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8201Combination RSL3 Treatment Sensitizes Ferroptosis- and EGFR-Inhibition-Resistant HNSCCs to Cetuximabpor Liu, Shujie, Yan, Shuai, Zhu, Jie, Lu, Ruiqing, Kang, Chujie, Tang, Kang, Zeng, Jinfeng, Ding, Mingmei, Guo, Zixiang, Lai, Xianxin, Jiang, Yinan, Wu, Siqing, Zhou, Lihua, Sun, Litao, Zhou, Zhong-Wei“…Our findings prove that FTH1 plays a vital role in ferroptosis resistance in HNSCCs and also provide clues to target HNSCCs resistant to ferroptosis induction and/or EGFR inhibition.…”
Publicado 2022
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8202por Sławińska, Martyna, Kaszuba, Agnieszka, Lange, Magdalena, Nowicki, Roman J., Sobjanek, Michał, Errichetti, Enzo“…Although this review shows that the various clinical forms of cutaneous mastocytosis may feature diagnostic dermoscopic clues, it also underlines the need for further investigation as several relevant data are missing, including evaluation of dermoscopic pattern according to anatomical locations or “lesion age”, studies on rare mastocytosis variants, evaluation of the prognostic role of dermoscopy in the context of systemic involvement, and comparative analyses with common clinical mimickers.…”
Publicado 2022
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8203por Monteleone, Giovanni, Stolfi, Carmine, Marafini, Irene, Atreya, Raja, Neurath, Markus F.“…The primary objective of this Viewpoint was to provide clues about the factors explaining discrepancies among the clinical trials. …”
Publicado 2022
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8204por Jensen, Amanda R., Lane, Alison L., Werner, Brianna A., McLees, Sallie E., Fletcher, Tessa S., Frye, Richard E.“…Thus, recent research has focused on identifying specific biological abnormalities in autism spectrum disorder that can provide clues to diagnosis and treatment. Biomarkers are an objective way to identify and measure biological abnormalities for diagnostic purposes as well as to measure changes resulting from treatment. …”
Publicado 2022
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8205por Hwang, Seon Young, Jang, Hye Ji, Kim, Young Jun, Maeng, Ju Young, Park, Go Eun, Yang, Seo Young, Rhee, Choong Kyun, Sohn, Youngku“…The present new findings provide useful clues for the development of hybrid electro-and photo-catalysts tested under various experimental conditions in energy and environment.…”
Publicado 2022
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8206por Qin, Jiaxin, Cao, Zhanglei, Cai, Xia, Fang, Yu, An, Baoju, Li, Xuelian, Zhang, Yizhuo, Tian, Hongwei, Hu, Wenzhuo, Yan, Bing, Cai, Jun“…Overall, this study provides essential clues for future studies exploring the function of the NupR homolog in other bacteria, such as Bacillus cereus, Bacillus anthracis, Klebsiella pneumoniae, and Streptococcus pneumoniae. …”
Publicado 2022
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8207por Zhuo, Chuanjun, Tian, Hongjun, Chen, Jiayue, Li, Qianchen, Yang, Lei, Zhang, Qiuyu, Chen, Guangdong, Cheng, Langlang, Zhou, Chunhua, Song, Xueqin“…Moreover, the present data demonstrate three-way SNP-FC-GMV associations in patients with SCZ, thus providing clues regarding potential genetic bases of cognition impairments in SCZ. …”
Publicado 2022
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8208por Jacobsen, Gillian E., Fernández, Irina, Quintero, Maria A., Santander, Ana M., Pignac-Kobinger, Judith, Damas, Oriana M., Deshpande, Amar R., Kerman, David H., Ban, Yuguang, Gao, Zhen, Silva, Tiago C., Wang, Lily, Beecham, Ashley H., McCauley, Jacob L., Burgueño, Juan F., Abreu, Maria T.“…CONCLUSIONS: Lamina propria phagocytes from IBD mucosa provide pathogenetic clues on the nature of treatment refractoriness and inform new targets for therapy.…”
Publicado 2022
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8209“…CONCLUSION: Our study holds potential to identify novel candidate causal pathways and provides clues for revealing the complex genetic mechanism of PSC.…”
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8210por Tao, Wendan, Kwapong, William Robert, Xie, Jianyang, Wang, Zetao, Guo, Xiaonan, Liu, Junfeng, Ye, Chen, Wu, Bo, Zhao, Yitian, Liu, Ming“…CONCLUSION: Our report suggests that imaging of the retinal microvasculature may give clues to brain frailty in the aging population.…”
Publicado 2022
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8211“…CONCLUSION: The standard strain L. paralimentarius (DSM 13238) is a promising ensiling inoculant for corn stover silage. The findings provide clues on strategies to select LAB to improve the quality of silage.…”
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8212por Huo, Yingduo, Gu, Yang, Cao, Mulian, Mao, Yingrui, Wang, Yayu, Wang, Xiaoqiang, Wang, Guiling, Li, Jiale“…Based on the above experimental results, it can be speculated that Hc-Tex11 and Hc-Meig1 are important in the development of the male gonadal and spermatogenesis in H. cumingii, which can provide important clues to better comprehend the molecular mechanism of Tex11 and Meig1 in regulating spermatogenesis of bivalves.…”
Publicado 2022
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8213por Chen, Xiaoyan, Zheng, Zhong, Xiao, Lili, Liu, Chengqi, Shen, Ying, Ma, Ning, Dong, Hongjun, Yin, Shankai, Feng, Yanmei“…OBJECTIVES: This study aims to explore the relationship between bone-turnover biomarkers and the recovery of SSNHL to provide clues for further improvements in etiological research and predictors. …”
Publicado 2022
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8214por Hirtz, Alex, Lebourdais, Nolwenn, Thomassin, Magalie, Rech, Fabien, Dumond, Hélène, Dubois-Pot-Schneider, Hélène“…Together, these results establish, for the first time, the involvement of hormones in low-grade and anaplastic gliomas and provide clues for refining their classification and, thus, facilitating more personalized management of patients. …”
Publicado 2022
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8215por Zhou, Jia, Yue, Shuangming, Du, Jingjing, Xue, Benchu, Wang, Lizhi, Peng, Quanhui, Zou, Huawei, Hu, Rui, Jiang, Yahui, Wang, Zhisheng, Xue, Bai“…The results present important clues for understanding the mechanisms by which NCG supplementation promotes follicular development in yaks. …”
Publicado 2022
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8216“…As a conclusion, accurate recognition of the imaging features of MNTI combined with history and clinical manifestations (early infancy, painless, firm, pigmented mucosa, non-ulcerating lesion) can provide clues for diagnosis of this rare entity.…”
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8217por Gan, Pei-Ling, Huang, Shu, Pan, Xiao, Xia, Hui-Fang, Zeng, Xin-Yi, Ren, Wen-Sen, Zhou, Xian, Lv, Mu-Han, Tang, Xiao-Wei“…Burst keywords (e.g., sofosbuvir, burden, care, sarcopenia, chronic liver failure, human gut microbiome, and nonalcoholic fatty liver disease) and a succession of reference citation bursts have provided clues about research frontiers in recent years. CONCLUSION: This study identified developing trends in the evolution of liver cirrhosis to provide new inspiration for researchers.…”
Publicado 2022
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8218por Li, Zhen, Li, Chunlin, Liang, Yuting, Wang, Keyang, Wang, Li, Zhang, Xu, Wu, Qingqing“…This study may provide clues for the early detection of fetuses with ICL/P, and be vital for preconception and prenatal counseling with non-invasive methods.…”
Publicado 2022
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8219“…These findings provide novel clues for further understanding the functional differentiation and maturation of hepatocytes during liver development.…”
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8220“…Herein, ARX/PDX1 association with DAXX/ATRX/MEN1 and ALT can be studied through pathological assessment, as these biomarkers may provide important clues to the mechanism underlying disease pathogenesis. …”
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