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  1. 8341
    por Liu, Zhenya, Chen, Cancan, Hu, Yanli
    Publicado 2023
    “…The results of this study may provide clues to help identify factors influencing caregivers’ quality of life and implement targeted strategies to improve their quality of life.…”
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    Factors related to the quality of life of family cancer caregivers
  2. 8342
    “…Research has identified diagnostic clues, neurotransmitter pathways, and psychiatric comorbidities related to ADHD, as well as effective pharmacologic, behavioral, and psychosocial interventions. …”
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    Changes and Challenges: Managing ADHD in a Fast-Paced World
  3. 8343
    “…Improved understanding of the response to viral infections of the human CNS may provide clues for how to manipulate these processes to improve outcomes.…”
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    Pathogenesis and outcome of VA1 astrovirus infection in the human brain are defined by disruption of neural functions and imbalanced host immune responses
  4. 8344
    “…As per our knowledge, this study is of its kind where pathogenic fungal sclerotia activated microbes with a potential role in N transformation and provided clues about the ecological functions of R. solani sclerotia on the stimulation of bacterial genera involved in different processes of N-cycle within the soil in the absence of host plants. …”
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    Enrichment of bacteria involved in the nitrogen cycle and plant growth promotion in soil by sclerotia of rice sheath blight fungus
  5. 8345
    “…As far as we know, this is the first case reporting the clinical, immunological, and molecular changes in mast cell leukemia patients before and after midostaurin treatment, illustrating the in vivo mechanisms of midostaurin resistance in mast cell leukemia, providing important clues to develop a sequential option to circumvent tumor progression after targeting oncogene addiction and prolong patients’ survival.…”
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    Case Report: Molecular and microenvironment change upon midostaurin treatment in mast cell leukemia at single-cell level
  6. 8346
    “…The bacterial genomes provide clues of a long evolutionary history with these enigmatic worms. …”
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    A dynamic epibiont community associated with the bone-eating polychaete genus Osedax
  7. 8347
    “…At the same time, they provided important clues and key immune factors for dealing with complicated pulmonary infections.…”
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    K. pneumoniae and M. smegmatis infect epithelial cells via different strategies
  8. 8348
    “…Hence a direct comparison of latency characteristics between HIV-1 and HIV-2 could provide important clues towards a functional cure. Transduction of SupT1 cells with single-round HIV-1 and HIV-2 viruses with an enhanced green fluorescent protein (eGFP) reporter showed higher levels of eGFP expression for HIV-2 than HIV-1, while HIV-1 expression appeared more cytotoxic. …”
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    The HIV-2 OGH double reporter virus shows that HIV-2 is less cytotoxic and less sensitive to reactivation from latency than HIV-1 in cell culture
  9. 8349
    “…The genotypes with high FTSW-NTR thresholds, high SCMR, and low CTD may be useful clues in identifying a genotype’s ability to adapt to moisture stress. …”
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    Safflower (Carthamus tinctorius L.) crop adaptation to residual moisture stress: conserved water use and canopy temperature modulation are better adaptive mechanisms
  10. 8350
    “…These results provide novel clues as to how DMN may contribute to executive task performance. …”
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    Planning ahead: Predictable switching recruits task‐active and resting‐state networks
  11. 8351
    “…Our study revealed the causal effect of gut microbiota on sleep and identified causal risk and protective taxa for chronotype, sleep duration, snoring and insomnia, which has the potential to provide new perspectives for future mechanistic and clinical investigations of microbiota-mediated sleep abnormal patterns and provide clues for developing potential microbiota-based intervention strategies for sleep-related conditions.…”
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    Causal Effects of Gut Microbiota on Sleep-Related Phenotypes: A Two-Sample Mendelian Randomization Study
  12. 8352
    “…Our study sheds light on the remarkable adaptability of wood-feeding insects and provides valuable clues to their evolutionary success on this challenging, nutrient-poor resource. …”
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    Reevaluating Symbiotic Digestion in Cockroaches: Unveiling the Hindgut’s Contribution to Digestion in Wood-Feeding Panesthiinae (Blaberidae)
  13. 8353
    “…Thus, elucidation of the mechanisms through which SAP occurs in obese individuals will provide clues for possible treatment targets. Differences in early events in obese or lean patients with AP have not been conclusively reported. …”
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    Activation of AMPK ameliorates acute severe pancreatitis by suppressing pancreatic acinar cell necroptosis in obese mice models
  14. 8354
    “…The model can learn imaging features containing both pathological morphology and underlying biological clues to achieve the integrated diagnosis. Our model achieves high performance with area under receiver operator curve all above 0.90 in classifying major tumor types, in identifying tumor grades within type, and especially in distinguishing tumor genotypes with shared histological features. …”
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    Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images
  15. 8355
    “…The current study provided new clues for early diagnosis and treatment for SIONFH.…”
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    Plasma 8-OHdG act as a biomarker for steroid-induced osteonecrosis of the femoral head
  16. 8356
    por Gu, Xuelan, Cui, Xiao, Zhang, Hong, Mi, Grace
    Publicado 2023
    “…These findings provide new clues to explain how pollution affects skin innate defense, host–microbe interactions and contributes to abnormal skin conditions. …”
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    SG-APSIC1094: Impact of environmental pollution on skin antimicrobial peptide genes expression revealed by transcriptome profiling
  17. 8357
    “…Taken together, this study may help to reveal the complex regulatory process of wheat adaptation to Pi starvation and provide new genetic clues for further study on improving plant Pi utilization efficiency.…”
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    Integrated Analysis of Metabolome and Transcriptome Reveals Insights for Low Phosphorus Tolerance in Wheat Seedling
  18. 8358
    “…The purpose of this study was to provide educational ideas for insufficient exercise and provide clues for the design of effective and safe exercise intervention programs with high compliance in patients of advanced liver cancer in the future. …”
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    The relationship of exercise and cancer-related fatigue in patients with advanced liver cancer: a cross-sectional study
  19. 8359
    “…We also uncovered the importance of HutZ for the success of Av. paragallinarum infection and provided new clues to the pathogenesis strategies of this organism. …”
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    HutZ is required for efficient heme utilization and contributes to the pathogenicity of Avibacterium paragallinarum
  20. 8360
    “…This study not only displayed a new framework to expand the abundant CRISPR-Cas and anti-CRISPR systems for functional gene characterizations but also provided new insights into the regulation of multidrug resistance in P. aeruginosa and important clues for precise anti-pseudomonal therapies.…”
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    A type I-F CRISPRi system unveils the novel role of CzcR in modulating multidrug resistance of Pseudomonas aeruginosa
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