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  1. 8261
    “…Overall, our study uncovers the vital roles of MIR31 in balancing inflammation and the recovery of epithelia in colitis, providing potential clues for the development of therapeutic targets in drug design.…”
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    The spring-like effect of microRNA-31 in balancing inflammatory and regenerative responses in colitis
  2. 8262
    “…Collectively, we found that the PDNT algorithm provides a measure from another view compared with the log2FC and p-value and it may provide more clues to effectively evaluate ncRNA.…”
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    A pathway analysis-based algorithm for calculating the participation degree of ncRNA in transcriptome
  3. 8263
    “…The aims of this report are to share the clinical course and discuss clues to the early diagnosis of CDI in T2D. CASE REPORT: A 70-year-old Japanese woman developed T2D with hyperglycemia symptoms, including thirst, polydipsia, and polyuria. …”
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    A 75-Year-Old Woman with a 5-Year History of Controlled Type 2 Diabetes Mellitus Presenting with Polydipsia and Polyuria and a Diagnosis of Central Diabetes Insipidus
  4. 8264
    “…This is, to the best of our knowledge, the first report of the impact of PI(4,5)P(2) acyl-chain composition on cation-dependent nanodomain ordering, and provides important clues to the motives behind the enrichment of PI(4,5)P(2) with polyunsaturated acyl-chains. …”
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    Acyl-chain saturation regulates the order of phosphatidylinositol 4,5-bisphosphate nanodomains
  5. 8265
    “…These candidate genes offer important clues for a better understanding of developmental regulations of berry enlargement in grapevine. …”
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    Integrative genomic and transcriptomic analyses of a bud sport mutant ‘Jinzao Wuhe’ with the phenotype of large berries in grapevines
  6. 8266
    “…Our results also provide clues for future research on their physiological and molecular adaptation mechanisms to light and temperature.…”
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    A comparison of 25 complete chloroplast genomes between sister mangrove species Kandelia obovata and Kandelia candel geographically separated by the South China Sea
  7. 8267
    “…Findings from this study may provide clues for further research and improve management of patients with GNDs and/or parkinsonism.…”
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    Parkinsonism in Genetic Neurodevelopmental Disorders: A Systematic Review
  8. 8268
    “…CONCLUSIONS: These results provide new insights and important clues for exploring the molecular mechanisms underlying GIGR.…”
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    Transcription analyses of differentially expressed mRNAs, lncRNAs, circRNAs, and miRNAs in the growth plate of rats with glucocorticoid-induced growth retardation
  9. 8269
    “…This study provides a reference for the identification of the 14-3-3 gene family in other plants, and provides important clues for cloning potential candidates in response to abiotic stresses in potato.…”
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    Genome-Wide Identification of 14-3-3 gene family reveals their diverse responses to abiotic stress by interacting with StABI5 in Potato (Solanum tuberosum L.)
  10. 8270
    “…Our case may provide some clues to better understand this spectrum of disease as well as the rationale for selecting medications. …”
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    A case of NASH with genetic predisposition successfully treated with an SGLT2 inhibitor: a possible involvement of mitochondrial dysfunction
  11. 8271
    “…Taken together, our work expands the base editing toolkits, and also provides important clues for the potential evolutionary process of deaminases.…”
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    TadA orthologs enable both cytosine and adenine editing of base editors
  12. 8272
    “…Here, we report the first in vivo exploration of changing the local protein environment on the energy level of the red Chls, providing new clues for engineering red/blue-shifted crops.…”
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    LHCA4 residues surrounding red chlorophylls allow for fine-tuning of the spectral region for photosynthesis in Arabidopsis thaliana
  13. 8273
    “…Together, the present study largely improved the annotation of rat genome and revealed gene expression changes at isoform level, extending the understanding of the complexity of gene regulation in Ang II-treated RAECs, and also provided novel clues for discovering the regulatory mechanism undelying Ang II caused vascular senescence and diseases.…”
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    Integrative analysis of Iso-Seq and RNA-seq reveals dynamic changes of alternative promoter, alternative splicing and alternative polyadenylation during Angiotensin II-induced senescence in rat primary aortic endothelial cells
  14. 8274
    “…In this way, multiple-perspective clues are taken into account to reflect the most essential pathological manifestation on CT images. …”
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    Self-paced Multi-view Learning for CT-based severity assessment of COVID-19
  15. 8275
    por Gwak, Ho-Shin
    Publicado 2023
    “…This review examines extant research on the metastatic cascade of BM through the molecular events that create and sustain BM to reveal clues that can assist the development of effective targeted therapies that treat established BMs and prevent BM recurrence.…”
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    Molecular Biology of Brain Metastases
  16. 8276
    “…Deciphering the exact mechanism of how MSA can result from genetic aberrations in both experimental and clinical models will facilitate the identification of novel pathophysiologic clues, and pave the way for translational research into the development of disease-modifying therapeutic targets.…”
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    The genetic basis of multiple system atrophy
  17. 8277
    “…The subgingival microbiome can offer important clues in the investigation of the pathogenesis and treatment of halitosis.…”
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    Non-Surgical Periodontal Treatment Impact on Subgingival Microbiome and Intra-Oral Halitosis
  18. 8278
    “…However, there are still remaining clues to be solved in the pathogenesis and diagnosis of the disease. …”
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    Immunopathological mechanisms in the early stage of Mycobacterium avium subsp. paratuberculosis infection via different administration routes in a murine model
  19. 8279
    “…Introduction: Anthropometric measurements of the distal femoral fragment play a crucial role in prosthesis design during arthroplastic knee surgeries and offer valuable clues for stature estimation in forensic investigations. …”
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    Anthropometric Analysis of Distal Femur Parameters in the Eastern Uttar-Pradesh Population
  20. 8280
    “…Overall, this study provides molecular clues and a multifaceted understanding of the specific response of cherry to A. alternata.…”
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    Comparative transcriptome and metabolome analyses of cherry leaves spot disease caused by Alternaria alternata
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