual dimorphism evolved, we compared the abdominal musculature of 41 Drosophila montium group species, to determine whether any of these species carry a male-specific muscle of Lawrence (MOL). …”
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8009“…Conclusions: These findings provide clues for understanding the genetic basis of MSCs originating from different organs and implicate KMT2D alteration as a frequent pathogenic mutation, allowing provision of appropriate treatment for this rare malignant disease in the future.…”
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8010“…However, TOTs are not merely instances of retrieval failures. Clues that increase the subjective likelihood of retrieval success, such as cue familiarity and target-related information, also have been shown to elicit feelings of imminent recall, supporting a metacognitive, inferential etiology of the TOT phenomenon. …”
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8011por Du, Jianke, Ge, Chunfeng, Li, Tingting, Wang, Sanhong, Gao, Zhihong, Sassa, Hidenori, Qiao, Yushan“…Furthermore, the large introns and neighboring lncRNAs in S-RNase in Fragaria could offer clues about S-RNase expression strategies.…”
Publicado 2021
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8012“…Expression analysis of Populus GATA genes identified the five PCs displaying tissue-specific expression, providing the clues of their biological functions. Amino acid patterns of Populus GATA motifs display well conserved manner of Populus GATA genes. …”
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8013por Takahashi, Shuko, Shimoda, Haruki, Sakata, Kiyomi, Ogawa, Akira, Kobayashi, Seiichiro, Kawachi, Ichiro“…Examination of the variations in health recovery may provide clues about the sources of disaster resilience.…”
Publicado 2021
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8014por Rajaei, Moein, Saxena, Ayush Shekhar, Johnson, Lindsay M., Snyder, Michael C., Crombie, Timothy A., Tanny, Robyn E., Andersen, Erik C., Joyner-Matos, Joanna, Baer, Charles F.“…Important clues about natural selection can be gleaned from discrepancies between the properties of segregating genetic variants and of mutations accumulated experimentally under minimal selection, provided the mutational process is the same in the laboratory as in nature. …”
Publicado 2021
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8015por Li, Xiuya, Gao, Fei, Wang, Xiaochen, Liang, Qianqian, Bai, Aobing, Liu, Zhuo, Chen, Xinyun, Li, Ermin, Chen, Sifeng, Lu, Chao, Qian, Ruizhe, Sun, Ning, Liang, Ping, Xu, Chen“…INTERPRETATION: Our study revealed a new role for E2A during directed cardiac differentiation of hESCs and may provide new clues for enhancing induction efficiency of SAN-like cardiomyocytes from hPSCs in the future. …”
Publicado 2021
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8016“…Our theoretical results may provide some useful clues for designing new α-glucosidase inhibitors to treat type 2 diabetes.…”
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8017por Nagae, Genta, Yamamoto, Shogo, Fujita, Masashi, Fujita, Takanori, Nonaka, Aya, Umeda, Takayoshi, Fukuda, Shiro, Tatsuno, Kenji, Maejima, Kazuhiro, Hayashi, Akimasa, Kurihara, Sho, Kojima, Masato, Hishiki, Tomoro, Watanabe, Kenichiro, Ida, Kohmei, Yano, Michihiro, Hiyama, Yoko, Tanaka, Yukichi, Inoue, Takeshi, Ueda, Hiroki, Nakagawa, Hidewaki, Aburatani, Hiroyuki, Hiyama, Eiso“…Systematic molecular profiling of HB is a promising approach for understanding the epigenetic drivers of hepatoblast carcinogenesis and deriving clues for risk stratification.…”
Publicado 2021
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8018por Peng, Haishan, Yang, Jiexia, Wang, Dongmei, Guo, Fangfang, Hou, Yaping, Yin, Aihua“…CONCLUSION: NIPT serves as a fast and early prenatal screening method, giving clues to chromosome abnormalities and providing guidance for managing pregnancy. …”
Publicado 2021
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8019por Zhang, Wencheng, Gao, Zhouyong, Guan, Mingxiu, Liu, Ning, Meng, Fanjie, Wang, Guangshun“…Overall, these data suggested that ASF1B serves as a tumor promoter and potential target for cancer therapy and provided us with clues to better understand the importance of ASF1B in many types of cancer.…”
Publicado 2021
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8020por Zhang, Jinzhong, Zhang, Xiuzhi, Wang, Lingxiao, Kang, Chunyan, Li, Ningning, Xiao, Zhefeng, Dai, Liping“…A multi-omics analysis of KPNA2 is needed to gain a deeper understanding of its multilevel molecular characteristics and provide novel clues for HCC diagnosis, prognosis, and target therapy. …”
Publicado 2021
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