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8221por Hong, Yaqiang, Zhang, Dake, Zhou, Xiangtian, Chen, Aili, Abliz, Amir, Bai, Jian, Wang, Liang, Hu, Qingtao, Gong, Kenan, Guan, Xiaonan, Liu, Mengfei, Zheng, Xinchang, Lai, Shujuan, Qu, Hongzhu, Zhao, Fuxin, Hao, Shuang, Wu, Zhen, Cai, Hong, Hu, Shaoyan, Ma, Yue, Zhang, Junting, Ke, Yang, Wang, Qian-Fei, Chen, Wei, Zeng, Changqing“…Postzygotic mutations are acquired in normal tissues throughout an individual’s lifetime and hold clues for identifying mutagenic factors. Here, we investigated postzygotic mutation spectra of healthy individuals using optimized ultra-deep exome sequencing of the time-series samples from the same volunteer as well as the samples from different individuals. …”
Publicado 2022
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8222por Kirkinen, Tuija, López-Costas, Olalla, Martínez Cortizas, Antonio, Sihvo, Sanna P., Ruhanen, Hanna, Käkelä, Reijo, Nyman, Jan-Erik, Mikkola, Esa, Rantanen, Janne, Hertell, Esa, Ahola, Marja, Roiha, Johanna, Mannermaa, Kristiina“…This study reveals the first animal hairs and feathers from a Finnish Mesolithic funerary context, and provides clues about how their preservation was possible.…”
Publicado 2022
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8223por He, Xin, Ma, RuLin, Li, Yu, Wang, Haixia, Yan, YiZhong, Mao, YiDan, Liao, ShengYu, Sun, XueYing, Guo, ShuXia, Guo, Heng“…And these three miRNAs may serve as biomarkers to provide clues to the potential pathogenesis of H-type hypertension.…”
Publicado 2022
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8224“…Our study provides significant clues for the elucidation of eRNAs in STAD and may help improve the overall survival for STAD patients.…”
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8225por Li, Han, Zhao, Meng, Fei, Gaoqiang, Wang, Zemin, Wang, Shuai, Wei, Pingmin, Li, Wei“…The above results provided precise clues for the prevention and treatment of lung cancer in China.…”
Publicado 2022
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8226por Wang, Gang, Zheng, Huiyuan, Chen, Xiaoqian, Zheng, Jing, Zhan, Jiabin, Li, Rui, Qi, Yanyan, Ye, Yi, Zeng, Min, Wei, Xin“…These results might contribute to the understanding of the underlying mechanisms of recurrence and provide novel clues for precision therapy in CRSwNP.…”
Publicado 2022
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8227por Caetano, Mônica Maria Magalhães, Moreira, Gabriela Alves, da Silva, Maria Roméria, Guimarães, Gabriela Rapozo, Santos, Leandro de Oliveira, Pacheco, Amanda de Ambrósio, Siqueira, Raoni Pais, Mendes, Flávia Carneiro, Marques Da Silva, Eduardo De Almeida, Junior, Abelardo Silva, Rangel Fietto, Juliana Lopes, Saito, Ângela, Boroni, Mariana, Bressan, Gustavo Costa“…As the used compounds could target at least both SRPK1 and SRPK2, here we sought to obtain additional clues regarding the involvement of these paralogs in melanoma progression. …”
Publicado 2022
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8228por Zhong, Tingting, Qi, Yunwen, Li, Rui, Zhou, Huadong, Ran, Boli, Wang, Jiao, Cai, ZhiYou“…CONCLUSIONS: Patients with more severe ICAS are more likely to have WMHs progression and have distinct relevancy to PVWMHs and SCWMHs, which may provide clues for understanding mechanisms of WMHs progression.…”
Publicado 2022
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8229por Cappuccio, Gerarda, De Bernardi, Margherita Lucia, Morlando, Alessia, Peduto, Cristina, Scala, Iris, Pinelli, Michele, Bellacchio, Emanuele, Gallo, Flavio Gioele, Magli, Adriano, Plaitano, Carmen, Serrano, Mercedes, Pías, Leticia, Català, Jaume, Bolasell, Mercè, Torella, Annalaura, Nigro, Vincenzo, Zanni, Ginevra, Brunetti‐Pierri, Nicola“…The presented individuals suggest that retinopathy and postnatal microcephaly are clinical clues of RPL10‐related disorder, and at least the retinal defect might be more specific for the p.…”
Publicado 2022
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8230por Wu, Jinghua, Yu, Yi, Yao, Xinmeng, Zhang, Qinzhun, Zhou, Qin, Tang, Weihong, Huang, Xianglong, Ye, Chengyin“…CONCLUSIONS: This study presented a comprehensive and systematic overview of the research status of childhood asthma, provided clues to future research directions, and highlighted two significant research trends of asthma management and atopy in this field.…”
Publicado 2022
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8231por Aslam, Aaqib, Rather, Shagufta, Hussain, Arshad, Younus, Faizan, Saqib, Najam U, Hassan, Iffat“…Pruritus with temporal relation to substance use, stigmata of injectable drug use including track marks and sooting tattoos, atrophic scars at injection sites, active skin ulcers, and skin and soft tissue infections, and hyperhidrosis are among important dermatological clues for detecting substance use. Recognition of such cutaneous signs is important in these cases for more effective diagnosis and treatment.…”
Publicado 2022
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8232“…Our results undoubtedly provide scholars with new clues and ideas in this field.…”
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8233“…Our experiments showed that the miR-193a-5p/ZFP57/Wnt pathway mediated the radioresistance of pancreatic cancer cells, providing novel clues for the treatment of pancreatic cancer.…”
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8234por Liu, Tianyu, Yang, Lei, Lv, Xiaolong, Zuo, Chunjian, Jia, Chenhao, Yang, Zelin, Fan, Chongqi, Chen, Huanwen“…CONCLUSIONS: This study offers updated and comprehensive clues that variants in the IL-17 family genes are significantly linked with susceptibility to cervical, lung cancer, asthma, multiple sclerosis, rheumatoid arthritis and spondyloarthritis, and elucidates the crucial role of the IL-17 regions in the genetic predisposition to cancer or noncancerous diseases.…”
Publicado 2022
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8235por El-Shall, Nahed A., El-Hamid, Hatem S. Abd, Elkady, Magdy F., Ellakany, Hany F., Elbestawy, Ahmed R., Gado, Ahmed R., Geneedy, Amr M., Hasan, Mohamed E., Jaremko, Mariusz, Selim, Samy, El-Tarabily, Khaled A., El-Hack, Mohamed E. Abd“…Under a microscope, the presence of particular lesions and inclusion bodies may provide clues. Traditional virus isolation in avian tissue culture is more delicate than in avian embryonated eggs. …”
Publicado 2022
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8236“…To sum up, our analysis describes possible mechanisms linking COVID-19 and PD, elucidating some unknown clues in between.…”
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8237“…This case may provide clues for additional study of the immune reactivation effect of SBRT or the underlying mechanism of RCCEP.…”
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8238por Bhattacharyya, Paromik, Sharma, Tanvi, Yadav, Abhinandan, Lalthafamkimi, Lucy, Ritu, Swarnkar, Mohit Kumar, Joshi, Robin, Shankar, Ravi, Kumar, Sanjay“…Expression analysis of genes associated with β-sitosterol and eugenol biosynthesis in leaf and pseudobulb provided vital clues for differential accumulation of metabolites in M. acuminata. …”
Publicado 2022
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8239por Dai, Liping, Lu, Xueli, Shen, Lan, Guo, Longbiao, Zhang, Guangheng, Gao, Zhenyu, Zhu, Li, Hu, Jiang, Dong, Guojun, Ren, Deyong, Zhang, Qiang, Zeng, Dali, Qian, Qian, Li, Qing“…Thus, these results provide clues for elucidating the genetic basis of SV control. …”
Publicado 2022
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8240“…This review aims to provide a basis for the mechanistic study of AAT and new clues to address the challenges in AAT tolerance, tumor angiogenesis and metastasis.…”
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